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Background Gastrointestinal symptoms and changes in colonic transit time (CTT) are common in the population. Purpose To evaluate consecutive patients who had been examined for CTT, along with completion of a diary about laxative and drug use, lifestyle factors, and gastrointestinal symptoms, to identify possible associations with longer or prolonged CTT. Material and Methods A total of 610 consecu
Objectives: The clinical significance of low-level viraemia (LLV) during antiretroviral therapy (ART) is debated. We retrospectively investigated longitudinal levels of plasma markers associated with inflammation, altered coagulation and cardiovascular disease in Swedish HIV-positive adults in relation to LLV or permanent virological suppression during long-term ART. Methods: Plasma levels of C-re
ST segment depression (STDE) has been found to be associated with cardiovascular disease in the elderly. Studies of the relation of ambulatory STDE to cognitive function in elderly persons aged 80 years or above is lacking. Objective: To study the association between STDE and cognition. Design and participants: A cross-sectional cohort study of 88 81-year-old men from the population study "Men bor
This essay attempts to explore what being fat means in relation to health and illness for overweight and non-overweight children aged 8-12 years. It illustrates that overweight children experience being fat as a social problem and not merely as a medical or Health problem. Their concept of overweight is influenced by the beliefs that are present in the World around them and the problems they face
Fossil fuel companies’ existence is incompatible with the planet’s survival, says Bill McKibben Paris 2015 will be one step along the line, not the thing that solves all the problemsWe now have solutions we didn’t have 25 years ago, we should deploy them with all possible speed
Doktorand Kontaktinformation E-post: heraclitos [dot] muhire [at] soclaw [dot] lu [dot] seOrganisation Rättssociologiska institutionen Hämtställe: 31 WebbplatsHeraclitos Muhires profil i Lunds universitets forskningsportalAndra roller Forskningsassistent Rättssociologiska institutionenForskningsområdenSvängdörrar mellan offentlig sektor och näringslivArbetskraftsexploatering av migrantarbetareAcce
https://www.soclaw.lu.se/heraclitos-muhire - 2026-06-30
To identify stop-codon variants associated with blood pressure (BP).
BACKGROUND AND PURPOSE: Extracellular adenosine triphosphate (ATP) regulates inflammatory cells by activation of the P2X(7) receptor. We hypothesized that polymorphisms in P2RX7 influence the risk of ischemic heart disease (IHD), ischemic stroke (IS) and cardiovascular risk factors and tested this hypothesis using genetic association studies. METHODS: Two loss-of-function SNPs in P2RX7 were genot
Single-strand RNA-binding proteins (RBPs) are involved in many aspects of RNA metabolism and in the regulation of gene transcription. The RBP RBM3 was recently suggested to be a proto-oncogene in colorectal cancer; however, such a role has not been corroborated by previous studies in the colon or other tumor types, and the prognostic implications of tumor-specific RBM3 expression remain unclear. M
Idiopathic pulmonary fibrosis (IPF), an insidious disease with grave prognosis, is characterized by heterogeneous fibrosis with densely fibrotic areas surrounded by nonfibrotic normal-looking tissue, believed to reflect a temporal development. The etiology is incompletely elucidated, but aberrant wound healing is believed to be involved. Embryonic signaling pathways, including Wnt signaling, are r
BACKGROUND: It has been suggested that osteoblasts are involved in the regulation of haematopoietic stem cells. Whether osteocalcin, which is derived from osteoblasts and is metabolically active, influences blood haemoglobin (Hb) levels is not known.OBJECTIVE: To determine whether plasma osteocalcin is a determinant of Hb in elderly men.METHODS: A total of 993 men (mean age 75.3 ± 3.2 years) parti
Breast cancer is the most common cancer form among women today. Depending on hormone receptor status, breast cancers are divided into different subtypes with vastly varying prognosis. S100A9 is a calcium-binding protein that is associated with inflammation and expressed not only in myeloid cells but also in some tumours. The role for S100A9 in the malignant cells is not well characterised; however
We have previously shown that genetic variance in NEDD4L, a regulating protein of a sodium channel in the distal nephron, has been associated with marginally higher blood pressure and enhanced salt sensitivity. Here, we tested if the genetic NEDD4L variation previously associated with salt sensitivity is related to population blood pressure, incidence of cardiovascular disease (CVD) and mortality.
NYTT FRÅN LUNDS UNIVERSITET Mejlutskick på svenska och engelska som vänder sig till fakultetskommunikatörer vid Lunds universitet för vidarespridning i fakultets- och institutionskanaler – Nr 19 v 21 - 2021. CORONARELATERAT Rekommendationen om distansutbildning som utgångsläge tas bort Den 27 maj presenterade regeringen sin plan i fem steg för anpassning och avveckling av de restriktioner som tagi
https://www.cec.lu.se/sites/cec.lu.se/files/2021-06/LU-gemensamt%20Mejlutskick%20Nr%2019-v21-2021.pdf - 2026-07-01
It has been demonstrated that tissue factor (TF) may be involved in the tumor-derived procoagulatory status and angiogenic modulation in certain solid tumors. In the present study, we examined immunohistochemical localisation of TF in esophageal squamous cell carcinomas (ESCC) from 103 patients. TF immunopositivity was found in 91.3% of all tumor sections, while normal esophageal tissues were immu
Objective: To test the hypothesis that the growth hormone (GH) receptor (GHR) d3/fl polymorphism influences anthropometry and body composition in the general population. Design and Setting: The Swedish Obese Subjects (SOS) reference study is a cross-sectional population-based study, randomly selected from a population registry. A sub-group of the population-based Malmö Diet and Cancer Study (MDC-C
Staphylococcus aureus is sometimes isolated from the airways during acute exacerbations of chronic obstructive pulmonary disease (COPD) but more commonly recognized as a cause of ventilator-associated pneumonia (VAP). Antimicrobial proteins, among them midkine (MK), are an important part of innate immunity in the airways. In this study, the levels and possible processing of MK in relation to S. au
Adiponectin enhances insulin sensitivity and may play a role in fetal and postnatal growth.
Introduction: Polymorphonuclear leukocytes (PMN) are main effector cells in the acute immune response. While the specific role of PMN in systemic lupus erythematosus (SLE) and autoimmunity is still unclear, their importance in chronic inflammation is gaining more attention. Here we investigate aspects of function, bone marrow release and activation of PMN in patients with SLE. Methods: The followi
