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Background Despite the fact that severe itch is common in many dermatological diseases, the therapeutic arsenal against itching is limited. From neurophysiological experiments, using a new technique termed cutaneous field stimulation, it is known that acute itch can be effectively relieved by stimulation of cutaneous nociceptors. Methods We tested the effects of cutaneous field stimulation (25 mi
Observations of the ultra-sharp-lined, chemically peculiar star chi Lupi taken by the Goddard High Resolution Spectrograph in echelle mode are presented. Thirty-six intervals of the spectral region between 1249 and 2688 Angstrom are covered with resolving powers in the range 75,000-93,000. Line identifications are provided, and the observed spectra are compared with synthetic spectra calculated us
Researchers often aim to make correct inferences both about that which is actually studied (internal validity) and about what the results generalize to (external validity). The language of internal and external validity is not used by everyone, but many of us would agree that intuitively the distinction makes a lot of sense. Two claims are commonly made with respect to internal and external validi
The chapter argues that language, which rests on the sharing of linguistic norms, honest information, and moral norms, evolved through a co-evolutionary process with a pivotal role for intersubjectivity. Mainstream evolutionary models, based only on individual-level and gene-level selection, are argued to be incapable to account for such sharing of care, values and information, thus implying the n
The binaries PSR J1141-6545 and PSR B2303+46 each appear to contain a white dwarf that formed before the neutron star. We describe an evolutionary pathway to produce these two systems. In this scenario, the primary transfers its envelope on to the secondary, which is then the more massive of the two stars, and indeed sufficiently massive later to produce a neutron star via a supernova. The core of
Brown dwarf atmospheres form molecules, then high temperature condensates (corundum, titanates, silicates, and iron compounds), and then low temperature condensates (ices) as they cool down over time. These produce large opacities which govern entirely their spectral energy distribution. Just as it is important to know molecular opacities (TiO, H2O, CH4, etc.) with accuracy, it is imperative to un
BACKGROUND: Prostate-specific antigen (PSA) occurs in different molecular forms in serum: free PSA (fPSA) and complexed PSA (cPSA), the sum of which corresponds to total PSA (tPSA). In addition to tPSA, percent fPSA is widely used in the detection of prostate cancer. Free PSA, approximately 28 kDa, is eliminated by glomerular filtration. Previous data showed that men with end-stage renal dysfuncti
An in-depth article on the controversial artist Boris Lurie.
Return migration is an important phenomenon that involves a large share of all migrants, and has great potential for the enhancement of economic development, for instance through remittances and investments by migrants who are still abroad, and “brain gain” when migrants return with working experience from their former host countries. This paper deals with return migration, by refugee immigrants a
فغانستانا نقض حقوق بشر و حقوق زنان توسط طالبان در تسلط قدرت توسط طالبان و پیامدهای آن. ، پژوهشگر مؤسسه تحقیقابی حقوق و زنان ) (RWIفریما نوابی راهنما: دکتی مورتن کوچ اندرسن مشاور ارشد و پژوهشگر نقض حقوق بشر و حقوق زنان توسط طالبان در افغانستان: تسلط قدرت توسط طالبان و پیامدهای آن گ ۲۰۲۳ دوستانه رائول والنبر انستیتوت حقوق بشر و حقوق بشر پژوهشگر: فریما نوابر ۲۰۲۲ ISBN: 978-91-86910-88-4 گ عنوان بخشر
Natural killer (NK) cells are involved both in control of virus infections and in elimination of tumor cells. Killer immunoglobulin-like receptors (KIRs) either activate or inhibit NK cell-mediated cytolysis, protecting healthy cells from destruction while enabling killing of abnormal cells. To investigate whether KIR genes or genotypes are associated with cervical carcinogenesis, a nested case-co
A pilot-plant study, made to clarify whether biological denitrification is a possible and suitable method for nitrate reduction of drinking water in Sweden is presented. The concentration of nitrate-nitrogen in un-treated water was 10–15 mg/l. The reactor was a 1.2 m aluminium tube with a inner diameter of 0.19 m. 0.75 m was filled with Filtralite®, expanded clay, through which the nitrate-contami
User generated content (UGC) makes up a significant portion of Internet traffic. As opposed to other content, UGC has so far been left outside over-the-top providing network operators content distribution networks (telco-CDN) due to the difficulty in determining optimised placement of such content. The side effect of this is that UGC content is not placed close to end users and therefore occupy un
In the Netherlands, the role of the woman in society has changed drastically in the past century. Furthermore, over the past 50 years, marriage between man and woman lost its dominant position to alternative forms of cohabitation. These developments in society and civil law are also reflect-ed in the Dutch Personal Income Tax Act (PITA) and the Dutch Gift and Inheritance Tax Act (GITA) and will be
Objective: To investigate the causal role of cardiometabolic risk factors in osteoarthritis (OA) using associated genetic variants. Methods: We studied 27,691 adults from the Malmö Diet and Cancer Study (MDCS) and replicated novel findings among 376,435 adults from the UK Biobank. Trait-specific polygenic risk scores for low-density lipoprotein (LDL) and high-density lipoprotein (HDL) cholesterol
This chapter is focusing on membrane applications in the sugar and brewing industries. Both industries are established global industries operating with large process streams and having a wide range of separation needs. Despite these needs, membrane processes are still in their infancy in these two industries. The key challenge of membrane processes in these industries is membrane fouling due to th
Among the major IT security challenges facing organizations is non-malicious employee behavior that nevertheless poses significant threats to an organization's IT security. Using a grounded theory methodology, this paper finds that organizational security behaviors are inherently related to employee assumptions regarding the importance of IT security policy compliance and regarding the reason why
