Filtyp
DNA is a versatile heteropolymer that shows great potential as a building block for a diverse array of nanostructures. We present here a solution to the problem of designing and synthesizing a DNA-based nanostructure that will serve as the track along which an artificial molecular motor processes. This one-dimensional DNA track exhibits periodically repeating elements that provide specific binding
Background: There is a lack o educational material for adults with congenitally malformed hearts. Computer-based education has shown to have significant effects on knowledge and management of chronic diseases. Aim: The aim of this study was to develop and evaluate a computer-based educational program for adults with congenitally malformed hearts. Methods: The program was developed by a multidiscip
Six strains isolated from fermented food were by 16S rDNA sequencing identified as Weissella species, clustering with the species-pair W. confusa/ W. cibaria. The strains were analysed for growth on glucose, xylose and xylooligosaccharides (XOS). All strains were xylose positive using the API CHL 50 test. Growth on XOS was observed for strain 85, 92, 145 and AV1, firstly by optical density measure
Perfluoroalkyl acids (PFAAs) are a large group of chemicals which are highly persistent in both nature and humans. The use of the most prominent ones, perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA), was reduced in the early 21st century, and since then levels in human matrices have decreased. However, these two compounds have been exchanged by other PFAAs, for which time trends
This paper reports for the first time the application of sol-gel microarrays for immobilizing nonsoluble small chemicals (Bisphenol-A; BPA). Also, known problems of sol-gel adhesion to conventional microtiter well plate substrates are circumvented by anchoring the sol-gel microspots to a porous silion surface so-called, PS-SG chips. We confirmed low molecular weight chemical immobilization inside
The application of detailed chemistry to the computational fluid dynamics simulation of combustion process in diesel engines has many potentials, including the possibility to predict auto-ignition, diffusion flame structure, stabilisation and soot formation in a wide range of operating conditions, also taking into account the effects of different fuel types. Among the approaches that were proposed
Within the family of voltage-gated calcium channels (VGCCs), L-type channels (L-VGCCs) represent a well-established therapeutic target for calcium channel blockers, which are widely used to treat hypertension and myocardial ischemia. L-VGCCs outside the cardiovascular system also control key physiological processes such as neuronal plasticity, sensory cell function (e.g. in the inner ear and retin
We have measured radiative lifetimes for selenium and tellurium resonance levels by using short pulse laser excitation in differentially heated resonance cells. We obtained tau(3S1 Se I) = 2.9(5) ns and tau(3S1 Te I) = 3.1(5) ns, which together with branching ratio values given by Ubelis and Berzinsh yield the absorption oscillator strength f(abs)(Se I, 196.0 nm) = 0.074(16) and f(abs)(Te I, 214.3
A modified Delphi method was used to determine thresholds for Minimum Data Set quality indicators for Icelandic nursing homes. The thresholds were then applied to quality outcomes in Icelandic nursing homes for the year 2009. The thresholds indicate areas of good or poor care and can be used for planning services. Icelandic nursing homes seem to be doing best in incontinence and nutritional care.
Consider a reflected random walk Wn+1 = (W-n +X-n)(+), where X-o, X-1,... are i.i.d. with negative mean and subexponential with common distribution F. It is shown that the probability that the maximum within a regenerative cycle with mean mu exceeds x is approximately mu (F) over bar(x) as x --> infinity, and thereby that max (W-o,..., W-n) has the same asymptotics as max(X-o,...,X-n) as n --> inf
To increase our understanding of the genetic basis of adiposity and its links to cardiometabolic disease risk, we conducted a genome-wide association meta-analysis of body fat percentage (BF%) in up to 100,716 individuals. Twelve loci reached genome-wide significance (P<5 × 10(-8)), of which eight were previously associated with increased overall adiposity (BMI, BF%) and four (in or near COBLL1/GR
This paper presents an innovative research on urban risk reduction and climate change adaptation that combines case studies, grounded theory and systems analysis, which could be used as a template for similar intersectoral and interdisciplinary investigations. Such a ‘case studies–grounded theory–systems analysis approach’ permits a grounded theory to be built from case study data, which is viewed
Given an electronic wave function, generated by the MCHF program (LS format) or the MCHF_CI program (LSJ format), this program computes the hyperfine interaction constants, A(J) and B(J). In strong experimental magnetic fields, the splitting is also affected by the off-diagonal hyperfine constants A(J,J-1), B(J,J-1), and B(J,J-2) and these are computed as well, depending on the input data.
The ambiguity domain plays a central role in estimating the time-varying spectrum of a non-stationary random process in continuous time, since multiplication in this domain is equivalent with estimating the covariance function of the random process using an intuitively appealing estimator. For processes in discrete time there exists a corresponding covariance function estimator. The ambiguity doma
Objective. Serum calcium concentrations have been associated with the risk of malignant disease, especially breast cancer. Thus, determinants of serum calcium concentrations, with special regard to risk factors of breast cancer, are of great interest. Material and methods. Previous studies have either been small or they have not focused on reproductive factors. The present study examined serum cal
In this study, we analysed the ease of use of three computer programs for self-registration of job seekers. The programs were developed in somewhat different activity contexts. The differences found between the programs in two experiments appeared to result from a combination of fewer constraints on individual input demanded by Job Seeker Bank and Af Explore and from the programs’ better adaptatio
Weak convergence of the multivariate point process of upcrossings of several high levels by a stationary Gaussian process is established. The limit is a certain multivariate Poisson process. This result is then used to determine the joint asymptotic distribution of heights and locations of the highest local maxima over an increasing interval. The results are generalized to upcrossings and local ma
Echocardiography has a vital role for diagnosing and monitoring infectious endocarditis. The recently published Swedish guidelines for diagnosis and treatment of infectious endocarditis recommend overuse of transoesophageal echocardiography, which is not supported by the literature. The European Society of Cardiology presents a considerably more appropriate opinion.
