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It has been proposed that hyaluronan-binding proteoglycans play an important role as guiding cues during neural crest (NC) cell migration, but their precise function has not been elucidated. In this study, we examine the distribution, structure and putative role of the two major hyaluronan-binding proteoglycans, PG-M/versicans and aggrecan, during the course of avian NC development. PG-M/versicans

Several findings link proteinase 3 (PR3) to small vessel vasculitis. Besides being a major target of anti-neutrophil cytoplasm antibodies (ANCA), previous findings have shown increased circulating levels of PR3 in vasculitis patients, increased levels of neutrophil membrane-PR3 (mPR3) expression and a skewed distribution of the − 564 A/G polymorphism in the promotor region of the PR3 gene. In this

Cigarette smoke exposure is well known to cause cardiovascular and airway diseases, both of which are leading causes of death and disability in the world. However, the molecular mechanisms that link cigarette smoke to cardiovascular and airway diseases are not fully understood. Vascular and airway hyper-reactivity plays an important role in the pathogenesis of cardiovascular and airway diseases. R

This book chapter examines the rapidly expansion of various neospiritual and science-like practices currently mobilized in late modern Swedish pursuits of identity, meaning, and health. The focus is on the emergence and marketing of new entrepreneurs who have established themselves as “therapists” or “coaches”, promoting personal development, and how they organize their own systems of training and

Book abstract: The book reviews recent observations of non-evolved and evolved binary populations in clusters and the field with special emphasis on statistical biases, incompleteness and distribution functions. Different binary types are considered: cataclysmic variables, super-soft X-ray sources, double degenerate binaries, Algol-type binaries, Be binaries, X-ray binaries, and Wolf-Rayet binarie

Quantitative magnetic resonance imaging (MRI)-based biomarkers, which capture physiological and functional tumor processes, were evaluated as imaging surrogates of early tumor response following chemoradiotherapy in glioma patients. A multiparametric extension of a voxel-based analysis, referred as the parametric response map (PRM), was applied to quantitative MRI maps to test the predictive poten

Type 1 diabetes involves the specific destruction of the pancreatic islet β-cells, eventually resulting in a complete dependency of exogenous insulin. The clinical onset of diabetes is preceded by the appearance of autoantibodies against β-cell antigens. The human leukocyte antigen (HLA) region is the single most important genetic determinant of Type 1 diabetes susceptibility, yet variability in t

This paper explores the bearing had by Aymara notions of spirit loss on contemporary indigenous discourses of colonialism and decolonization and discusses the dynamics of cross-fertilization between “traditional” curing practices and cosmology on the one hand and indigenous ethnopolitical activism and discourse on the other.

Mysticism can be regarded as an integral element of religion. It includes both a way of life and a direct consciousness of the presence of God. Broadly defined as such, one can encounter mystical dimensions within all religions of the world. In order to alter consciousness, mystics in different traditions use a variety of techniques – different types of meditation, visualisation, repetitive prayer

An improved nonlinear asymptotic theory of spiral density waves is developed. It extends the theory developed by Yuan & Kuo to a global theory, not just one limited to the vicinity of the resonance. It can then be applied to the recent high-resolution observations of CO and HST NICMOS of nearby spiral galaxies. As an example, we apply the theory to the nearby grand-design spiral galaxy NGC 524

We present the first results from several ongoing studies of the stellara bundances, ages, and chemical trends in the long-lived dwarf stars in the solar neighborhood that belong to the thin and thick galactic disk.We confirm that the trends of α-elements in the thin and thick disk are distinct, and we also find that the thick disk show the typical signature of SN Ia contribution to the chemical e

The relationship between the frequency of River Ammer floods (southern Germany) and atmospheric circulation variability is investigated based on observational Ammer River discharge data back to 1926 and a flood layer time series from varved sediments of the downstream Lake Ammer for the pre-instrumental period back to 1766. A composite analysis reveals that, at synoptic timescales, observed River

Since EU’s expansion to incorporate former Communist countries, attempts to solve the so-called “Roma issue” spurred an unprecedented array of policies, interventions and measures at national and transnational level. Instead of the expected positive changes, discrimination and poverty worsened. The current migration waves, economic crisis, and the surge of far-right nationalism, contributed to an

Ett varumärkesrättsligt skydd är ofta något som företag arbetar hårt för att uppnå. I vissa fall kan ett varumärke anses ha ett ekonomiskt värde i sig. Den tekniska utvecklingen har medfört ett förändrat samhällsklimat där individer getts ett allt större utrymme att utrycka sig. Ett förhållandevis nytt fenomen är influencers – personer som via internetplattformar använder sin egen person för att mA trademark protection is often something that companies work hard for. In some cases, a trademark may be considered to have an economic value in itself. The technological development has led to a changed social climate in which individuals are given an increasing amount of space to express themselves. A relatively new phenomenon is influencers – people who, via internet platforms, use their own p

There has been little empirical study of the relationship between remittance inflows and economic growth, especially with a focus in Asia and the Pacific (APAC) region. In this paper, this relationship for 23 APAC economies is examined. A panel data set of remittances and financial development indices for the period 1990 – 2017 is set up to explore the impact of financial development on remittance