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Short fatigue cracks are known to have a growth behaviour different from that of long cracks, the latter well predicted by linear elastic fracture mechanics. Short cracks can grow at high rates at load levels well below the threshold value for long cracks, before entering into the long crack region, or arrest and become nonpropagating cracks. The growth behaviour of short cracks is strongly influe

Chromosomal aneuploidy, that is, numerical chromosome aberrations, is one of the molecular hallmarks of cancer. However, when neoplasms are studied with sequencing- and array-based approaches, chromosome numbers and ploidy states are typically inferred from bulk DNA data. Furthermore, published molecular estimates of neoplasia-associated aneuploidy often also include genomic imbalances resulting f

Violence against women (“VAW”) is a global matter; and human rights law-inspired approaches, also universal in nature (it is argued), can be the missing link in tackling a global problem. In underlining the universal applicability of human rights standards, principles and norms; it is suggested that drawing inspiration from human rights-based approaches would contribute to implementation of holist

This thesis addresses the issue of customer relationship building in new small retail ventures with a particular focus on individual consumers and application of such relationship marketing concepts as trust, satisfaction, loyalty and value. This research rests upon a qualitative single-case study of a new German retail venture and assumes an interpretivist approach. The main method of inquiry enc

Arbetets syfte är att belysa hur en effektiv överlämning av stora projekt från entreprenad till drift och underhåll går till. Syftet är också att undersöka vilka nyckelfaktorer som skapar framgång och motgång i denna fas av projektet Frågeställning i studien är: Hur görs en effektiv överlämning av ett stort projekt? Vilka faktorer skapar framgång tillika motgång för projektets överlämning? Varför The purpose of the study is to illustrate how a efficient handover is done in mega project between the constructional and operational phases. Furthermore the purpose is the study what key factors lead to success and failure throughout the handover. The objective of the study is to answer the following questions: How is an efficient handover done? What factors lead to success and failure in mega pr

Fastän folkrätten ibland kallas den globala rättsordningen, betraktas dess olika discipliner ofta enskilt. Det är därför intressant att undersöka förhållandena mellan disciplinerna, eftersom det är svårt att hävda att folkrätten är ett enskilt rättsområde om de är alltför avlägsna varandra. Syftet med detta examensarbete är därför att ge ett exempel som grund för framtida diskussioner om de inbördAlthough public international law is sometimes referred to as the global legal order, its various disciplines are often considered in isolation. It is therefore interesting to investigate the relationships between the disciplines, because if they are too distant, it may be hard to claim that public international law is a single legal order. The purpose of this thesis is therefore to provide an exa

Sverige är ett av världens ledande länder när det gäller export av krigsmateriel, och exporterar till såväl demokratier som icke-demokratier. Denna uppsats ämnar undersöka hur Sveriges export av krigsmateriel är förenlig med landets åtaganden för bevarandet och skyddandet av de mänskliga rättigheterna på den internationella arenan genom att studera exporten till Förenade Arabemiraten, Norge och US

This chapter argues for a new listening practice for electroacoustic music (EAM) that I call “deep situated listening”. “Deep situated listening” builds on existing EAM-theories, aesthetics and practices – which I here collectively refer to as the “hearing heads” approach – but extends this approach by adding an explicitly feminist perspective. “Deep situated listening” combines Donna Haraway’s no

Infections due to the opportunistic fungus Candida have been on the rise in the last decades, especially in immunocompromised individuals and hospital settings. Unfortunately, the treatments available today are limited. Thrombin-derived C-terminal peptide (TCP-25) is an antimicrobial peptide (AMP) with antibacterial and immunomodulatory effects. In this work, we, for the first time, demonstrate th

The two-dimensional (2D) affinity between protein molecules across contacting cells is a key parameter regulating and initiating several cellular processes. However, measuring 2D affinity can be challenging, and experimental data are limited. In addition, the obtained 2D affinities are typically averaged over the cell population. We here present a method to measure 2D affinity on single cells bind

This review aims to provide a comprehensive overview of the in vitro, animal, and clinical studies with the bacterial strain Lactiplantibacillus plantarum 299v (L. plantarum 299v; formerly named Lactobacillus plantarum 299v) published up until June 30, 2020. L. plantarum 299v is the most documented L. plantarum strain in the world, described in over 170 scientific publications out of which more th

This paper reviews the current literature regarding iron oxide formation in the wheel-rail contact in order to assess the possible role of iron oxides in the “Wet-Rail” phenomenon, which causes low adhesion between the wheel and the rail. The paper discusses the structure and formation of oxides from a chemical perspective before analysing the direct tribological effects and outlining the techniqu

The morphology of gas-rich disc galaxies at redshift ∼ 1–3 is dominated by a few massive clumps. The process of formation or assembly of these clumps and their relation to molecular clouds in contemporary spiral galaxies are still unknown. Using simulations of isolated disc galaxies, we study how the structure of the interstellar medium and the stability regime of the discs change when varying the

BACKGROUND: Our aim was to investigate the prognostic potential of circulating dipeptidyl peptidase 3 (cDPP3) to predict mortality and development of organ dysfunction in a mixed intensive care unit (ICU) population, and for this reason, we analysed prospectively collected admission blood samples from adult ICU patients at four Swedish hospitals. Blood samples were stored in a biobank for later ba

In contrast to the other chapters in Part V, Nina Wilén’s focus is on multilateral military interventions at the regional level: She explores the relationship between sovereignty, intervention, and the international normative order, by examining how ECOWAS, an African regional organization, justified its intervention in Liberia’s civil war referring to international norms. Based on a critical disc

The paper presents a systematic examination of data from two early math interventions, involving 188 children aged 3,5-6,5 and their teachers. The aim is to cast light on how a digital early math game can be spontaneously extended into the physical environment by children and by teachers. Questions were: i) how the math content was extended to the physical room, ii) which elements of the game and

Activation of AMP-activated protein kinase (AMPK) is considered a valid strategy for the treatment of type 2 diabetes. However, despite the importance of adipose tissue for whole-body energy homeostasis, the effect of AMPK activation in adipocytes has only been studied to a limited extent and mainly with the AMP-mimetic 5-aminoimidazole-4-carboxamide-1-b-d-ribofuranoside (AICAR), which has limited