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The beam-foil excitation technique has been applied to determine lifetimes of the 3p2P1/2, 2P3/2 and 3d2D3/2, 2D5/2 levels in Na-like Cl VII. Using the ANDC method accurate values have been obtained which confirm recent theoretical values and explain some previously noted differences between theoretical and experimental oscillator strengths for transitions in multiply ionized Na-like ions.
Pulmonary arterial hypertension (PAH) is a condition that leads to lethal right heart failure. Available treatments provide relief but are far from curative and the vascular remodeling in PAH has been difficult to decipher. Although pathognomonic to PAH, the plexiform lesions are difficult to define, and there is no consensus regarding their potential hemodynamic impact. Versican is an extracellul
Therapeutic resistance is one of the main reasons for treatment failure in cancer patients. The polyaneuploid cancer cell (PACC) state has been shown to promote resistance by providing a refuge for cancer cells from the effects of therapy and by helping them adapt to a variety of environmental stressors. This state is the result of aneuploid cancer cells undergoing whole genome doubling and skippi
Objectives: This study aims to evaluate how metastases in the seven topographical regions of the simplified peritoneal cancer index (sPCI) affect the survival of patients treated with cytoreductive surgery (CRS) and heated intraperitoneal chemotherapy (HIPEC) for peritoneal carcinomatosis (PC) from colorectal (CRC) or appendiceal cancers.Methods: Data was collected retrospectively from patient rec
OBJECTIVE: We investigated whether certain occupations were over-represented among surgically treated carpal tunnel syndrome and ulnar entrapment at the elbow, and if manual occupation affected surgical outcome.METHODS: We included 9030 patients operated for CTS and 1269 for UNE registered in the Swedish National Quality Register for Hand Surgery (HAKIR) 2010-2016. Occupational data was retrieved
Visual opsins of vertebrates and invertebrates diversified independently and converged to detect ultraviolet to long wavelengths (LW) of green or red light. In both groups, colour vision largely derives from opsin number, expression patterns and changes in amino acids interacting with the chromophore. Functional insights regarding invertebrate opsin evolution have lagged behind those for vertebrat
The present National Innovation Policy (henceforth called PNI) was instituted in Brazil by Decree No. 10.537, of October 28, 2020, within the federal public administration. The policy's objective is to guide, coordinate and articulate strategies, programs, and actions across several public entities to foster innovation in the productive sector. Thus, it aims to increase the productivity and compet
Aims: Bioactive adrenomedullin (bio-ADM) is a vascular-derived peptide hormone that has emerged as a promising biomarker for assessment of congestion in decompensated heart failure (HF). We aimed to evaluate diagnostic and prognostic performance of bio-ADM for HF in comparison to amino-terminal pro-B-type natriuretic peptide (NT-proBNP), with decision thresholds derived from invasive haemodynamic
The dramatic increase in accessibility to sequencing technologies has opened new avenues into studying different processes, cells, and animal models. In the amphibian models used for regeneration research, these new datasets have uncovered a variety of information about what genes define the regenerating limb as well as how genes and cells change over the course of regeneration. The accumulation o
Type 1 diabetes (T1D) is an autoimmune disease that results in the destruction of insulin producing pancreatic β-cells. One of the genes associated with T1D is TYK2, which encodes a Janus kinase with critical roles in type-Ι interferon (IFN-Ι) mediated intracellular signalling. To study the role of TYK2 in β-cell development and response to IFNα, we generated TYK2 knockout human iPSCs and directed
Women tend to have lower interest in engineering as compared to men, which previous research has shown is partly explained by gender differences in self-efficacy, social belongingness and communal career goals. Therefore, to attract more women to engineering, effective interventions are needed that target these factors. In this study, we evaluated an industry-designed intervention for high school
Over the past decade, our understanding of brain-waste clearance underwent a revolution after the discovery of the so-called glymphatic system. The glia-lymphatic (abbreviated, glymphatic) system was first described in 2012 as a paravascular macrosystem involved in the distribution of nutrients and clearance of metabolic waste from the brain parenchyma. The main actor of the system is the cerebros
We are developing techniques for studying the Rayleigh-Taylor (RT) and Richtmyer-Meshkov (RM) instabilities in a planar geometry at high-energy-densities at the National Ignition Facility (NIF). In particular, through the improvement of experimental imaging quality, we are progressing toward the study of the turbulent regime of the mixing regions in capsule implosion experiments for inertial confi
Abstract in TurkishHazreti Muhammed’in ailesi (Ehl-i Beyt), Şii mezhebi inancında merkezi bir konuma sahiptir. Bu dünyada şefaat edebilecek gayri maddi varlıklar olarak, Müslümanların hayatlarına tanık oldukları ve onlarla birlikte bulundukları söylenir. Ne yazık ki antropolojide, bu gibi gayri maddi ve insan-ötesi varlıklarla ilişkiler ihmal edilmektedir. Bu makale, insan-ötesi varlıkları sadece The Family of the Prophet Muhammad holds a central position in Shiʿi Muslim religiosity. As immaterial beings able to intercede in this world, they are said to be witnessing and co-present in the lives of Muslims. Anthropology has neglected relations with immaterial more-than-human beings like these. Instead of regarding them merely as symbols or moral exemplars, this essay focuses on the cultivat
Research shows that much of the blame for waste and lost resources can be traced to the design phase. The implementation of Circular Economy (CE) has the potential to reduce waste by encouraging reuse of resources in a closed loop. Given that designers are involved in the design process, this paper investigates whether they are properly equipped to take responsibility for the shift toward CE. A gr
Failure and stiffness properties of a woven 8 harness satin (8HS) graphite/PMR-15 composite have been investigated at room temperature and at 315°C by performing the ±45° tensile and Iosipescu tests. Acoustic emission has been monitored during testing. The critical loads for the initiation of damage in the composite have been determined. In particular, the specimen width effect has been investigat
AIMS: Proneurotensin (Pro-NT) is a strong predictor of cardiometabolic disease including type 2 diabetes and obesity, however, the effect of lifestyle change on Pro-NT has not been investigated in this context. Middle Eastern (ME) immigrants represent the largest and fastest growing minority population in Europe and are a high-risk population for obesity and type 2 diabetes. In this randomised con
Preterm infants are at high risk of developmental disability/delay and are more dependent on their caregiving environment for regulation due to their neurological immaturity. A premature birth is also a major stressor to the family system that constitutes the infant’s caregiving environment. The following systematic review investigates whether families with preterm children differ from families wi
