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Epilepsy is a family of heterogeneous and multifactorial neurological disorders, unified by the occurrence of spontaneous recurrent seizures. Overall, it affects 50 million people worldwide of all ages and genders. Available treatments are only symptomatic and have severe side effects, while they also fail to provide adequate seizure control in a third of the patients. Therefore, a cure is yet to

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Sixteen landcover classes in a representative Swedish environment were analyzed and classified using one Landsat TM scene and seven ERS-1 SAR.PRI images acquired during 1993. Spectral and backscattering signature separabilities are analyzed using the Jeffries-Matusita distance measure to determine which combinations of channels/images contained the most information. Maximum likelihood, sequential

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We introduce the combination of digital holographic microscopy (DHM) and antibody microarrays as a powerful tool to measure morphological changes in specifically antibody-captured cells. The aim of the study was to develop DHM for analysis of cell death of etoposide-treated suspension cells. Results/methodology: We demonstrate that the cell number, mean area, thickness and volume were noninvasivel

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AIM: The aim of this study was to determine the value of medical history and physical examination, tumour marker testing, and CT-scanning in the follow-up of patients treated for peritoneal carcinomatosis of colorectal origin.METHODS: Between November 1995 and June 2003, 107 patients were treated by cytoreduction and hyperthermic intra-peritoneal chemotherapy. The treatment was considered effectiv

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Purpose of Review: Recent advances in the small field of the rare mixed phenotype acute leukemias (MPAL) are presented focusing on a better understanding of their pathophysiology and search for better therapeutic approaches. Recent Findings: Three aspects of respective classification, therapy, and immunophenotype of MPAL are reviewed. New proposals have been made to segregate MPAL subtypes based o

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Arsenic contamination of drinking water is a result of natural and/or anthropogenic activities, causing undesirable detrimental effects on the environment and the human health. Herein, an integrated process based on Membrane Distillation (MD), photocatalysis and Polymer-enhanced Ultrafiltration (PEUF) was developed for an effective remediation of arsenic (As). This approach, whose effectiveness wa

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Smooth muscle participates in forming the wall of hollow organs, tracts, and blood vessels. Therefore, it plays a critical role in mediating vital functions in the body including regulation of blood pressure. In response to changes in the surrounding microenvironment, smooth muscle cells can modulate their phenotype and dedifferentiate from being quiescent contractile to a more proliferative and m

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Agarose hydrogels have been extensively used as a phantom material to mimic the mechanical behavior of soft biological tissues, e.g. in studies aimed to analyze needle insertions into the organs producing tissue damage. To better predict the radial stress and damage during needle insertions, this study was aimed to determine the friction coefficient between the material of commercial catheters and

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Over the past couple of decades, increased interdependencies between and institutional defragmentation of, our Critical Infrastructures (CIs) have created a setting were traditional risk management might no longer suffice. In particular, analysis and management of risks have evolved from being a predominantly intra-organisational task towards a process that also requires inter-organisational coord

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Background: The incidence of invasive cutaneous melanoma (CM) is increasing in Sweden. The aim was to present age-and sex-specific trends of the age-standardised incidence and the average annual percentage change (AAPC) for in situ and invasive CM. Methods: Joinpoint regression models were used to analyse data from the Swedish Cancer Register and the Swedish Melanoma Registry 1997–2018 (N = 35,350

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The focus of this study was the empirical modelling of the high-speed bearings life and failure modes of a through-flow universal motor. An approach was used facilitating predictions of the life through-range of various conditions. The model estimates bearing life for the survival probability of 50% – L50. It influences parameters such as bearing temperature, speed factor, equivalent load, grease

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Purpose: Monte Carlo (MC) modelling techniques can assess the quantitative accuracy of both planar and SPECT Nuclear Medicine images. It is essential to validate the MC code's capabilities in modelling a specific clinical gamma camera, for radionuclides of interest, before its use as a clinical image simulator. This study aimed to determine if the SIMIND MC code accurately simulates emission image

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While an extensive part of the conflict transformation literature stresses the importance of transforming the identities of conflict parties through recognition, it fails to recognise the propensity of such transformations to generate ontological insecurity and dissonance, and consequently a possible backlash towards antagonistic identities. Drawing on agonistic thought, we develop a conception of

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Chemical, oxidational and diffusional interactions between the tool, chip and cutting environment are known tool wear mechanisms in machining. However, the interaction between tool, coating, workpiece, coolant and atmospheric oxygen can, under favorable conditions, lead to formation of reaction products that retard tool wear. A method with the ability to predict theses interactions, would therefor

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A novel and effective approach for determining mechanics and residual stress when turning a component with curved surfaces is presented in this paper. This predictive approach is based on a three-dimensional analytical model to study the distributed mechanics and residual stress caused by vary cutting condition during the machining process. The variation of uncut chip area in this process can be d

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Context. Despite swift progress in the characterisation of exoplanet atmospheres in composition and structure, the study of atmospheric dynamics has not progressed at the same speed. While theoretical models have been developed to describe the lower layers of the atmosphere, and independently, the exosphere, little is known about the intermediate layers up to the thermosphere. Aims. We aim to prov

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Wastewater heat recovery upstream of wastewater treatment plants (WWTP) poses a risk to treatment performance, i.e. the biological processes. In order to perform a sustainability analysis, a detailed prediction of the temperature dynamics over the WWTP is needed. A comprehensive set of heat balance equations was included in a plant-wide process model and validated for the WWTP in Linköping, Sweden

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Vi välkomnar repliken från Carbon Capture Companys vd. Vi, EU, Sveriges regering och Christoffer Bonde delar målet att främja ett starkt och lönsamt skogsbruk som bidrar till klimat­arbetet både genom upptag av växthus­gaser och minskade utsläpp. Vad vi ställer oss kritiska till är den klimat­kompensation som just nu lanseras av företag som Carbon Capture Company, eftersom vi anser att den är dyr,

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Trees have the potential to improve urban air quality as leaves and needles capture air pollutants from the air, but further empirical data has been requested to quantify these effects. We measured the concentration of 32 polycyclic aromatic hydrocarbons (PAHs) in leaves of pin oak (Quercus palustris) and needles of black pine (Pinus nigra) in the City of Gothenburg, Sweden, during the summer of 2