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Vacant commercial facilities are an increasing concern in many developed countries. Despitethe low occupancy rates in existing facilities, new commercial facilities that betteraccommodate the needs of modern end-users are constantly developed. In addition to financialconcerns, under-utilized spaces are a great environmental burden, as buildings account forapproximately one third of the global ener
The online-coupled 3-D chemistry transport model COSMO-MUSCAT was enhanced by a detailed description of aqueous phase chemical processes. The aqueous phase chemistry is represented by the detailed chemical mechanism CAPRAM 3.0i reduced (C3.0RED). In addition, the deposition schemes were improved in order to account for the deposition of matter incorporated in cloud droplets of ground layer clouds
This work proposes methodologies using a model-based approach to gain knowledge on and assist the development of an ion-exchange step in a protein purification process; the separation of IgG from a mixture containing IgG, insulin and transferrin. This approach is suitable for capture and intermediate steps in a process. Both methods involve four consecutive steps. Firstly, the retention of the dif
Background: Parkinson's disease (PD) is a progressive neurodegenerative condition that is expected to double in prevalence due to demographic shifts. Value-based healthcare is a proposed strategy to improve outcomes and decrease costs. To move towards an actual value-based health care system, condition-specific outcomes that are meaningful to patients are essential. Objective: Propose a global con
A method for synthesizing representative weather data for future climate out of regional climate models (RCMs) was introduced previously for the energy simulation of buildings (Nik, 2016). The method suggests creating one typical and two extreme data sets based on the distribution of the outdoor dry bulb temperature (Tdrybulb). This article extends the application of such weather data in the hygro
Previous studies on pessimism and optimism in organizations have mainly focused on productivity and performance. The aim of the current study was to investigate the role of optimism in the relationship between stress at work and health. An Internet-based questionnaire was sent to 1345 female and male employees at both managerial and non-managerial level working in a Swedish telecom company. Altoge
In the ActivAbles and STARR projects we have developed interactive training tools for stroke survivors. A prototype system includes an interactive balance foam pad, feedback lamps and a step counting game app which all connect to a central server. The feedback is designed to be inclusive - designs are multimodal, and the setup is flexible and can easily be adapted. We describe the system and repor
Non-healing wounds cause hundreds of thousands of deaths every year, and result in large costs for society. A key reason for this is the prevalence of challenging bacterial infections, which may dramatically hinder wound healing. With resistance development among bacteria against antibiotics, this situation has deteriorated during the last couple of decades, pointing to an urgent need for new woun
Background: The causes of obsessive-compulsive disorder (OCD) remain unknown. Gene-searching efforts are well underway, but the identification of environmental risk factors is at least as important and should be a priority because some of them may be amenable to prevention or early intervention strategies. Genetically informative studies, particularly those employing the discordant monozygotic (MZ
Residential energy-related renovations have a high potential to reduce emissions. However, organizing such renovation is riddled with high transaction costs. In response, scholars and policymakers (e.g., European Commission) have advocated the One-Stop-Shop (OSS) concept to simplify house owners' access to complex renovation solution, but adoption of the concept remains slow. So far, research has
The mechanisms responsible for macrovascular complications in diabetes remain to be fully understood. Recent studies have identified impaired vascular repair as a possible cause of plaque vulnerability in diabetes. This notion is supported by observations of a reduced content of fibrous proteins and smooth muscle cell mitogens in carotid endarterectomy from diabetic patients along with findings of
Background: Acute aortic syndrome (AAS) is a life-threatening condition reported as often misdiagnosed. Advancements in CT availability and diagnostic algorithms, including high-sensitivity troponin and D-dimer for acute coronary syndrome (ACS) and pulmonary embolism (PE), may reduce AAS misdiagnosis, but the impact remains unclear. This study evaluated the incidence, characteristics, and clinical
One of the most interesting features of nuclei is the process by which specific configurations, manifest as collective rotational bands at intermediate spin values, gradually lose their collectivity and terminate in a non-collective state at the maximum spin which can be built within the configuration. Recent advances in both experiment and theory allow the study of this nuclear structure feature
