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Importance of individual residues in hydrophobic patch PLVIVGL (1481-1487) in FV-Short for synergistic TFPIα cofactor activity with protein S, an alanine-scanning study: AlphaFold-mediated prediction of FV-Short/TFPIα/protein S trimolecular complex structure

BackgroundIn the splice variant factor (F)V-Short, 702 residues are deleted from the B domain, resulting in exposure of an acid region (AR2; 1493-1537) that binds TFPIα. FV-Short and protein S serve as synergistic TFPIα cofactors in inhibition of FXa. In the preAR2 region, a hydrophobic patch PLVIVGL (1481-1487) is crucial for synergistic TFPIα-cofactor activity and assembly of FV-Short, TFPIα, an

A method to stretch the retina in vitro and monitor effects on Müller glial cells

The retina is a thin tissue layer on the inside of the eye and may be subject to tractional forces in diseases like myopia, retinoschisis, and retinal detachment. Müller glial cells (MGCs) are the only cells spanning the entire retinal thickness and hypothetically respond to mechanical stress imposed across retinal layers. We designed a device to apply force in vitro perpendicular to the retinal s

Disputationer 2023

Max HjärtströmCompetition Law's Market Failure Paradox: Economic Efficiency, Consumer Welfare and Public Policy in EU Antitrust and State Aid LawDatum för disputationen: 18 december   Fakultetsopponent: Professor Chris Townley, King`s collegeÄmne: civilrättAbstractContemporary markets grapple with pressing challenges to secure socially and economically outcomes. Against this backdrop, market failu

https://www.jur.lu.se/forskning/disputationer/disputationer-2023 - 2026-06-11

Så kan man använda militära strategier mot cancer – Vetenskap och Hälsa

Så kan man använda militära strategier mot cancer – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Så kan man använda militära strategier mot cancer 2017-02-02 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Kan militära strategier använda

https://www.vetenskaphalsa.se/sa-kan-man-anvanda-militara-strategier-mot-cancer/ - 2026-06-12