Filtyp
Symptomatic venous thromboembolism (VTE) occurs in five percent of children treated for acute lymphoblastic leukemia (ALL), but whether a genetic predisposition exists across different ALL treatment regimens has not been well studied. Methods: We undertook a genome-wide association study (GWAS) meta-analysis for VTE in consecutively treated children in the Nordic/Baltic acute lymphoblastic leukemi
Background: Early diagnosis of mild lymphedema and treatment are important to prevent its progress. The tissue dielectric constant (TDC), measuring local tissue water in the skin and upper subcutis, has neither been related to the water displacement method (WDM) nor been used to diagnose mild arm lymphedema in patients at risk. Our aims were to evaluate TDC and WDM in combination with palpation, e
(“Dissolved organic carbon leaching flux in a mixed agriculture and forest watershed in Rwanda” [1]). This article presents data of leached dissolved organic carbon (LDOC), stream water dissolved organic carbon), rainfall amount (Ra), rainfall intensity (Ri), rainfall soil storage (S), runoff (Q), and soil properties such as total organic carbon (TOC), total nitrogen (TN), cation exchange capacity
A software prototype is developed for assessing and updating the reliability of single-cell prestressed concrete box girders subjected to chloride-induced reinforcement corrosion. The underlying system model consists of two integrated sub-models: a condition model for predicting the deterioration state of the box girder and a structural model for evaluating the overall system reliability. The cond
OBJECTIVE: This study explored the association of patients' demographics, health status, symptom severity, previous osteoarthritis (OA) care, and psychological status with the change in pain severity following a first-line intervention including education and exercise for OA provided nationwide in Swedish primary care. METHODS: This register-based cohort study included 23,309 people with knee or h
Background: User involvement is a requirement of most research funders. There is a growing body of literature exploring the benefits and challenges of user involvement in research, but such studies are scarce in the field of aging and health. Moreover, the majority of such research is qualitative, which limits the generalizability of results. The UserAge panel study will be instrumental in expandi
Precision-cut lung slices (PCLS) have gained increasing interest as a model to study lung biology/disease and screening novel therapeutics. In particular, PCLS derived from human tissue can better recapitulate some aspects of lung biology/disease as compared to animal models. Several experimental readouts have been established for use with PCLS, but obtaining high yield and quality RNA for downstr
The demand for better methods for condition control and monitoring of embankment dams will increase in a near future as a result of expected more extreme weather situations. Furthermore the availability demand on hydropower will increase as a result of switching from fossil fuels to wind and solar power, in some countries in combination with decommissioning of nuclear power. Temperature monitoring
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This thesis provides an insight into Jamaica’s energy situation and its electricity sector through the barriers that prevent the implementation of renewable energy. In both the energy sector and electricity sub-sector the need to incorporate alternative energy sources, it has revealed, is becoming more apparent with increasing oil prices, widening debt burdens and rising unemployment, among others
This researchʼs foundation is the current state of affairs in Kiribati in relation to the effects of climate change and how the nation will face the future. The paper examines how different actors in Kiribati are helping the country prepare for possible climate change displacement in the future, from the viewpoint of said actors. Interview data, supplemented by observational data from time spent i
I rapporten undersöks hur kommuner och regioner kan stärka sin ledningsförmåga – det vill säga förmågan att samordna beslutskraft och handlingskraft – i en tid präglad av komplexa samhällsutmaningar, begränsade resurser och höga krav på legitimitet och effektivitet. Rapporten baseras på intervjuer med ledande politiker och tjänstepersoner i åtta kommuner och tre regioner. Rapportens utgångspunkt ä
Upptakten till krisen utspelade sig i Argentina under 1880 talet. Landet hade efter inre oroligheter stabiliserats och i likheter med Sverige ett decennium tidigare fått ökade exportintäkter efter ökad efterfrågan på råvaror som landet exporterade. Med guldstandardens internationella etablering och större kapitalflöden över gränserna blev stora kapitalsatsningar i Argentina möjliga. Tidigare britt
This thesis examines how the European Union’s recent development towards binding regulations on Human Rights Due Diligence and Environmental, Social, and Governance (ESG) disclosure, particularly the Corporate Sustainability Due Diligence Directive and Corporate Sustainability Reporting Directive have impact on Chinese companies and China’s regulatory framework. These laws require companies to ide
With the expected further electrification of society, a greater electricity demand is to be expected, requiring improved flexibility. One proposal that meets these demands is the adaptation of the current district heating power plants by adding condensing tail turbines. Condensing tail turbines allow for further expansion of steam. A simple economic analysis showed that implementing a condensing t
Background: Extended reality (XR), encompassing technologies such as virtual reality, augmented reality, and mixed reality, has rapidly gained prominence in health care. However, existing XR research often lacks rigor, proper controls, and standardization. Objective: To address this and to enhance the transparency and quality of reporting in early-phase clinical evaluations of XR applications, we
BACKGROUND: Leukocytes have been reported to have tumor stimulating effects in colorectal cancer, among other malignancies. In line with this, earlier research has shown improved disease-free survival in patients with postoperative neutropenia compared to non-neutropenic patients following cytoreductive surgery (CRS) and hypertherm intraperitoneal chemotherapy (HIPEC).AIM: To evaluate the impact o
Precision-cut lung slices (PCLS) have gained increasing interest as a model to study lung biology and disease, as well as for screening novel therapeutics. In particular, PCLS derived from human tissue can better recapitulate some aspects of lung biology and disease as compared to PCLS derived from animals (e.g. clinical heterogeneity), but access to human tissue is limited. A number of different
