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Towards the Era of Mixed Reality: Accessibility Meets Three Waves of HCI

Today, the underlying theoretical and methodological foundations as well as implementations in the field of accessibility are largely based on plans, metrics and heuristics. There is an obvious tension between these norms and those of the overall spirit of the times, which leans heavily towards improvisations, diversity, and ever-changing affordances. The parallel evolution of human computer inter

Cdc42/N-WASP signaling links actin dynamics to pancreatic β cell delamination and differentiation.

Delamination plays a pivotal role during normal development and cancer. Previous work has demonstrated that delamination and epithelial cell movement within the plane of an epithelium are associated with a change in cellular phenotype. However, how this positional change is linked to differentiation remains unknown. Using the developing mouse pancreas as a model system, we show that β cell delamin

Copeptin relates to a fatty liver and measures of obesity in a South African population with mixed ethnicities

Purpose: Elevated copeptin, a vasopressin marker, is linked to metabolic disease, and obese rats with low-vasopressin concentration had a decreased risk of liver steatosis. We here investigated the association between copeptin and nonalcoholic fatty liver disease (NAFLD) and possible differences in copeptin concentration between ethnicities. Methods: In this cross-sectional study of 361 South Afri

Fission dynamics with microscopic level densities

Working within the Langevin framework of nuclear shape dynamics, we study the dependence of the evolution on the degree of excitation. As the excitation energy of the fissioning system is increased, the pairing correlations and the shell effects diminish and the effective potential-energy surface becomes ever more liquid-drop like. This feature can be included in the treatment in a formally well-f

Constructing social identity through multiple "us and them" : a grounded theory study of how contextual factors are manifested in the lives of residents of a vulnerable district in Brazil

The association between contextual factors and health inequalities is well documented, also in Brazil. However, questions about how contextual factors actually affect health and well-being persist. The aim of this qualitative study was to explore how contextual factors-i.e., social stratification and neighborhood opportunity structures-are manifested in the lives of the residents of a vulnerable d

Open-access portal with hindcast wave data for Skåne and Halland

Wave climate data for the Swedish provinces Skane and Halland, were hindcast using SWAN, a third-generation spectral wave model. The 40-year wave dataset, from 1979 to 2019, is made available through an open-access data portal (https://gis.sgi.se/vagmodell/). The wave data has a three-hour resolution and includes significant wave height, peak wave period, and wave direction. The wave model domain

Anxiety reduction through obstetric consultation combined with ultrasound examination in women after cesarean section

Background: Women are at increased risk of developing anxiety or depression disorders after Cesarean section (CS). This study aims to evaluate whether an appointment with a senior obstetrician combined with an ultrasound examination reduces levels of anxiety in women after CS. Methods: A prospective observational study was conducted in Sweden. Women underwent an appointment with an obstetrician 6–

Energy use and carbon emissions: From decoupling and transitions to sufficiency?

The paper examines and illustrates different trends in relation to historical energy use-related intensities and corresponding CO2 emission trends. The methodology encompasses a decomposition quantitative approach for estimating decoupling trends to energy use and economic and demographic parameters driving CO2 emission levels. The analysis covers both global and regional trends for the period 197

Vice in the Service of Virtue: John Cleland's Memoirs of a Woman of Pleasure

Originally published in two volumes in 1748-9, John Cleland’s Memoirs of a Woman of Pleasure (or Fanny Hill) has long been an underground classic. Because of this underground status, and the prejudicial treatment of literary pornography, Memoirs has never been thoroughly investigated. Above all, insufficient attention has been given to the educational and moral aspects of Cleland’s novel. Cleland’