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Background: Metabolic reprogramming, particularly glycolysis, is essential in processes like cancer and immune response. While FGF21's role in hepatocyte glucose metabolism has been linked to glucose transporters and its impact on aerobic glycolysis and cellular growth in HCC remain unclear. In this study, we investigated FGF21-mediated modulation of glucose metabolism in HCC through mTOR and HIF1

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This thesis is based on the work that was done during 1992--1996 at the DELPHI detector at LEP. Its main parts are outlined below. The brief Introduction gives an overview of the science of Particle Physics, its development and contemporary status. The first chapter represents an introduction to the DELPHI detector at LEP, describing the main features of the LEP machine and the DELPHI detector a

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Our aim was to describe patient flows in mandibular third molar surgery at ora I and maxillofacial specialist units. Our hypothesis was that there are variations in how care is delivered and that the variations could be explained by inter-individual variations in surgeons' practice,the quality of the radiographs appended to the referral, and the staffing of the specialist units. A flow chart was c

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Twenty-four children (aged 5 months to 18 years) who were admitted to a university hospital were observed for a total of 135 hours with the aim of describing their degree of participation in decisions concerning their own care. Grading of their participation was made by using a 5-point scale. An assessment was also made of what was considered as optimal participation in each situation. The results

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This study focus on the gelation process of 1-methylidene ethane-1,2-dicarboxylic acid (MIA) polyesters and what causes the gelation. The influence of oxygen during the syntheses, how the molecular weight is affected and how the polyester changes chemically was studied. Analytical methods used were SEC, titration and NMR. The replicability of the experiments was investigated and confirmed. Testing

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Mitochondrial quality control prevents accumulation of intramitochondrial-derived reactive oxygen species (mtROS), thereby protecting cells against DNA damage, genome instability, and programmed cell death. However, underlying mechanisms are incompletely understood, particularly in fungal species. Here, we show that Cryptococcus neoformans heat shock factor 3 (CnHsf3) exhibits an atypical function

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This study aims to contribute knowledge to the needs of managers in support of the return-to-work process of a burnt-out employee. This study explores managers’ perspectives on the organisational factors that they experience, how these factors affect them in the return to work process for a burnt out employee, and how these factors affect their feeling of being supported by their organisations and

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During the last decades, increased concentrations of natural organic matter (NOM) and colour of surface waters have been reported from northern Europe and North America. Since surface waters are widely used for drinking water production this development has been problematic for drinking water producers. Even though NOM in itself is not harmful, it can cause production of undesirable disinfection b

Qian Chen

Postdoc Kontaktinformation E-post: qian [dot] chen [at] fek [dot] lu [dot] seOrganisation Strategi Rumsnummer: Alfa 5,6 rum B426 Hämtställe: 10 WebbplatsQian Chens profil i Lunds universitets forskningsportalAndra roller Affilierad forskare CIRCLE Publikationer Visar av publikationer. Sorterade efter år och sen titel. Filtrera efter typ AllaArtikel i vetenskaplig tidskriftBokKonferenspaper i proce

https://www.ehl.lu.se/qian-chen - 2026-07-05