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Background: Although effective return-to-work (RTW) interventions are not widely available for individuals with common mental disorders on sick leave, there is potential for transforming such interventions into a digital solution in an effort to make them more widely available. However, little is currently known about the viewpoints of different stakeholder groups, which are critical for successfu

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To figure out the abnormal flow characteristics and thermal performance of supercritical fluids, some detailed information of supercritical pressure n-decane flowing in a horizontally round pipe is studied in terms of secondary flow induced by the huge density change or buoyancy force. According to an evaluation of turbulence models, the shear stress transport k-ω is suitable to execute the case o

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Background Coronavirus disease 2019 (COVID-19) is a rapidly spreading disease that has caused extensive burden to individuals, families, countries, and the world. Effective treatments of COVID-19 are urgently needed. Methods and findings This is the first edition of a living systematic review of randomized clinical trials comparing the effects of all treatment interventions for participants in all

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OBJECTIVES: Low or high sympatho-adrenal-medullary axis (SAM) and hypothalamic-pituitary-adrenal axis (HPA) dysregulation reflect chronic stress. Retinal vessel dynamics may relate to SAM, HPA activity and stroke risk. Our objectives were therefore to assess the relationships between retinal vessel, SAM and HPA responses, and to determine stroke risk.METHODS: A prospective bi-ethnic gender cohort

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This paper presents a search for new heavy particles decaying into a pair of top quarks using 139 fb−1 of proton-proton collision data recorded at a centre-of-mass energy of s = 13 TeV with the ATLAS detector at the Large Hadron Collider. The search is performed using events consistent with pair production of high-transverse-momentum top quarks and their subsequent decays into the fully hadronic f

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Objective: To evaluate mid-term survival in patients undergoing elective fenestrated endovascular aneurysm repair and standard endovascular aneurysm repair for abdominal aortic aneurysm. Methods: Consecutive patients treated from 2007 to 2011 with elective fenestrated endovascular aneurysm repair (n = 81) and endovascular aneurysm repair (n = 201) were evaluated concerning age, cardiovascular medi

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In the present work Optimal Power Flow (OPF) with minimum net work losses for Iraqi National Super Grid (400kv) INSG which consist of 19 load buses and 6 generating buses was studied. The losses were calculated and compared with that in case of ordinary load flow which is equal to 37592 MW according to data of generation and load on 2/1/2003.Mathematical model using Lagrange method programmed in M

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Purpose: To investigate case mix in relation to capsule complication, possible associations between case mix and operation volume, and change in case mix over time. Design: Register-based study. Participants: Swedish patients who underwent cataract surgery between 2007 and 2016. Methods: Demographics and data on ocular comorbidity, intraoperative difficulties, and capsule complications were regist

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The societal costs of disasters around the world are continuing to increase and Pacific Island countries are considered some of the most vulnerable. This is primarily due to a combination of high hazard exposure coupled with a range of social, economic, physical, and political vulnerabilities. This article contributes to the growing body of work that aims to understand the causal factors of disast

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This chapter examines the role that legal actors can play in promoting accountability for, and thereby potentially contributing to the reduction in the incidence of sexual assault in situations of disaster displacement, particularly in evacuation centres and temporary shelters. It argues that justice-sector actors can contribute to accountability for and a reduction in sexual assault in evacuation

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This article provides a rationale for inner transformation as a key and hitherto underresearched dimension of sustainability transformations. Inner transformation relates to various aspects of human existence and interactions such as consciousness, mindsets, values, worldviews, beliefs, spirituality and human–nature connectedness. The article draws on Meadows’ leverage points approach, as places t

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This paper reports on Monte Carlo simulation results for future measurements of the moduli of time-like proton electromagnetic form factors, | GE| and | GM| , using the p¯ p→ μ+μ- reaction at P ¯ ANDA (FAIR). The electromagnetic form factors are fundamental quantities parameterizing the electric and magnetic structure of hadrons. This work estimates the statistical and total accuracy with which th

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The main goal of this article is to evaluate the relationship between the spatial distribution of the population of the city of Belo Horizonte, one of the largest cities in South America, and its public transport network, seeking to ascertain whether the current bus network is able to meet the needs of the population. The methodology was based on data processing and vector information from differe

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Lipidomics can complement genomics and proteomics by providing new insight into dynamic changes in biomembranes; however, few reports in the literature have explored, on an organism-wide scale, the functional link between nonenzymatic proteins and cellular lipids. Here, we report changes induced by adenovirus-delivered wild-type p53 gene and chemotherapy of U87 MG glioblastoma cells, a treatment k

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The S-HELP Decision Support System was developed in a fp7 EU project for improving preparedness, response, and interoperability of health services and other main stakeholders involved in emergency situations (http://www.fp7-shelp.eu/project). We, the team of the University of Vienna, investigated emergency interventions/tasks performed by emergency responders (skills taxonomy) using emergency mate

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Background/Aims: Whether age at onset influences functional deterioration in Alzheimer disease (AD) is unclear. We, therefore, investigated risk factors for progression in activities of daily living (ADL) and nursing home placement (NHP) in cholinesterase inhibitor (ChEI)-treated patients with early-onset AD (EOAD) versus late-onset AD (LOAD). Methods: This 3-year, prospective, observational, mult

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Diamond-Blackfan anemia is a congenital erythroid hypoplasia and is associated with physical malformations and a predisposition to cancer. Twenty-five percent of patients with Diamond-Blackfan anemia have mutations in a gene encoding ribosomal protein S19 (RPS19). Through overexpression of RPS19 using a lentiviral vector with the spleen focus-forming virus promoter, we demonstrated that the Diamon

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A measurement of the calorimeter response to isolated charged hadrons in the ATLAS detector at the LHC is presented. This measurement is performed with 3.2 nb- 1 of proton–proton collision data at s=7 TeV from 2010 and 0.1 nb- 1 of data at s=8 TeV from 2012. A number of aspects of the calorimeter response to isolated hadrons are explored. After accounting for energy deposited by neutral particles,

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Cytochrome 5558 in the cytoplasmic membrane ofBacilius subtiiis constitutes the anchor and electronacceptor to the flavoprotein (Fp) and iron-sulphurprotein (Ip) in succinate:quinone oxidoreductase, andseemingly contains two haem groups. EPR and MCDspectroscopic data indicate bis-imidazole ligation ofthe haem. Apo-cytochrome was found in the mem-brane fraction of haem-deficient B. subtilis, sugges