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Cellobiose dehydrogenase hosted in lipidic cubic phase to improve catalytic activity and stability

Lipidic cubic phase systems (LCPs) are excellent carriers for immobilized enzymes due to their biocompatibility and well-defined nanoporous structure. Lipidic cubic phases act as a convenient matrix to incorporate enzymes and hold them in the vicinity of electrode surfaces in their fully active forms. Corynascus thermophilus cellobiose dehydrogenase (CtCDH) was trapped in a monoolein cubic phase,

Cholera Vaccine Use Is Associated With a Reduced Risk of Death in Patients With Colorectal Cancer : A Population-Based Study

Background & Aims Cholera toxin can act as a modulator of the immune response with anti-inflammatory effects; it reduces development of colon polyps in mouse models of colorectal cancer (CRC). We performed a population-based study to determine whether, in patients with a diagnosis of CRC, subsequent administration of the cholera vaccine (killed Vibrio cholerae O1 whole cells and recombinant ch

Incidence and familial risk of pleural mesothelioma in Sweden : A national cohort study

Familial clustering of pleural mesothelioma was reported previously, but none of the reports quantified the familial risk of mesothelioma or the association with other cancers. The contributions of shared environmental or genetic factors to the aggregation of mesothelioma were unknown. We used a number of Swedish registers, including the Swedish Multigeneration Register and the Swedish Cancer Regi

Association of family history of type 2 diabetes with prostate cancer : A national cohort study

Background: Personal history of type 2 diabetes mellitus (T2DM) is associated with a lower incidence of prostate cancer, but the underlying mechanisms are largely unknown. We hypothesized that genetic factors that are involved in the development of T2DM might protect against prostate cancer. Methods: We used a few Swedish registers, including the Swedish Multigeneration Register and the Cancer Reg

Risk of solid tumors and hematological malignancy in persons with Turner and Klinefelter syndromes : A national cohort study

The risk of solid and hematological malignancy in patients with Turner syndrome, characterized by X chromosome monosomy in women, and Klinefelter syndrome, characterized with two and more X chromosomes in men, is not well established, but such evidence may have etiological implications on cancer development. We identified a total of 1,409 women with Turner syndrome and 1,085 men with Klinefelter s

Equipped for resistance : an agonistic conceptualisation of the public library as a verb

A theoretical framework for understanding public library development is presented; plural agonistics is used in combination with an approach inspired by post-humanism. The framework is related to examples from a study of two Swedish public libraries. Antagonism is viewed as foundational, and democracy as an ongoing process, the task being to transform antagonism to agonism, with institutions like

Cancer risk in patients with hepatitis C virus infection : A population-based study in Sweden

Increased risks of certain cancers have been observed in patients with hepatitis C virus (HCV) infection. However, data on other cancer sites/types are lacking. We analyzed systematically the risk of developing 35 common cancers in patients with HCV infection using a nationwide Swedish database. Patients with HCV infection were identified from the Swedish Hospital Inpatient and Outpatient Register

Age-Dependent Metastatic Spread and Survival : Cancer of Unknown Primary as a Model

In order to describe a novel approach for the clinical study of metastases, we provide here age-specific incidence and survival data for cancer of unknown primary (CUP). Metastases in various organs are found at CUP diagnosis, which have implications for prognosis, and we hypothesize similar prognostic implications for metastases found at diagnosis of primary cancers. We identified 33,224 CUP pati

Whisky is for drinking; Water is for fighting over : a critical investigation of the decision to build the Broken Hill Pipeline

Water is a necessity for human survival, and a lack of sufficient clean water can have severe negative impacts on human health, economic activity, food security and societal relations. Increasing demand on water resources around the globe often leads to conflicts between different water users who compete for available supplies. The Murray Darling Basin (MDB) in Australia is an area that faces many

We are Elites and Losers : Constructing Community Identity and Seeking Social Capital in an Online Subcultural Group in China

This thesis focuses on the combination of youth subculture and online community in the contemporary Chinese context. It aims to explore the characteristics of the Chinese online youth subculture and how members construct their collective identities and gain alternative social capital in an online subcultural group. To exert the power of a good example as Flyvbjerg (2001) emphasizes, this thesis ch

Personligt betalningsansvar vid kritisk kapitalbrist

Det är en grundidé i aktiebolagslagen att bolagsformen i stor utsträckning skall utgöra en riskbegränsad form av företagande. Det finns dock situationer där denna idé frångås och fysiska personer blir ansvariga för bolagets skulder. Uppsatsen skall utreda sådana situationer i anslutning till ABL:s regler om kritisk kapitalbrist. Reglerna riktar till stor del in sig på styrelsen och dennes agerandeIt’s one of the basic ideas Swedish Companies Act (SCA) that limited liability company is supposed to be a risk-limited form of business for owners, board members and other company officials. There are however situations when this idea is put aside in favour for other interests and board members can be personally responsible for the company’s debts. This essay will investigate such situations in c

Förändringsfaktorer under exponering och responsprevention för OCD: betydelsen av motivation, följsamhet och självförmåga

Trots att exponering- och responsprevention (ERP) är en effektiv behandling för patienter med tvångssyndrom (eng: obsessive-compulsive disorder; OCD), blir inte alla hjälpta. Medan många författare har intresserat sig för demografiska och kliniska faktorers betydelse för behandlingsutfall, är det få studier som har undersökt hur processer som uppstår under behandling (t.ex. förändring i motivationExposure and response prevention (ERP) is an effective treatment for obsessive-compulsive disorder (OCD), but not everyone benefits. While many authors have explored the contribution of demographic and clinical factors in relation to treatment outcome, few studies have investigated how processes that occur during the course of treatment (e.g., changes in motivation) relate to treatment outcome. Th

Data-limited Continuous Experimentation (dlCE) : a literature review

Continuous experimentation (CE) is a software development approach where product decisions are data-driven. Large global internet-facing companies such as Microsoft, Google, and Facebook apply the practice by leveraging their massive user bases to obtain high statistical significance in experimentation results. However, companies with smaller user bases, such as small- and medium-sized enterprises