Sökresultat

This thesis is based upon four original papers describing the characterisation of mantle cell lymphoma (MCL) tumours and cell lines in comparison with different populations of normal B cells. Gene expression profiling, which were used in the studies, has during recent years developed as an important tool in characterisation of different types of malignancies. In this thesis, the technique is used

Animals with color vision use color information in intra- and interspecific communication, which in turn may drive the evolution of conspicuous colored body traits via natural and sexual selection. A recent study found that the transparent wings of small flies and wasps in lower-reflectance light environments display vivid and stable structural color patterns, called "wing interference patterns" (

We consider a popular model for long-duration gamma-ray bursts, in which the progenitor star, a stripped helium core, is spun up by tidal interactions with a black hole companion in a compact binary. We perform population synthesis calculations to produce a representative sample of such binaries, and model the effect that the companion has on material that falls back on to the newly formed black h

Antibody-based microarrays are a rapidly evolving affinity-proteomic methodology that recently has shown great promise in clinical applications. The resolution of these proteomic analyses is, however, directly related to the number of data-points, i.e. antibodies, included on the array. Currently, this is a key bottleneck due to limited availability of numerous highly-characterized antibodies. Her

The article analyzes the recent genre of Islamic children’s picture books, originally produced as a means of religious socialization for the British Muslim communities, but marked on a global Islamic market. Particular attention is devoted to the visual norms of the books produced by one of the pioneering publishers of Islamic children’s literature, the Islamic Foundation. With one foot in the ped

The epidemiology, the fracture pattern and the clinical relevance of prevalent vertebral fractures in old men are debated wherefore we set out to clarify these issues.

We test asteroseismic radii of Kepler main-sequence and subgiant stars by deriving their parallaxes which are compared with those of the first Gaia data release. We compute radii based on the asteroseismic scaling relations as well as by fitting observed oscillation frequencies to stellar models for a subset of the sample, and test the impact of using effective temperatures from either spectroscop

In this first investigation of the MOCCA database with respect to cataclysmic variables, we found that for models with Kroupa initial distributions, considering the standard value of the efficiency of the common-envelope phase adopted in BSE, no single cataclysmic variable was formed only via binary stellar evolution, i. e., in order to form them, strong dynamical interactions have to take place.

The choice of expressions for the coding probabilities in general, and the escape probability in particular, is of great importance in the family of PPM algorithms. We present a parameterized version of the escape probability estimator which, together with a 'compactness' criterion, provides guidelines for the estimator design given a 'representative' set of files. This parameterization also makes

Background and purpose — Rates of knee replacement (KR) are increasing worldwide. Based on population and practice changes, there are forecasts of a further exponential increase in primary knee replacement through to 2030, and a corresponding increase in revision knee replacement. We used registry data to document changes in KR over the past 15 years, comparing practice changes across Sweden, Aust

Not long ago the rise of monasticism was taken to be the creation of a Sonderwelt – an idea which also seemed to be reflected in the ancient literary material: the desert became a city of its own. However, a contradiction between city and monastery is often bridged by the very literature that created the rift, because texts travelled both ways – just as people did. In the context of this short con

High-quality biosecurity practices are critical to restarting international tourism. Effective market segmentation improves the communication and efficacy of health advice. Travel frequency is an important basis for health-related consumer segmentation, as it is closely related to risk of greater exposure to infectious diseases. Theoretically grounded studies of tourist biosecurity behavior and tr

Debatten om covid-19 fokuserar främst på medicinska områden som smittspridning, antikroppar och vacciner. Men det finns andra aspekter som glöms bort.Våren 2020 rapporterade Interpol att stora mängder förfalskade covid-19- skyddsprodukter av olika slag var i omlopp. Nu ett år senare har den globala illegala spridningen ökat. Det gäller allt från undermåliga ansiktsmasker till sådant som utger sig

Sizeable number of stellar-mass black holes (BHs) in globular clusters (GCs) can strongly influence the dynamical evolution and observational properties of their host cluster. Using results from a large set of numerical simulations, we identify the key ingredients needed to sustain a sizeable population of BHs in GCs up to a Hubble time. We find that while BH natal kick prescriptions are essential

We have been investigating populations of cataclysmic variables (CVs) in a set of more than 300 globular cluster (GC) models evolved with themoccacode.[-120pt] One of the main questions we have intended to answer is whether most CVs in GCs are dynamically formed or not. Contrary to what has been argued for a long time, we found that dynamical destruction of primordial CV progenitors is much strong

This paper presents and discusses a recently digitized, dataset of strikes and lockouts in Sweden for the period 1859-1902. The dataset, which originally was collected by Axel Raphael by retrospectively browsing through newspapers, pre-dates the Swedish official statistics on work stoppages that began in 1903. Whereas Raphael’s data have been used to illustrate the long-run development of strikes,

This paper discusses which freehand drawing skills a designer needs in the 21st century and why not more people are using sketching as a creative tool. Are design schools teaching the adequate skills needed today? In the past 5-10 years focus has shifted from product design to experience design and the skills needed to make high end drawings might not be needed to the same extent. 3D computational