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Objective: Several surgical approaches are being used in the reconstruction of long-gap esophageal atresia. We investigated which methods are being used in the Nordic countries and the postoperative complications that occurred in the first year of life. Methods: This study is a retrospective multicenter study, where medical records on children with esophageal atresia Gross type C or D born in the
Humans have an irresistible inclination to coordinate actions with others, leading to species-unique forms of cooperation. According to the highly influential Shared intentionality theory (SITh), human cooperation is made possible by shared intentionality (SI), typically defined as a suite of socio-cognitive and motivational traits for sharing psychological states with others, thereby enabling ind
INTRODUCTION: Children and adolescents are encouraged to maintain a habitually active lifestyle because of the known health benefits associated with regular physical activity, but there are some reports that a high level of activity may be associated with increased fracture risk. This prospective controlled exercise intervention study in pre-pubertal children evaluated if a school-based exercise i
Background The zinc transporter 8 (ZnT8) was recently identified as a common autoantigen in type 1 diabetes (T1D) and inclusion of ZnT8 autoantibodies (ZnT8Ab) was found to increase the diagnostic specificity of T1D. Objectives The main aims were to determine whether ZnT8Ab vary during follow-up 1 year after diagnosis, and to relate the reactivity of three types of ZnT8Ab to the residual stimulate
A key fatty acid synthesis enzyme, acetyl-CoA carboxylase alpha(ACC-alpha), has been shown to be highly expressed in human breast cancer and other tumor types and also to specifically interact with the protein coded by one of two major breast cancer susceptibility genes BRCA1. We used a comprehensive haplotype analysis to examine the contribution of the ACC-alpha common genetic variation (allele f
Objective. Insulin resistance is associated with progression of atherosclerosis. We assessed the effect of 12 months of treatment with rosiglitazone (RSG) on the progression of carotid intima-media thickness (IMT) in people with type 2 diabetes mellitus (T2DM) or the insulin resistance syndrome (IRS). Design. Randomized, double-blind, placebo-controlled trial. Setting. Malmo University Hospital, M
Micro-organisms are used industrially by humans, to improve production, either qualitatively or quantitatively, and to enhance profit or value. In cheese production, the starter bacteria hydrolyse casein degradation products generated by rennet. Some bitter peptides accumulate during cheese ripening, and their degradation would improve the flavour of the cheese. Plasmid pHP003 from the starter st
In this study we investigated whether single nucleotide polymorphisms (SNP) in the genes coding for BDNF (Val66Met) and VEGF (C2578A) may be associated with maladaptive strategies among suicide attempt patients. We found that BDNF Val66Met gene polymorphism probably affect avoidant coping strategies.
Early signal relay steps upon ligand binding to the receptor tyrosine kinase Flt3, i.e. sites of Flt3 autophosphorylation and subsequent docking partners, are mainly unresolved. By immunoprecipitation of specific tryptic peptides contained in the juxtamembrane region of human Flt3 and subsequent radiosequencing we identified the tyrosine residues 572, 589, 591 and 599 as in vivo autophosphorylatio
In a prospective pilot study nested in the EPIC-Oxford cohort, we examined the seroprevalence of antibodies against the L1 antigen of 38 human papilloma virus (HPV) types among 39 cases of cutaneous squamous cell carcinoma (SCC) for whom plasma was collected prior to diagnosis (incident) and 80 controls. Fifteen cases having already developed SCC at blood collection (prevalent) were also tested. T
In an attempt to identify diagnostically meaningful subgroups in a group of sixty women 18–34 years of age, 19 of them having a DSM-IV diagnosis of anorexia nervosa and 41 of bulimia nervosa, a hierarchical cluster analysis was performed on their data obtained from the Defense Mechanism Technique modified (DMTm) and the Eating Disorder Inventory (EDI). Variables also taken into account in the clus
In an attempt to identify subtypes of breast cancer and pinpoint patterns of cell cycle regulatory defects associated with clinical behaviour, proliferation and other transformation associated events, a multitude of cell cycle regulatory proteins were analysed in a material of 113 primary breast cancers. Increased proliferation was observed in two different scenarios; (1) with high cyclin D1 and e
Lectotypes are designated for 174 names of taxa described based on material from the Swedish province of Dalarna and accepted to belong to Hieracium sect. Hieracium, sect. Bifida and sect. Vulgata. The taxonomic and nomenclatural implications, i.e. taxonomic synonyms and infraspecific taxa not worthy of taxonomic recognition, of the lectotypifications are discussed. Three new combinations, H. mund
Background Combined oral contraceptives are classified by the International Agency for Research on Cancer as a cause of cervical cancer. As the incidence of cervical cancer increases with age, the public-health implications of this association depend largely on the persistence of effects long after use of oral contraceptives has ceased. Information from 24 studies worldwide is pooled here to inves
This study aims to increase the knowledge and understanding regarding the situation for undocumented immigrants in the Scandinavian welfare states, mainly from a Swedish perspective, but the situation in Denmark is also included in the discussion. Sweden and Denmark position themselves at the opposite sides of the spectrum regarding immigration policies within the European Union; Swedish immigrati
”The economy as instituted process” från 1957 torde vara den näst mest kända texten av Karl Polanyi (1886–1964) efter hans huvudarbete Den stora omdaningen från 1944. Här reder han ut skillnaden mellan ekonomibegreppets två innebörder av ekonomi som människors faktiska, substantiella utbyte med naturen och varandra och ekonomi som ett formaliserat tankesystem för rationell optimering. Polanyi argu
