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Increased age, BMI and HbA1c levels are risk factors for several non-communicable diseases. However, the impact of these factors on the genome-wide DNA methylation pattern in human adipose tissue remains unknown. We analyzed DNA methylation of ∼480,000 sites in human adipose tissue from 96 males and 94 females, and related methylation to age, BMI and HbA1c. We also compared epigenetic signatures i
Background: Most validations of paediatric glomerular filtration rate (GFR) estimating equations using standardized creatinine (CR) and cystatin C (CYS) assays have comprised relatively small cohorts, which makes accuracy across subgroups of GFR, age, body mass index (BMI) and gender uncertain. To overcome this, a large cohort of children referred for GFR determination has been established from se
The aim of this study was to investigate the effect of training on the in vivo tibial structural strength during the development of post-ovariectomy osteoporosis. Seventeen mature Wistar rats (215 g) were ovariectomized and randomized into two groups. The sedentary control group was kept cage confined, while 3 days postoperatively the trained group started treadmill running with high intensity for
A recent study carried out by our group demonstrated that exogenous dopamine increases the somatostatin (SS) receptor–effector system in the rat striatum. The present study examined the participation of the D1- and D2-dopaminergic systems in the modulation of the rat striatal SS receptor–effector system by use of the D1-receptor agonist and antagonist SKF 38393 and SCH 23390, respectively, and the
Qusta ibn Luqa (fl. 860) was a prominent figure in the Graeco-Arabic translation movement that reached its peak in the 9th century. At the request of wealthy and influential commissioners, Qusta translated Greek works on astronomy, mathematics, mechanics and natural science into Arabic. He also produced works of his own: more than sixty treatises are attributed to him. He wrote mainly on medical s
Ovariectomized virginal rabbits were treated with either estrogen or progesterone for 4 to 6 months. In vitro responses of muscle strips of the bladder and circular urethra were examined. Estrogen resulted in bladder contractions in response to noradrenaline and phenylephrine, whereas these agonists were without effect or evoked weak relaxations in castrated animals (and normals). Estrogen also ca
We have measured the uptake capacity of nitrogen (N) and potassium (K) from different soil depths by injecting N-15 and caesium (Cs; as an analogue to K) at 5 and 50 cm soil depth and analysing the recovery of these markers in foliage and buds. The study was performed in monocultures of 40-year-old pedunculate oak (Quercus robur), European beech (Fagus sylvatica) and Norway spruce (Picea abies (L.
The Knee injury and Osteoarthritis Outcome Score (KOOS) is a self-administered instrument measuring outcome after knee injury at impairment, disability, and handicap level in five subscales. Reliability, validity, and responsiveness of a Swedish version was assessed in 142 patients who underwent arthroscopy because of injury to the menisci, anterior cruciate ligament, or cartilage of the knee. The
I samtida digital kultur har sociala medieplattformar blivit centrala arenor för förhandlingar kring kön, intimitet och attraktion. Tidigare forskning har i hög grad fokuserat på hur kvinnor representeras och objektifieras online, medan mindre uppmärksamhet har ägnats åt hur kvinnor kollektivt tolkar, kategoriserar och värderar män i digitala miljöer. Denna studie adresserar denna forskningslucka
Lakes with increased water colour levels have been observed in many locations in the northern hemisphere, a phenomenon that is called brownification. The driving components of brownification are dissolved organic matter (DOM) and iron, which are affected by rainfall patterns as a large fraction originates from terrestrial sources. Brownification has many detrimental effects for the ecosystem, amon
1 BLÅGRÖNA LÖSNINGAR I SOFIELUND - Klimatanpassningsåtgärder i allt tätare städer JOHANNA ALKAN OLSSON OCH HELENA HANSON 2 Blågröna lösningar i Sofielund - klimatanpassningsåtgärder i allt tätare städer Johanna Alkan Olssson och Helena Hanson Centrum för miljö och klimatforskning, Lunds universitet, 2018 Johanna.alkan_olsson@cec.lu.se Helena.hanson@cec.lu.se 3 INNEHÅLL 1. INLEDNING 2. PRINCIPLÖSNI
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/blagrona_losningar_sofielund.pdf - 2026-07-20
Sensitivity, specificity, and agreement between clinical and magnetic resonance imaging (MRI) gradings of the medial collateral ligament (MCL) after acute knee injury were evaluated in 362 patients. Ninety-seven per cent were injured during sports/recreation. Sensitivity and specificity of MRI for grade II or III MCL injury was 68% (95% CI 58–77%) and 90% (95% CI 86–93%), respectively. Weighted Ka
Aim: This thesis aims to develop a deeper understanding of how junior and senior preschool teachers engage in knowledge sharing and learning in a public sector organisation as well as how their knowledge sharing and learning behaviour is being challenged. Literature Review: Our literature review focuses on knowledge and knowledge sharing and relates it specifically to the public sector which corre
Contract law has traditionally been regulated by national law which has raised certain problems in cross-border transactions caused by the divergences in domestic contract law among the Member States. Therefore, the diversity of national law has been increasing the challenges in practice for entrepreneurs which is causing a lack of legal certainty, uniformity and creates serious obstacles that hin
Finansmarknaden genomgick stora förändringar innan 2000-talet och placeringsrådgivning kom att spela en allt viktigare roll. Tidigare hade det inte funnits lagstiftning på området, vilket man nu införde. Först kom Lag (2003:862) om finansiell rådgivning till konsumenter (FRL), därefter utfärdades ett EG-direktiv. Direktivet införlivades i svensk rätt genom Lag (2007:528) om värdepappersmarknaden (The Financial Market went through significant changes before the 2000’s and investments advisory played an increasingly important role. Earlier there had not been any legislation on the subject which there is now. The first legislation was the act of financial advisory and after that the Markets in Financial Instruments Directive, MiFID came from the EU. MiFID was implemented into Swedish law thro
We are at what appears to be an impasse. Almost everyone across the world – and certainly in the west – has heard of climate change and knows at least a bit about what it means. Yet dominant norms, values and behaviours in the human-ecological relationship still persist, despite the fact that many of these are agreed to be the very source of the problem. Finding a way – or more accurately, ways –
Background: Fruit and vegetable consumption might prevent weight gain through their low energy density and high dietary fiber content. Objective: We assessed the association between the baseline consumption of fruit and vegetables and weight change in participants from 10 European countries participating in the European Prospective Investigation into Cancer and Nutrition study. Design: Diet was as
Life oil earth was formed during billions of years, exposed to, and shaped by the original physical forces such as gravitation, cosmic irradiation, atmospheric electric fields and the terrestrial magnetism. The Schumann resonances at 7.4 Hz are all example of oscillations possibly important for life.(1)) The existing organisms are created to function in harmony with these forces. However, in the l
