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Purpose: When a child needs a hematopoietic stem cell transplant, the seriousness of the child's illness is highlighted. The purpose of this study was to explore parents' experiences of the transplantation process when two children in the family are involved, one severely ill child as the recipient and the other as the donor. Methods: In this qualitative study, interviews were conducted with 18 pa
The aggregating proteoglycans (aggrecan, versican, neurocan, and brevican) are important components of many extracellular matrices. Their N-terminal globular domain binds to hyaluronan, but the function of their C-terminal region containing a C-type lectin domain is less clear. We now report that a 90-kDa protein copurifies with recombinant lectin domains from aggrecan and versican, but not from t
During amino acid starvation the Escherichia coli stringent response factor RelA recognizes deacylated tRNA in the ribosomal A-site. This interaction activates RelA-mediated synthesis of alarmone nucleotides pppGpp and ppGpp, collectively referred to as (p)ppGpp. These two alarmones are synthesized by addition of a pyrophosphate moiety to the 3 position of the abundant cellular nucleotide GTP and
The apparition of adaptive immunity in Gnathostomata correlates with the expansion of the E-protein family to encompass E2-2, HEB, and E2A. Within the family, E2-2 and HEB are more closely evolutionarily related but their concerted action in hematopoiesis remains to be explored. Here we show that the combined disruption of E2-2 and HEB results in failure to express the early lymphoid program in Co
Due to social and environmental crises, the concept of sustainability has grown in importance in our society over the past years. Things are changing, even in the financial industry. From the perspective of investors, the general public, and enterprises, Corporate Social Responsibility and the creation of sustainable value are becoming more and more significant. One of the most cutting-edge tools
Local commercial fishing is often claimed to attract tourists to coastal communities. We investigate the impact of local fishing on tourism demand, measured as overnight stays, in Sweden. Using municipal-level data for the period 1998–2015, we perform a quantitative analysis using ordinary least squares (OLS) as well as panel-data methods that take unobserved heterogeneity between municipalities i
Previous research on variation in patient reported experience measures (PREMs) suggest that it is important to be cautious when using comparative information about patients’ experiences, collected via patient surveys, to assess provider performance. Not all factors associated with variation in PREMs are related to factors that providers themselves can control. This study explores if structural cha
High levels of nitrogen (N) deposition might result in a transition from N to phosphorus (P) limitation in high latitude forests. Thiscould have fundamental consequences for forest production, nutrient acquisition and nutrient leaching.I studied a Norway spruce forest in a region of high N deposition in southwest Sweden and added N, P or N+P to force thesystem to N or P limitation. I studied tree
Predicting live birth after the first IVF/ICSI treatment is challenging, as many factors may interact to affect IVF/ICSI outcomes. Adenomyosis is one factor that impacts live birth rates. Machine learning algorithms have been shown valuable for detecting complex dependencies and predicting outcomes in different clinical settings. We aimed to develop a prediction model for live birth after IVF/ICSI
The focus of this study was exploring the product development process of a dairy- based drink which was co-created within a public-private partnership approach for Base of Pyramid (BoP) consumers in Zambia. An exploratory case-study research design was selected. Through interviews, documentation and observations, the steps of the product development process were mapped and the contributions from t
MILJÖVETENSKAP Preliminärt schema 2019-10-02 Kurs: MVEN16 Klimatpolitik, samhällsstyrning och kommunikation, HT19 Kursansvarig: RH: Roger Hildingsson, Statsvetenskapliga inst; roger.hildingsson@svet.lu.se Lärare: CD: Carl Dalhammar, IIIEE; carl.dalhammar@iiiee.lu.se JAO: Johanna Alkan Olsson, CEC/Miljövetenskap; johanna.alkan_olsson@cec.lu.se JK: Jamil Khan, Miljö- och energisystemanalys, LTH; jam
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mven16_schema_ht19_prel.pdf - 2026-07-22
BackgroundSexual violence is widespread in the eastern parts of the Democratic Republic of the Congo, including in the North Kivu province. Moreover, in this region survivors of sexual violence often have limited access to care and encounter a variety of barriers when seeking care and support. The aim of this study was to explore community perceptions about access to care, barriers, enablers and p
