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Development and validation of a novel Simoa assay for NPTX2 in Alzheimer's disease and Down syndrome

INTRODUCTION: Synaptic dysfunction and loss are pathological hallmarks of neurodegenerative diseases. Neuronal pentraxin 2 (NPTX2), a presynaptic protein involved in synaptic plasticity, has been linked to cognitive decline in Alzheimer's disease (AD) and other neurodegenerative disorders. METHODS: We developed and validated a novel single molecule array (Simoa) for NPTX2 in cerebrospinal fluid, w

Results of a phase I/II study of ocrelizumab, a fully humanized anti-CD20 mAb, in patients with relapsed/refractory follicular lymphoma

Background: Ocrelizumab is a humanized anti-CD20 antibody with increased antibody-dependent cellular cytotoxicity compared with rituximab. This phase I/II study evaluated its safety and efficacy in patients with relapsed/refractory follicular lymphoma (FL) after prior rituximab therapy. Design and methods: Forty-seven patients were treated in three dose cohorts and received eight infusions every 3

Streptococcus pyogenes secreted enzymes interacting with the human host

Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. SpeB activity depends on the transformation from an inactive precursor, zymogen, into a mature proteinase. We show that

Energy Storage & Conversion

Sustainable energy storage and conversion explores innovative methods to efficiently store and transform energy from various renewable sources. It focuses on technologies like advanced batteries, hydrogen production, fuel cells, and thermochemical systems as well as safety aspects of battery storage systems. Research aims to enhance energy density, reduce costs, and improve scalability, enabling r

https://www.energy.lth.se/research/energy-storage-conversion - 2026-05-21

Ownership - a challenged Consumer Ideal. A Study of two Collaborative Consumption Practices: Clothes Swapping and Clothing Libraries

This research is a theoretical contribution to CCT and existing literature on ownership, investigating whether ownership has become an out-dated ideal in consumer culture. We explore how Millennials negotiate issues of ownership and sharing in the context of collaborative consumption. Consequently, the study provides insights on new consumption forms, and more specifically swapping and access-base

FlexPES : a versatile soft X-ray beamline at MAX IV Laboratory

FlexPES is a soft X-ray beamline on the 1.5 GeV storage ring at MAX IV Laboratory, Sweden, providing horizontally polarized radiation in the 40-1500 eV photon energy range and specializing in high-resolution photoelectron spectroscopy, fast X-ray absorption spectroscopy and electron-ion/ion-ion coincidence techniques. The beamline is split into two branches currently serving three endstations, wit

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Untitled Master’s Dissertation Structural Mechanics JUAN CARDENAL BASTÉ Report TV SM -5150 JU A N C A RD EN A L BA STÉ D ESIG N M ETH O D FO R STR U T-B EA M C O N N EC TIO N IN H IN G ED FR A M ES DESIGN METHOD FOR STRUT-BEAM CONNECTION IN HINGED FRAMES Detta är en tom sida! Copyright © 2012 by Structural Mechanics, LTH, Sweden. Printed by Media-Tryck LU, Lund, Sweden, July, 2012 (Pl). For inform

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm5000/web5150.pdf - 2026-05-21

Policy om anställning och goda och tydliga karriärvägar för lärare och forskare vid Lunds universite

Microsoft Word - Anställningspolicy_beslutad US18juni2019§6b 1   POLICY OM ANSTÄLLNING OCH GODA OCH TYDLIGA KARRIÄRVÄGAR FÖR LÄRARE OCH FORSKARE VID LUNDS UNIVERSITET Fastställd av universitetsstyrelsen 2019-06-18, §6b Inledning och syfte Lunds universitet är ett fullskaligt, forskningsintensivt, mångfacetterat och decentraliserat universitet. Att främja goda och tydliga karriärvägar i alla delar

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/policy-om-anstallning-och-goda-och-tydliga-karriarvagar-for-larare-och-forskare-vid-lu-190618.pdf - 2026-05-22

State of fairness in esfri projects

Since 2009 initiatives that were selected for the roadmap of the European Strategy Forum on Research Infrastructures started working to build research infrastructures for a wide range of research disciplines. An important result of the strategic discussions was that distributed infrastructure scenarios were now seen as “complex research facilities” in addition to, for example traditional centralis

Treatment of Textile Wastewater by Combining Biological Processes and Advanced Oxidation

Popular Abstract in English Colors have always been part of human life and culture. Today natural pigments have been substituted by synthetic dyes that usually end up threatening nature itself by polluting the environment. To what extent can we use chemistry and biology to minimize the environmental impact of the textile industry? During the dyeing process a certain amount of dye, 2 to 50 percent,Treatment of textile wastewater is challenging because the water contains toxic compounds that have low biodegradability. Dyes, detergents, surfactants, biocides and more are used to improve the textile process and to make the clothes resistant to physical, chemical and biological agents. New technologies have been developed in the last decades and in particular Advanced Oxidation Processes (AOPs)

Report on improved use of individual metering concept

In a low temperature district heating (LTDH) system the importance of well performing network and customer installations are essential due to reduced operation margins. The use of low-value waste heat in the production sets limitations on the supply temperature. New piping materials sets limitations on the supply temperature and the pressure level. All in all, this means an increased focus on ensu