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Elevated brain levels of apolipoprotein D (ApoD) correlate with improved neurological recovery after experimental stroke. Hence, a pharmacological induction of ApoD in the postischemic brain could be beneficial for recovery after stroke. Here we investigated the effect of Clozapine, a compound that increases the expression of ApoD, in two rat models of experimental stroke. Rats were subjected to p

Systolic tissue Doppler measurements (s') have been used to measure the velocity in myocardial motion and are a valuable tool for evaluating the systolic function of the left and right ventricles. Digestion of food is known to significantly alter hemodynamics and may therefore affect s'. The effect of food intake on s' parameters has not yet been studied. We assessed whether s' is affected by food

Background:Familial nervous system cancers are rare and limited data on familial aspects are available particularly on site-specific tumours.Methods:Data from five Nordic countries were used to analyse familial risks of nervous system tumours. Standardised incidence ratios (SIRs) were calculated for offspring of affected relatives compared with offspring of non-affected relatives.Results:The total

OBJECTIVE: Cholecystectomy is the standard treatment for acute cholecystitis, but in high-risk patients with serious comorbidity and in patients of advanced age there is substantial morbidity and mortality associated with the intervention. In these selected patients, percutaneous cholecystostomy (PCS) is an alternative mode of management. The aim of the present study was to evaluate the outcome of

Identifying the genetic variants that regulate fasting glucose concentrations may further our understanding of the pathogenesis of diabetes. We therefore investigated the association of fasting glucose levels with SNPs in 2 genome-wide scans including a total of 5,088 nondiabetic individuals from Finland and Sardinia. We found a significant association between the SNP rs563694 and fasting glucose

Neurochemical evidence indicates that cognitive impairment in dementia of Alzheimer type (DAT) is related to degeneration of cholinergic neurons in the brain. A pharmacological approach is treatment with a cholinesterase inhibitor such as tetrahydroaminoacridine (THA). THA treatment of 17 patients with DAT was studied with a double-blind crossover design with three types of treatment, THA + lecith

We have studied the influence of bacterial host on the secretion of single-chain Fv antibody fragment (scFv), the production of this antibody fragment as intracellular fusion protein, and the effect of chaperonin coexpression on intracellular antibody expression. Seven bacterial strains were transformed with a vector carrying the genes encoding the variable regions of an anti-CEA scFv antibody and

Chorea-acanthocytosis (ChAc), an autosomal recessive disorder, is associated with cognitive and behavioral abnormalities. Previous studies were focused around exploring the functional annotation of VPS13A gene in ChAc, whereas the genetic labyrinth underlying this disease and plausible drug targets were underexplored. In the present study, we have identified the pivotal genes and molecular pathway

We present a method for estimating fossil fuel methane emissions using observations of methane and ethane, accounting for uncertainty in their emission ratio. The ethane:methane emission ratio is incorporated as a spatially and temporally variable parameter in a Bayesian model, with its own prior distribution and uncertainty. We find that using an emission ratio distribution mitigates bias from us

BackgroundWe aimed to fill the gaps of knowledge concerning incidence rates and temporal trend, clinical features and risk factors for death for M. morganii bloodstream infections in south Sweden.MethodsThis was an observational, population-based study including all patients with at least one blood culture positive for Morganella morganii between 2013-2023 in Skåne, south Sweden.ResultsA total of

The role of the craftsman, in specific the smith, in the social structure of the Aegean Late Bronze Age

Följande uppsats undersöker ifall principen om respekt för förvärvade rättigheter kan användas för att skydda etableringsfriheten för juridiska personer efter en avtalslöst Brexit. Sedan Storbritanniens folkomröstning har akademiker spekulerat över principens tillämpning för att skydda de rättigheter som härstammar från EU-rätten. Vissa hävdar att principen är tillämplig medan andra hävdar att en This thesis examines if the principle of respect for acquired rights can be used to protect the right of establishment for legal persons in the case of a No-Deal Brexit. Following the referendum, scholars and politicians have speculated over the Principle’s applicability on EU rights. Some claim that the Principle can be used to protect EU rights while others considers it unreasonable. This thesis

LUNDS UNIVERSITET EKONOMI­ HOGSKOLAN BESLUT 2024-01-12 1 Dnr P 2024/383 Kansli EHL Rektor Lonesattninq for doktorander vid Ekonomihogskolan 2023-04-17 slot Lunds universitet ett lokalt kollektivavtal med personalorganisationerna om lonesattning for doktorander. Enligt detta avtal ( dnr STYR 2023/1007) beslutar respektive fakultet om indelning av forskarutbildningen i tvii eller flera etapper och h

https://www.lusem.lu.se/internal/sites/lusem.lu.se.internal/files/2024-02/L%C3%B6nes%C3%A4ttning%20f%C3%B6r%20doktorander%20vid%20Ekonomih%C3%B6gskolan%20240112.pdf - 2026-07-16