Filtyp
Transboundary environmental problems pose a specific challenge to the international legal system, as they often demand instruments providing for collective and far-reaching measures on a global scale. Such measures may interfere with other areas of international law, including trade law, human rights law and international humanitarian law (IHL), which may permit conflicting behaviour. The interfer
The purpose of this thesis is to analyze how the two Swedish reforms, child-care allowance and earned income tax credit (EITC) will affect the labour supply. The child-care allowance will be introduced in Sweden during 2008. The aim is to increase the freedom of choice for parents regarding their child-care. In order to be eligible to the allowance, the children need to be between the ages of one
Increased shale gas extraction through hydraulic fracturing and its distribution through shale gas pipelines have brought about innumerable socioeconomic consequences, both tangibly and intangibly. Evidence remains unclear on what are the impacts of shale gas developments on property values. By employing a mixed method approach, combining original data collected in the Marcellus Shale through inte
This chapter presents three interviews with three influential voices in the field of social movement and civil society studies, namely, those of Doug McAdam, Jeffrey Alexander, and Nina Eliasoph. They all share their perspectives on social movements’ role in society’s moral development, the role of morality internally in social movements, and the role of morality for social science as a practice.
Bread is the main food source that cuts horizontally across historical, social, cultural and economic areas. Bread is produced and consumed in the context of economic, political and social relations throughout human history. The factors affecting the production of bread are discussed. The political economy of the public bread practice, which is produced and distributed by the municipalities, is st
Cell fate reprogramming of adult cells towards pluripotency or unrelated somatic cell-types has been explored in the context of regenerative medicine. Dendritic cells (DCs) are professional antigen presenting cells (APCs) specialized in the recognition, processing and presentation of antigens to T-cells, inducing adaptive immunity. In particular, the mouse conventional DCs type 1 (cDC1) subset or
Background: Contrary to the presumption that type 1 diabetes leads to an absolute insulin deficiency, many individuals with type 1 diabetes have circulating C-peptide years after the diagnosis. We studied factors affecting random serum C-peptide concentration in individuals with type 1 diabetes and the association with diabetic complications. Methods: Our longitudinal analysis included individuals
Today, many control applications in cyber-physical systems are implemented on shared platforms. Such resource sharing may lead to complex timing behaviors and, in turn, instability of control applications. This paper highlights a number of anomalies demonstrating complex timing behaviors caused as a result of resource sharing. Such anomalous scenarios, then, lead to a dramatic increase in design c
Spina bifida (SB) is a debilitating birth defect caused by multiple gene and environment interactions. Though SB shows non-Mendelian inheritance, genetic factors contribute to an estimated 70% of cases. Nevertheless, identifying human mutations conferring SB risk is challenging due to its relative rarity, genetic heterogeneity, incomplete penetrance, and environmental influences that hamper genome
Neutrophils are commonly regarded as the first line of immune response during infection or in tissue injury-induced inflammation. The rapid influx of these cells results in the release of host defense proteins (HDPs) or formation of neutrophil extracellular traps (NETs). As a second wave during inflammation or infection, circulating monocytes arrive at the site. Earlier studies showed that HDPs LL
We model the effects of collisions and close encounters on the stellar populations observed in the Milky Way nuclearstellar cluster (NSC). Our analysis is based on N -body simulations in which the NSC forms by accretion of massivestellar clusters around a supermassive black hole. We attach stellar populations to our N -body particles and follow theevolution of their stars, and the rate of collisio
Sepsis manifests due to the host's dysregulated immune response to infection. High-dose ascorbic acid (AA) has emerged as a potential treatment of sepsis, yet little is known regarding how AA influences the immune system in sepsis, such as monocytes. The objective of this study is to investigate the effects of high-dose AA on monocyte polarization and cytokine production in vitro. Monocytes isolat
Otitis media (OM) is an inflammatory disorder in the middle ear. It is mainly caused by viruses or bacteria associated with the airways. Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis are the three main pathogens in infection-related OM, especially in younger children. In this review, we will focus upon the multifaceted gene regulation mechanisms that are well-orchestra
Cutibacterium acnes (C. acnes) is a gram-positive bacterium and a member of the human skin microbiome. Despite being the most abundant skin commensal, certain members have been associated with common inflammatory disorders such as acne vulgaris. The availability of the complete genome sequences from various C. acnes clades have enabled the identification of putative methyltransferases, some of the
This study proposes a novel design of binders for polycrystalline cubic boron nitride (PcBN) cutting tool materials. Well-known binder phases TiC and TiN were combined with transitional metal nitrides ZrN, VN, and HfN. Performance screenings of longitudinal turning Inconel 718 and AISI 316 L highlighted the superior performance of PcBN materials with mixed TiC-ZrN and TiC-VN binders. These two sys
The structural set-up and key characteristics of regulatory regimes for risk management vary between countries, technical domains and application areas. Risk regulations come in different forms, ranging from a highly prescriptive (“hard”) approaches including explicit requirements on key risk management components, to “softer” approaches requiring risk to be managed without defining how. Risk regu
OBJECTIVE: The aim of the study was to investigate the associations of total sleep time (TST) and occupational stress based on the Brief Job Stress Questionnaire (BJSQ) with cholesterol levels in an occupational cohort of Japanese office workers. METHODS: The present study is a secondary analysis of a subset of participants from a randomized controlled trial. Participants were 179 employees from 5
Introduction and Objectives: To compare pilot cohorts of men scheduled for radical prostatectomy imaged with novel antibody conjugates: Cohort 1 (111In-J591) single photon emission tomography (SPECT) or Cohort 2 (89Zr-J591) positron emission tomorgraphy (PET).Methods: 1) Cohort 1: Eight patients with abnormal digital rectal exam and biopsy proven prostate cancer were injected intravenously with tw
Timber buildings are intrinsically lightweight and hence can be susceptible to low-frequency vibrations and structure-borne noise. So, within the development of technical solutions for mitigating unwanted vibrations and noise, accurate and computationally efficient numerical models are considered to be of great value. Such models should take into account all physical phenomena that are relevant fo
