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Välkommen till Institutionen för hälsovetenskaper, en av sex institutioner vid Medicinska fakulteten, Lunds universitet. Genom vår forskning ökar vi kunskapen och förståelsen om människors hälsa och livskvalitet. Hälsofrämjande och förebyggande insatser, behandlande åtgärder, vård och omsorg och rehabilitering är centrala forskningsområden. Vi arbetar i nära samarbete med hälso- och sjukvård och kThe Department of Health Sciences is one of six departments at the Faculty of Medicine, Lund University. We conduct research within the field of health sciences. Health promotion and prevention efforts, Treatment measures, Health and social care and Rehabilitation are key research areas. We work in close collaboration with health care and municipalities to translate research results into practical

Hjärt-kärlsjukdom är världens vanligaste dödsorsak. Det främsta underliggande tillståndet är ateroskleros: plack som bildas i blodkärlens väggar och kan orsaka akuta komplikationer, såsom hjärtinfarkt och stroke. Genom vår forskning ämnar vi identifiera kliniska metoder som kan hjälpa oss att hitta plack med hög komplikationsrisk, för att i tid kunna ge adekvat förebyggande behandling. Vi vill äveCardiovascular disease is the most common cause of death. The main underlying condition is atherosclerosis: plaques formed in the arteries which can cause complications as stroke or myocardial infarction. Our research aims to prevent complications by identifying clinical methods to detect patients with high-risk plaques to personalize treatment strategies as well as novel mechanisms to use as ther

Existing metastatic disease represents a major clinical challenge. The long-term goal of our study is to gain deeper understanding of cellular mechanisms underlying cancer metastasis. We focus on identification and validation of new predictive biomarkers and drug targets that are specifically for metastatic cancer. We recently focus on studying the role of lipid kinases in particular, phosphatidyl

MicroRNAs have emerged as regulators of smooth muscle cell phenotype with a role in smooth muscle-related disease. Studies have shown that miR-143 and miR-145 are the most highly expressed microRNAs in smooth muscle cells, controlling differentiation and function. The effect of miR-143/145 knockout has been established in the vasculature but not in smooth muscle from other organs. Using knockout m

SDE at Lund University conducts research on the development of new tools, languages, and methods for software development. Example areas include compilers, program analysis, domain-specific languages and tools, meta-programming tools, integrated development environments, code review tools, adaptive developer tools, agile methodology, software architecture and design, pervasive systems, internet-of

Sortilin, a member of the Vps10p-domain receptor family, has been demonstrated a key regulator in mediating cellular response to pro-neurotrophins. In the present study, we investigated the role of sortilin in the apoptotic pathway of vascular smooth muscle cells.

Aim: This paper describes the quality assurance (QA) work performed in the Swedish multicenter ARTSCAN (Accelerated RadioTherapy of Squamous cell CArcinomas in the head and Neck) trial to guarantee high quality in a multicenter study which involved modern radiotherapy such as 3DCRT or IMRT. Materials and methods: The study was closed in June 2006 with 750 randomised patients. Radiation therapy-rel

Education for sustainability (EfS) has been regarded a promising approach for solving sustainability challenges. Results have been unsatisfying due to a knowledge-dissemination focus in the formal sector. Reasons are economic and political interests shaping formal education. Therefore, hopes are placed in the non-formal sector to close this knowledge-to-action gap. In this case study, I aim to und

The combustion process in a hydrogen fueled scramjet combustor with a rearwall-expansion cavity was investigated numerically under inflow conditions of Ma=2.52 with stagnation pressure P0=1.6 Mpa and stagnation temperature T0=1486 K. The numerical solver was first evaluated for supersonic reactive flows in a similar combustor configuration where experimental data is available. Wall-pressure distri

How can openness, intuition and external creative tools be valuable assets to the creative process? In this thesis, I explore that question as it relates to three distinct perspectives: my reflections on my own approach, other artists’ thoughts on the subject and the composition of my orchestral piece "let me cry" (2022). My findings are that by integrating openness, intuition, and exte

Purpose: The academic aim is to test the Entrepreneurial Architecture framework by Nelles and Vorley (2010a) against a department in relation to the creation of spin-offs. This is something we believe has not been done before and can add to the literature about departments in this respect. The practical objective is to present useful insights that help practitioners manage the complexity of this t

Since 1978, Reform and Opening Up, China has acquired relatively remarkable achievements in urbanization, especially in coastal provinces like Guangdong Province. Under the special contexts of China after 1978, while Guangdong Province has been achieving more and further in the urbanization process, the rural-urban disparities has also been enlarging in many aspects. This empirical study shows and

BACKGROUND: Individuals with mental health problems often need support from vocational rehabilitation professionals in their return-To-work (RTW) process. Research has shown that this support can be deficient, with vocational rehabilitation professionals lacking relevant knowledge and an underlying belief in the individual's ability to resume a working life. More understanding is therefore needed

Methodological considerations in practice-based research: lessons learned from research with a music school in SwedenThis is a presentation of a practice-based research project that has been carried out in collaboration between two course leaders from a music school in Sweden and one researcher between 2022 and 2023. The aim of the research project is to contribute to knowledge about pupil partici

This thesis investigates the Japanese music industry from a liberal feminist perspective, as academic literature rarely discusses Japanese music – especially niche genres like metal. After pinpointing a gap in the literature on the subject, and after outlining issues in the Japanese music industry, this study sheds light on the reasons that lead Japanese women musicians to thrive outside of major

Mitochondrial fusion and fission are dynamic processes regulated by the cellular microenvironment. Under nutrient starvation conditions, mitochondrial fusion is strengthened for energy conservation. We have previously shown that newborns of Ubl4A-deficient mice were more sensitive to starvation stress with a higher rate of mortality than their wild-type littermates. Ubl4A binds with the actin-rela