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"Was mich nicht umbringt macht mich stärker" Polisen & PTG

Syftet med studien var att undersöka om poliser som exponerats för hot och våld i yrket hade en högre grad av Posttraumatic Growth, PTG. Studien fokuserade på att mäta PTG i relation till hot och våld på följande parametrar; psykologisk hantering, reaktioner i form av hur rädda de kände sig i dag och psykisk påverkan. Respondenterna var 42 poliser från Skåneregionen. Åldrarna varierade från 26 tilThe purpose of this study was to investigate whether police officers who have been exposed to threats and violence in their profession have a higher degree of Posttraumatic Growth, PTG. PTG was measured in relation to threats and violence on the following parameters; psychological management, reactions which included current feelings of threat/anxiety and psychological influence. The respondents i

Iscensätta barnperspektiv : Före, under och efter Barnahusbesök

Barnahus syftar till att förbättra utredningar och samarbete mellan myndigheter när barn misstänks ha varit utsatta för brott som misshandel eller sexuella övergrepp. I Barnahus samverkar olika instanser som socialtjänst, polis, åklagare, barnmedicin, rättsmedicin samt barn- och ungdomspsykiatri i en barnvänlig miljö. I stället för att behöva upprepa sin berättelse för olika tjänstemän på olika plBarnahus in Sweden exist to improve investigations and the collaboration between public agencies when children are suspected being victims of physical and/or sexual abuse. Barnahus are multi-agency collaborations that bring together local authority child welfare services, the police, public prosecutors, paediatric medicine, forensic medicine, and child- and adolescent psychiatry in a child-friendl

Surveillance of COVID-19 vaccine effectiveness : A real-time case-control study in southern Sweden

The extensive register infrastructure available for coronavirus disease 2019 surveillance in Scania county, Sweden, makes it possible to classify individual cases with respect to hospitalisation and disease severity, stratify on time since last dose and demographic factors, account for prior infection and extract data for population controls automatically. In the present study, we developed a case

Dissection of progenitor compartments resolves developmental trajectories in B-lymphopoiesis

To understand the developmental trajectories in early lymphocyte differentiation, we identified differentially expressed surface markers on lineage-negative lymphoid progenitors (LPs). Single-cell polymerase chain reaction experiments allowed us to link surface marker expression to that of lineage-associated transcription factors (TFs) and identify GFRA2 and BST1 as markers of early B cells. Funct

A novel method for creatinine adjustment makes the revised Lund–Malmö GFR estimating equation applicable in children

The aim of this study was to establish creatinine growth curves separately for males and females that can be used to adjust childhood levels of serum creatinine to corresponding adult levels. Linear regression with fractional polynomials of age as independent variable was used to construct creatinine growth curves for a reference cohort (n = 83,157 samples from Belgium and Sweden, age 2–40 years).

Current evidence of oral anticoagulant reversal : A systematic review

Introduction Approximately 4–6% of patients treated with oral anticoagulants (OAC) will suffer from major hemorrhage or be in need of urgent surgery necessitating anticoagulant reversal therapy. Several new oral anticoagulants and reversal agents have been introduced that make it difficult for physicians to stay updated on the current evidence of reversal management. This study aims to review the

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This work presents a case where a combination of electromagnetics (EM61), refraction seismic surveys and a geotechnical survey allowed a detailed mapping of the near surface at a soil depot. Such results together with knowledge of the glacial overburden and groundwater potential enabled accurate determination of digging depth within the area, and thereby optimizing extension of the soil depot. The

Investigating the causal relationships between excess adiposity and cardiometabolic health in men and women

AIMS/HYPOTHESIS: Excess adiposity is differentially associated with increased risk of cardiometabolic disease in men and women, according to observational studies. Causal inference studies largely assume a linear relationship between BMI and cardiometabolic outcomes, which may not be the case. In this study, we investigated the shapes of the causal relationships between BMI and cardiometabolic dis

Perinatal risk factors for developmental coordination disorder in children born extremely preterm

Aim: Children born extremely preterm frequently have developmental coordination disorder (DCD). We aimed to evaluate perinatal risk factors for DCD. Methods: Swedish national cohort study including 226 children born before 27 gestational weeks without major neurodevelopmental disabilities at 6.5 years. Outcome was DCD, defined as ≤5th percentile on the Movement Assessment Battery for Children-Seco

Pulmonary Hypertension Phenotype Can Be Identified in Heart Failure With Reduced Ejection Fraction Using Echocardiographic Assessment of Pulmonary Artery Pressure With Supportive Use of Pressure Reflection Variables

Background: Pulmonary hypertension (PH) is frequent in patients with heart failure and reduced ejection fraction (HFrEF) with 2 different phenotypes: isolated postcapillary PH (IpcPH) and, with the worst prognosis, combined pre- and postcapillary PH (CpcPH). The aims of the present echocardiography study were to investigate (1) the ability to identify PH phenotype in patients with HFrEF using the

Policy brief: Paleoklimatet informerar oss om framtiden

Paleoklimatologi – läran om hur klimatet utvecklats genom jordens historia – ger oss referensramar för att sätta dagens klimat och möjliga framtida klimatförändringar i ett historiskt perspektiv. Till exempel visar nya analyser av historiska klimatarkiv att för norra halvklotet var perioden 1983-2012 sannolikt den varmaste på 1400 år. Vi ser även att vid den senaste värmeperioden, för 125 000 år s

Pilot RCT of the Attempted Suicide Short Intervention Program (ASSIP) adapted for rapid delivery during hospitalization to adult suicide attempt patients with substance use problems

Objective: The Attempted Suicide Short Intervention Program (ASSIP) was adapted for hospital delivery and to address substance use problems as well as evaluated for feasibility, acceptability, and therapist fidelity in a series of preparatory steps (n = 28) and in a pilot randomized controlled trial, RCT (n = 34). Method: In the RCT, patients with suicide attempts and substance use problem(s) with

Preoperative prognostic factors associated with early mortality after upfront pancreatoduodenectomy for Pancreatic Adenocarcinoma

Introduction: Tumour related factors are well known as risk factors for survival after pancreatoduodenectomy (PD). In a time when the role for neoadjuvant treatment is discussed also in primary resectable patients, the influence of preoperative variables is of interest. The aim was to examine preoperative factors influence on early mortality following PD.Materials: Patients registered in the Swedi

Increased genetic marker density reveals high levels of admixture between red deer and introduced Japanese sika in Kintyre, Scotland

Hybridization is a natural process at species range boundaries, but increasing numbers of species are hybridizing due to direct or indirect human activities. In such cases of anthropogenic hybridization, subsequent introgression can threaten the survival of native species. To date, many such systems have been studied with too few genetic markers to assess the level of threat resulting from advance

Tertiary lymphoid structures improve immunotherapy and survival in melanoma

Checkpoint blockade therapies that reactivate tumour-associated T cells can induce durable tumour control and result in the long-term survival of patients with advanced cancers1. Current predictive biomarkers for therapy response include high levels of intratumour immunological activity, a high tumour mutational burden and specific characteristics of the gut microbiota2,3. Although the role of T c

Regulation of fungal decomposition at single-cell level

Filamentous fungi play a key role as decomposers in Earth’s nutrient cycles. In soils, substrates are heterogeneously distributed in microenvironments. Hence, individual hyphae of a mycelium may experience very different environmental conditions simultaneously. In the current work, we investigated how fungi cope with local environmental variations at single-cell level. We developed a method based

Vibrational wavepacket dynamics in Fe carbene photosensitizer determined with femtosecond X-ray emission and scattering

The non-equilibrium dynamics of electrons and nuclei govern the function of photoactive materials. Disentangling these dynamics remains a critical goal for understanding photoactive materials. Here we investigate the photoinduced dynamics of the [Fe(bmip)2]2+ photosensitizer, where bmip = 2,6-bis(3-methyl-imidazole-1-ylidine)-pyridine, with simultaneous femtosecond-resolution Fe Kα and Kβ X-ray em

Comment on 'AIRE-deficient patients harbor unique high-affinity disease-ameliorating autoantibodies'

The AIRE gene plays a key role in the development of central immune tolerance by promoting thymic presentation of tissue-specific molecules. Patients with AIRE-deficiency develop multiple autoimmune manifestations and display autoantibodies against the affected tissues. In 2016 it was reported that: i) the spectrum of autoantibodies in patients with AIRE-deficiency is much broader than previously

Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine

Precision medicine is part of the logical evolution of contemporary evidence-based medicine that seeks to reduce errors and optimize outcomes when making medical decisions and health recommendations. Diabetes affects hundreds of millions of people worldwide, many of whom will develop life-threatening complications and die prematurely. Precision medicine can potentially address this enormous proble