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Antibody radionuclide conjugates are an emerging modality for targeted imaging and potent therapy of disseminated disease. Coupling of radionuclides to monoclonal antibodies (mAbs) is typically achieved by applying non-site-specific labelling techniques. With the ambition of reducing variability, increasing labelling efficacy and stability, several site-specific conjugation strategies have been de

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Objective: To validate a prediction model for successful vaginal birth after Cesarean delivery (VBAC) based on sonographic assessment of the hysterotomy scar, in a Swedish population. Methods: Data were collected from a prospective cohort study. We recruited non-pregnant women aged 18–35 years who had undergone one previous low-transverse Cesarean delivery at ≥ 37 gestational weeks and had had no

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Background: Earlier attempts to deliver effective lung doses of surfactant by aerosolization were unsuccessful, mostly because of technical shortcomings. We aimed at quantifying the lung deposition of poractant alfa with a new supraglottic delivery system for surfactant atomization in an experimental neonatal model. Methods: The method involved six sedated 1-day-old piglets lying in the lateral de

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Growth factors promote plasticity in injured brain and improve impaired functions. For clinical application, efficient approaches for growth factor delivery into the brain are necessary. Poly(ester amide) (PEA)-derived microspheres (MS) could serve as vehicles due to their thermal and mechanical properties, biocompatibility and biodegradability. Vascular endothelial growth factor (VEGF) exerts bot

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This study evaluated the safety and tolerability of ocular RS1 adeno-associated virus (AAV8-RS1) gene augmentation therapy to the retina of participants with X-linked retinoschisis (XLRS). XLRS is a monogenic trait affecting only males, caused by mutations in the RS1 gene. Retinoschisin protein is secreted principally in the outer retina, and its absence results in retinal cavities, synaptic dysfu

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Encapsulation systems have long been studied, and the designs have varied in both capsule material as well as the type of cargo. The intended use have ranged from nanoreactors to delivery systems. This work presents an encapsulation system consisting of protein capsule and a protein cargo. The capsule is a redesigned hepatitis B virus capsid protein, in which the luminal extension has been altered

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Linde Gas is one division belonging to The Linde Group, which is an industrial gas and engineering company. With its 53000 employees in 70 countries and related sales of about €12 billion, The Linde Group is a world leading company. Linde Gas has two different types of delivery agreements which are seen as profitable; the customer can call in himself to place an order (”Order Only” customer) or th

Verksamhetsberättelse 2020 För EBSCO Systems Nordic User Group

Verksamhetsberättelse 2020 för EBSCO Systems Nordic User Group Verksamhetsåret 2020 präglades i stort av en global coronaviruspandemi med anledningen av spridningen av SARS-CoV-2 (se mer här: https://sv.wikipedia.org/wiki/Coronaviruspandemin_2019%E2%80%932021). Pandemin innebar för verksamheten att inga fysiska träffar kunde hållas under året. Därför anordnade föreningen endast digitala möten och

https://www.ub.lu.se/sites/ub.lu.se/files/2021-04/Verksamhetsber%C3%A4ttelse%202020%20f%C3%B6r%20EBSCO%20Systems%20Nordic%20User%20Group.pdf - 2026-06-30

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The aim of this study was to develop a novel software platform for the simulation of magnetic resonance spin systems, capable of simulating a large number of spatial points (1283 ) for large in vivo spin systems (up to seven coupled spins) in a time frame of the order of a few minutes. The quantum mechanical density-matrix formalism is applied, a coherence pathway filter is utilized for handling u

Schema mvec12 180629

MILJÖVETENSKAP PRELIMINÄRT SCHEMA 2018-06-29 (med reservation för ändringar) Kurs: Riskanalys inom natur, miljö- och hälsa MVEC12, HT 2018, 15 HP Kursansvarig: MARIA HANSSON Maria.Hansson@cec.lu.se; 046-2224628 Lärare: Thomas Lund (TL) Arbets- och miljömedicin, Christian Lindh (CL) Arbets- och miljömedicin, Margareta Littorin (ML) Arbets- och miljömedicin, Estelle Larsson (EL) Arbets- och miljömed

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/schema_mvec12_180629.pdf - 2026-06-30

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In this study, a rapid and sensitive ultra-high performance supercritical fluid chromatography-mass spectrometry (UHPSFC-MS) method has been developed and partially validated for the separation of carotenoids within less than 6 min. Six columns of orthogonal selectivity were examined, and the best separation was obtained by using a 1-aminoanthracene (1-AA) column. The length of polyene chain as we

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This chapter will analyse the Trade secret Directive from a technological informed legal perspective, looking at the possibilities and scope of protection that it offers for knowledge based activities and business models. It opens by restating the basic yet important fact that “Information is power”. Asymmetries in information are a fundamental transaction cost and in this sense informational qual