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BACKGROUND: The tau-PET radiotracer [18F]flortaucipir enables in vivo detection of tau pathology in Alzheimer's Disease (AD) and has recently been FDA- and EMA-approved for clinical use. To support its implementation, we assessed tau-PET's positive predictive value (PPV) and negative predictive value (NPV) for clinico-pathological AD while accounting for age, amyloid-status, and pre-PET diagnostic
Background: Normal hand function relies on a finely tuned interaction between the sensory and motor systems within the central and peripheral nervous systems. The central nervous system continuously adapts to changed activity, environmental changes, learning, and injury — a phenomenon known as neuroplasticity. The neuroplasticity is a life-long ability and presents opportunities for therapeutic in
The T-REX neutron spectrometer at the European Spallation Source will use Multi-Grid Technology, which is a voxelised proportional counter relying on 10B4C coatings to detect neutrons scattered by the sample under investigation. Measurements of the position dependence of pulse-height and relative detection efficiency of a Multi-Grid prototype of the T-REX spectrometer are presented for two differe
Shared ground heat exchange can deliver low-carbon electrified heat where individual heat pumps or heat networks are not feasible, such as in terraced homes. However, there is a policy gap around these mid-scale heat solutions. We outline the benefits and challenges of shared ground heat exchange, and actions needed by policy, housing, and innovation stakeholders to support further deployment.
This paper examines income and employment outcomes for immigrants in Sweden’smost immigrant-dense neighbourhoods between 1998 and 2022. While relativeemployment among immigrants has improved, relative incomes in theseneighbourhoods have stagnated or declined. The most plausible explanation for thepersisting income gap and the shrinking employment gap between immigrant-dense and other neighbourhood
M i s t r a - s w e c i a | C l i m at e · I m pa c t s · a d a p tat i o n | w w w. m i s t r a - s w e c i a . s e Klimatanpassat skogsbruk: Drivkrafter, risker och möjligheter syntes- rapport 2 Mistra-Swecia 2015 Om rapporten...........................................................................................3 Mistra-SWECIA – forskning om klimat, effekter och anpassning.........5 Inlednin
https://www.hallbarhet.lu.se/sites/hallbarhet.lu.se/files/mistra-swecia_syntesrapport.pdf - 2026-07-02
The increase in the scale of LHC computing during Run 3 and Run 4 (HL-LHC) will certainly require radical changes to the computing models and the data processing of the LHC experiments. The working group established by WLCG and the HEP Software Foundation to investigate all aspects of the cost of computing and how to optimise them has continued producing results and improving our understanding of
Background: Up-to-date estimates of stroke burden and attributable risks and their trends at global, regional, and national levels are essential for evidence-based health care, prevention, and resource allocation planning. We aimed to provide such estimates for the period 1990–2021. Methods: We estimated incidence, prevalence, death, and disability-adjusted life-year (DALY) counts and age-standard
While pure deliberation has still not been found online, the field of online deliberation research is blossoming. Born out of the “frustrations and possibilities” of the 1990s, a current theme in the field is to re-link deliberative theory with empirical political science. The aim of this systematic literature review is to sort out and examine important features of this development; to identify an
Ultrasound optical tomography is a medical imaging modality that combines ultrasound and light to improve the low resolution of optical imaging caused by scattering in tissue. Photons passing through an ultrasound pulse have a probability of being frequency shifted. By filtering out these photons and analysing them, images with optical contrast and ultrasound resolution can be obtained. In this t
This thesis considers solitary standing wave solutions to the Davey-Stewart-son equation, which is a model for surface waves on a body of water in three dimensions. In a special case, the Davey-Stewartson equation is reduced to the well-known non-linear Schrödinger equation with cubic power which is known to have a countable familiy of radial standing waves. One of the aims of this thesis is to in
Purpose – The purpose of this study is to uncover what motivational factors exists for companies to use co-creational methods. It also aims to recognize what beneficial factors can come from using these methods. The restriction of using social media depending on industry or size of company will be reflected upon. The main research question is “What motivates companies to use customer co-creation a
Safety, privacy and comfort are elements that need to be improved on Swedish shelters. Since several homeless individuals often share bedrooms, it is not uncommon for them to be exposed to violence, harassment and theft or a generally disturbing environment during their stay. These are all contributing factors to an increased difficulty in getting out of homelessness. Enfold is a flexible w
The yield curve of a collection of debt contracts describes the yield of the debt contract as a function of the length-to-maturity of the contract. It turns out that these yield curves provide useful insight about the economy as a whole and can, for example, be used to predict short-term economic downturns. Therefore, it is of utmost importance that financial analysts and decision-makers are able
This environmental audit report was completed after an environmental audit of the Baltijsk municipality in the District of Kaliningrad, Russia, during the 10th and 11th of April 2000. The report is a joint effort of 31 students from 23 countries, who are participants of the International Master’s Programme “Master of Science in Environmental Management and Policy ” at the International Institute
The transition radiation tracker (TRT) is one of the three subsystems of the inner detector of the ATLAS experiment. It is designed to operate for 10 yr at the LHC, with integrated charges of /spl sim/10 C/cm of wire and radiation doses of about 10 Mrad and 2/spl times/10/sup 14/ neutrons/cm/sup 2/. These doses translate into unprecedented ionization currents and integrated charges for a large-sca
In the Full-Scale Optimization approach the complete empirical financial return probability distribution is considered; and the utility maximizing solution is found through numerical optimization. Using a portfolio choice setting of three UK equity indices we identify several utility functions featuring loss aversion and prospect theory; under which Full-Scale Optimization is a substantially bette
