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Systemic immunization with soluble flagellin (sFliC) from Salmonella Typhimurium induces mucosal responses, offering potential as an adjuvant platform for vaccines. Moreover, this engagement of mucosal immunity is necessary for optimal systemic immunity, demonstrating an interaction between these two semi-autonomous immune systems. Although TLR5 and CD103+CD11b+ cDC2 contribute to this process, th
Future applications of internet of things (IoT) will go far beyond connecting sensors to the internet. The real challenge lies in how to easily build well working systems of things: well integrated distributed applications that support users, yet built from a variety of devices running on a variety of networks and protocols, and including services that were not designed to interoperate.Based on ou
Modern transportation requires advanced powertrain systems to reduce the production of greenhouse gas CO2. Partially premixed combustion (PPC) is one of the most promising methods to achieve low emission and low fuel consumption of internal combustion engines. The present paper evaluated the effects of the calibration parameters on the efficiency and emissions of a multi-cylinder engine using PPC
This paper introduces a predictive combustion-engine controller for efficient fulfillment of constraints on peak pressure, exhaust temperature and NO emissions. The controller utilizes a in-cylinder pressure sensor, actuation of multiple fuel injections and numerical optimization. A physical model is used to predict pressure changes due to fuel-injection variation. The predicted pressure is used t
Partially premixed combustion (PPC) is a hybrid combustion of Homogeneous Charge Compression Ignition (HCCI) and Diesel Combustion (DC), which has a great potential in reducing the fuel consumption. PPC has a longer premixed time than DC but lesser than HCCI. Therefore it is more stratified than HCCI. This paper first presents results on how the stratification using multiple injections and differe
Protein diffusion is not only an important process ensuring biological function but can also be used as a probe to obtain information on structural properties of protein assemblies in liquid solutions. Here, we explore the oligomerization state of ovalbumin at high protein concentrations by means of its short-time self-diffusion. We employ high-resolution incoherent quasielastic neutron scattering
Blind people may detect objects from the information in reflected sounds, echolocation. Detection as a function of the number of clicks compared to a continuous noise was tested by presenting clicks of 5 ms with rates from 1 to 64 clicks during a 500 ms period and a 500-ms continuous white noise. The sounds were recorded in an ordinary room through an artificial binaural head. The reflecting objec
Custom architectures are often adopted as more efficient alternatives to general purpose processors in terms of performance and power. However, the design of such architectures requires experts both in hardware and the application domain. In this paper we propose a method for speeding up the design space exploration. Our method, based on Pareto points, identifies sets of solutions in terms of scal
Using ultralow-power wake-up receivers (WRxs) can reduce idle listening energy cost in wireless sensor networks with low traffic intensity. This has led to many WRx analog front-end (AFE) designs presented in literature, with a large variety of trade-offs between the sensitivity, the data rate, and the power consumption. Energy consumed during wake-up in a network depends on many parameters and wi
This contribution presents a novel model-based methodology for open-loop optimal control of batch high-pressure liquid chromatographic (HPLC) separation processes. The framework allows for simultaneous optimization of target component recovery yield and production rate with respect to a parameterization of the input elution trajectory and fractionating interval endpoints. The proposed methodology
Partially premixed combustion (PPC) is a low temperature, direct-injection combustion concept that has shown to give promising emission levels and efficiencies over a wide operating range. In this concept, high EGR ratios, high octane-number fuels and early injection timings are used to slow down the auto-ignition reactions and to enhance the fuel and are mixing before the start of combustion. A d
The computation power we expect from the various smart devices we use keeps increasing. Not only do we want faster devices but also less power hungry and energy efficient devices, both for the environment and our personal convenience (remember that "mobile phone" attached to a power plug at all times?).One way of addressing this demand is to build custom processor architectures that focus on a spe
Splatting photons onto primary view samples, rather than gathering from a photon acceleration structure, can be a more efficient approach to evaluating the photon-density estimate in interactive applications, where the number of photons is often low compared to the number of view samples. Most photon splatting approaches struggle with large photon radii or high resolutions due to overdraw and insu
A detailed understanding of the dynamic processes of vehicular radio channels is crucial for its realistic modeling. In this paper, we present multipath components (MPCs) tracking results from a channel sounder measurement with 1-GHz bandwidth at a carrier frequency of 5.7 GHz. We describe in detail the applied algorithms and perform a tracking performance evaluation based on artificial channels a
Realistic propagation modeling requires a detailed understanding and characterization of the radio channel properties. This paper is based on channel sounder measurements with 1 GHz bandwidth at a carrier frequency of 5.7 GHz and particular tracking methods. We present statistical models for the number of, birth rate, lifetime, excess delay and relative Doppler frequency of individual multipath co
BACKGROUND: Although the association between cytosine-adenine-guanine (CAG) repeat length and age at onset of Huntington's disease is well known, improved prediction of onset would be advantageous for clinical trial design and prognostic counselling. We compared various measures for tracking progression and predicting conversion to manifest Huntington's disease.METHODS: In this prospective observa
Application of the faster than Nyquist signaling method to the upcoming fifth generation wireless system
Methods for energy and bandwidth efficient coded digital communication, including pulse design, non-orthogonal signaling methods, and the faster than Nyquist signaling method.
