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We investigate whether number of episodes (NoEs) meaningfully reflect genetic risk and genetic heterogeneity for five primary disorders—Drug Use Disorder (DUD), Alcohol Use Disorder (AUD), Major Depression (MD), Bipolar Disorder (BD), and Schizophrenia (SZ) ascertained from Swedish population registries. We utilize Genetic Risk Ratios (GRR)—defined as the ratio of the genetic risk for secondary di
A comprehensive approach to ecological functional zoning in the Shenzhen region of China is presented in this study. Through the integration of advanced geospatial analysis tools, multiple data sources, and sophisticated statistical techniques, different ecological functions have been identified and categorized based on a comprehensive set of indicators and spatial analysis techniques. The three-l
A partial ichthyosaur skeleton from the Toarcian (Lower Jurassic) bituminous shales of the ‘Schistes Carton’ unit of southern Luxembourg is described and illustrated. In addition, associated remnant soft tissues are analyzed using a combination of imaging and molecular techniques. The fossil (MNHNL TV344) comprises scattered appendicular elements, together with a consecutive series of semi-articul
How well patient perceived outcome reflects clinical measurements after arthroscopic lysis and lavage of the temporomandibular joint (TMJ) is not fully understood.The purpose of this study was to detect any correlation between patient reported outcome measures (PROM) and clinical follow-up measurements.Patients with internal derangement of the TMJ treated with arthroscopic lysis and lavage 2014–20
Light-level geolocators were used to record the annual migration cycles of black terns Chlidonias niger (9 individuals, 11 journeys) and common terns Sterna hirundo (7 individuals, 11 journeys) breeding in southernmost Sweden. The black terns used two different non-breeding (Oct–Mar) regions along the Atlantic coast of Africa, either north of the equator between Senegal and Liberia (3 individuals)
This article employs a holistic understanding of environmental, social, and economic sustainability to explore the interaction between neoliberalism, climate crisis, digitalization, and academic work with a focus on its everyday aspects. Drawing our experience of organizing an online conference during the Covid-19 pandemic and our dialogue with conference participants, we first problematize the pr
BACKGROUND: Telomere length (TL) and mitochondrial DNA copy number (mtDNAcn) variations are linked to age-related diseases and are associated with environmental exposure and nutritional status. Limited data, however, exist on the associations with mercury exposure, particularly early in life.OBJECTIVE: We examined the association between prenatal mercury (Hg) exposure and TL and mtDNAcn in 1,145 S
Computational dosimetry using Monte Carlo radiation transport simulations was applied for the 2019 European Radiation Dosimetry Group (EURADOS) and Running the European Network of Biological and retrospective Physical dosimetry (RENEB) field test, an exercise of retrospective dosimetry techniques for a realistic small-scale radiological accident. The simulations were performed at four institutes,
For linear time-invariant systems with uncertain parameters belonging to a finite set, we present a purely eterministic approach to multiple-model estimation and propose an algorithm based on the minimax criterion using constrained quadratic programming. The estimator tends to learn the dynamics of the system, and once the uncertain parameters have been sufficiently estimated, the estimator behave
Weakly-hard models have been used to analyse real-time systems subject to patterns of deadline hits and misses. However, the tools that are available in the literature have a set of shortcomings. The analysis they offer is limited to a single weaklyhard constraint and to patterns that specify the number of misses, rather than the number of hits. Furthermore, the scalability of the tools is limited
BACKGROUND: Data in national health care quality registries must be valid and reliable in order to enable open comparisons of results.AIM: To assess the reliability of data on percent consonants correct (PCC) and its associated quality indicator ≥86% correct consonants in the Swedish quality registry for patients born with cleft lip and palate (CLP) registry.METHODS: Six independent speech-languag
A corpus study and a combined behavioural and neurophysiological study tested how phonetic and phonological features of the Danish creaky voice feature ‘stød’ influence predictive processing. Being associated with certain word endings, stød and its modal voice counterpart non-stød can cue upcoming speech. Stød has two phases. The first shows phonetic differences in pitch while the second, characte
A Caucasian female patient in her 90s was referred to the department of plastic and reconstructive surgery for surgical removal of a large invasive squamous cell carcinoma on the anterior chest wall. A skin biopsy prior to the referral indicated that the tumour was moderately differentiated. The patient suffered from severe congestive heart failure with a mechanical valve prosthesis and atrial fib
In this letter, we give an upper bound on the deviation from H-infinity optimality of a class of controllers as a function of the deviation from symmetry in the state matrix. We further suggest a scalar measure of symmetry which is shown to be directly relevant for estimating nearness to optimality. In connection to this, we give a simple analytical solution to a class of Lyapunov equations for tw
This article briefly discusses the notion of input in a study abroad perspective, situating it against how input is treated in second language acquisition (SLA) more broadly, with a focus on methodological issues, operationalizations, and measurements. It further introduces three studies that examine input as studied in ‘the real wild’, and two studies that instead focus on ‘the digital wild’.
The article explores how the global Cold War conflict was made sense of and situated in local political, cultural and physical landscapes and communities during the 1980s in Britain and Denmark. Using civil defence as a prism, the article employs a comparative approach to explore variations within and between countries of how local authorities prepared or resisted the prospect of nuclear war. The
Estimated glomerular filtration rate (eGFR) reflects kidney function. Progressive eGFR-decline can lead to kidney failure, necessitating dialysis or transplantation. Hundreds of loci from genome-wide association studies (GWAS) for eGFR help explain population cross section variability. Since the contribution of these or other loci to eGFR-decline remains largely unknown, we derived GWAS for annual
Reconstruction of movement control properties of the brain could result in many potential advantages for application in robotics. However, a hampering factor so far has been the lack of knowledge of the structure and function of brain circuitry in vivo during movement control. Much more detailed information has recently become available for the area of the cerebellum that controls arm-hand movemen
