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Attovial-based antibody nanoarrays.

Antibody array-based technology is a powerful emerging tool in proteomics, but to enable global proteome analysis, antibody array layouts with even higher density has to be developed. To this end, we have further developed the first generation of a nanoarray platform, based on attoliter sized vials, attovials, which we have characterized and used for the detection of complement factor C1q in human

Down-modulation of the antigen receptor by a superantigen for human B cells

B cell superantigens (SAgs) have been implicated in human diseases by demonstrating non-clonotypic expansion of B cells bearing certain immunoglobulin variable region genes. One possibility is that, during infection with microorganisms secreting SAgs, these potent molecules might modulate BcR expression. To test this hypothesis, we investigated the potential effects of a SAg, protein L from Peptos

Human intestinal lamina propria and intraepithelial lymphocytes express receptors specific for chemokines induced by inflammation

To determine which chemokine receptors might be involved in T lymphocyte localization to the intestinal mucosa, we examined receptor expression on human intestinal lamina propria lymphocytes (LPL), intraepithelial lymphocytes (IEL) and CD45RO+beta7hi gut homing peripheral blood lymphocytes (PBL). Virtually all LPL and IEL expressed CXCR3 and CCR5, receptors that have been associated with Th1(Tc1)/

Dynamic studies on the sintering of compacted metal powders using an environmental scanning electron microscope

The sintering of pre-pressed powders of iron, copper and nickel has been studied in situ using an Environmental scanning electron microscope. The small samples were slowly heated to sintering temperatures in a reducing atmosphere. Continuous monitoring of the fracture surface of the sample revealed the initial formation of inter-particle bonds at relatively low temperatures for fine particles. The

An integrative transcriptome analysis reveals a functional role for thyroid transcription factor-1 in small cell lung cancer

Small cell lung cancer (SCLC) is a neuroendocrine tumour that exhibits rapid growth and metastatic spread. Although SCLC represents a prototypically undifferentiated cancer type, thyroid transcription factor-1 (TTF-1, gene symbol NKX2-1), a master regulator for pulmonary epithelial cell differentiation and lung morphogenesis, is strongly upregulated in this aggressive cancer type. The aim of this

In vitro starch digestibility of fresh and sun-dried faba beans (Vicia faba L.)

Fresh and sun-dried faba beans (Vicia faba L.) were cooked, stored for various times at 4°C and analysed for available starch (AS), resistant starch (RS) and fibre-associated resistant starch (FARS) contents as well as α-amylolysis. Fresh beans required a shorter cooking time (25 min) than dried beans (158 min). Cooked fresh faba beans had a higher AS content than cooked dried faba beans. The AS c

Joseph Beuys : fett och filt : en forskningskritisk essä

Joseph Beuys. Fat and felt. A critical essay. The extremely singular materials fat and felt for use in art, have an entirely dominating role in a long series of Joseph Beuys’ (1921-1986) most important work. They are found both in single works of art as well as in installations and happenings from the beginning of the 1960s and up to the end of the artist’s life. This essay deals with the artist’

Quantitative analysis of rat Ig (sub) classes binding to cell surface antigens

An indirect 125I-labeled protein A assay for detection of cell surface-bound rat immunoglobulins is presented. The assay is quantitative and rapid and detects as little as 1 ng of cell surface-bound Ig. It discriminates between antibodies belonging to different IgG subclasses, IgM and IgA. We describe the production and specificity control of the reagents used and show that the test can be used fo

Pathogenetic Mechanisms in Soft Tissue Tumors

Soft tissue tumors (STT) constitute a heterogeneous group of tumors that arise in tissues of mesenchymal origin. They are currently classified according to morphology and resemblance to normal tissue into over 100 subtypes. Differentiation between the different subtypes can sometimes be difficult, and along with the fact that little is known about the mechanisms of STT development, this makes adeq

Riktlinjer fu reviderade 151014

Riktlinjer FU reviderade_151014   Ins t i tu t ionen   fö r     serv ice  management  och   t jäns teve tenskap               RIKTLINJER FÖR FORSKARUTBILDNING I TJÄNSTEVETENSKAP Revidering fastställd av styrelsen för service management och tjänstevetenskap den 14 oktober 2015. Dnr STYR 2015/1162 De första doktoranderna i tjänstevetenskap antogs våren 2006. Vår ambition vid institutionen för servic

https://www.ses.lu.se/sites/ses.lu.se/files/riktlinjer_fu_reviderade_151014.pdf - 2026-06-03

Styr 2017 960 riktlinjer fu

Microsoft Word - Rev_beslut_riktlinjer_170607.doc   Ins t i tu t ionen   fö r     serv ice  management  och   t jäns teve tenskap               RIKTLINJER FÖR FORSKARUTBILDNING I TJÄNSTEVETENSKAP Revidering fastställd av styrelsen för service management och tjänstevetenskap den 7 juni 2017. Dnr STYR 2017/960 De första doktoranderna i tjänstevetenskap antogs våren 2006. Vår ambition vid institution

https://www.ses.lu.se/sites/ses.lu.se/files/styr_2017_960_riktlinjer_fu.pdf - 2026-06-03

Generalsafetyroutines

General safety routines and info DEPARTMENT OF BIOLOGY | LUND UNIVERSITY 2 GENERAL SAFETY ROUTINES AND INFO Table of contents In the lab .......................................................................................................... 3 Sign checklist ............................................................................................. 3 Risk assement .............................

https://www.biologi.lu.se/internt/sites/biologi.lu.se.internt/files/2022-07/generalsafetyroutines.pdf - 2026-06-03

Multi-scale wave modelling; Field validation in Faxe Bay, Denmark

Access to local nearshore wave climate conditions on a detailed spatial scale is important for many coastal engineering practices. These include assessing the flood risk of coastal infrastructure, designing coastal protection measures, and estimating sediment transport processes and wave run-up. The present study displays a multi-scale wave modelling approach using the numerical wave model SWAN (B