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Ligands for the benzodiazepine-binding site of the GABAA receptor can belong to structurally diverse classes of compounds including, in spite of the name of the binding site, many non-benzodiazepine structures. The GABAA receptor is a ligand-gated ion channel assembled of five subunits from eight different classes with multiple isoforms. The physiological effect elicited by benzodiazepines is beli
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We find the Shannon limit to bit error rate (BER) as a function of E_b/N_0 for linear coded modulations. Error performance of TCM and other schemes can be compared to this curve. As the bandwidth of the signals in Hz-s/data bit drops, capacity becomes sensitive to the stopband spectrum, and the limit moves strongly away from the BER of practical systems when the stopband rolloff is not severe.
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In this paper, wave splitting technique is applied to a homogeneous Timoshenko beam. The purpose is to obtain a diagonal equation in terms of the split fields. These fields are calculated in the time domain from an appropriate set of boundary conditions. The fields along the beam are represented as a time convolution of Green functions with the excitation. The Green functions do not depend on the
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A relation between the radiation resistance and the quasi-static polarizability, input capacitance, and input inductance for small electric dipole antennas is investigated. The relation follows from the forward scattering sum rule and sum rules for the input impedance together with resonance models for the partial realized gain and the reflection coefficient.
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In a future fossil-free circular economy, the petroleum-based plastics industry must be converted to non-fossil feedstock. A known alternative is bio-based plastics, but a relatively unexplored option is deriving the key plastic building blocks, hydrogen and carbon, from electricity through electrolytic processes combined with carbon capture and utilization technology. In this paper the future dem
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Lipids have been implicated in beta-cell stimulus-secretion coupling. In such a role, lipases in beta-cells would be required to generate lipid coupling factors. We have shown previously that glucose stimulates lipolysis in rodent islets. In addition, lipolysis and diacylglycerol lipase activity in islets are abolished by orlistat, an irreversible lipase inhibitor with a broad specificity for subs
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A formula is proposed for the longshore sediment transport in the swash based on the study by Larson et al. on swash-zone transport and foreshore evolution. Hydrodynamics needed to predict the local transport rate were derived from ballistics theory, where both the cases with and without friction were investigated. The formula was validated with data from two experiments carried out in the Large-s
