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OBJECTIVES. The aim of this study was to evaluate whether a resuscitation strategy based on administration of 40% oxygen influences mortality rates and rates of improvement in 5-minute Apgar scores, compared with a strategy based on 100% oxygen administration. METHODS. A population-based study evaluated data from 4 Swedish perinatal level III centers during the period of 1998 to 2003. During this

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Overproduction of membrane proteins can be a cumbersome task, particularly if high yields are desirable. NADH:quinone oxidoreductase (complex I) contains several very large membrane-spanning protein subunits that hitherto have been impossible to express individually in any appreciable amounts in Escherichia coli. The polypeptides contain no prosthetic groups and are poorly antigenic, making optimi

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Background: Accurate measurement of von Willebrand factor (VWF) is a critical requirement for the diagnosis of von Willebrand disease (VWD). Aim of the study: To evaluate the diagnostic efficiency of a rapid quantitative test for the measurement of VWF antigen (VWF:Ag) in type 1 VWD. Patients and methods: VWF: Ag was measured with an ELISA in a robotic instrument, as a reference method, and with a

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Purpose To explore the effect of high-dose ifosfamide in first-line treatment for patients <= 40 years of age with nonmetastatic osteosarcoma of the extremity. Patients and Methods From March 1997 to September 2000, 182 patients were evaluated. Primary treatment consisted of two blocks of high-dose ifosfamide (15 g/m(2)), methotrexate (12 g/m(2)), cisplatin (120 mg/m(2)), and doxorubicin (75 mg/m(

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Tapasin is a subunit of the transporter associated with antigen processing (TAP). It associates with the major histocompatibility complex (MHC) class I. We show that tapasin interacts with beta- and gamma-subunits of COPI coatomer. COPI retrieves membrane proteins from the Golgi network back to the endoplasmic reticulum (ER). The COPI subunit-associated tapasin also interacts with MHC class I mole

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The formation name Almelund Shale is proposed for a lithostratigraphically defined unit to replace the outdated chronostratigraphical designations Upper Didymograptus Shale and Dicellograptus Shale in the Middle and lowermost Upper Ordovician succession in Scania. The Almelund Shale is a lithologically uniform unit of dark-grey to black shales with rare carbonate interbeds between the Komstad Lime

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Background: Practices regarding hospitalisation of children at diagnosis of type 1 diabetes vary both within countries and internationally, and high-quality evidence of best practice is scarce. The objective of this study was to close some of the gaps in evidence by comparing two alternative regimens for children diagnosed with type 1 diabetes: hospital-based care and hospital-based home care (HBH

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Background: Many patients with aggressive B-cell lymphomas and high clinical risk score still die of lymphoma after conventional R-CHOP chemoimmunotherapy. We hypothesized that intensified chemoimmunotherapy including systemic central nervous system (CNS) prophylaxis improves outcome and reduces the incidence of CNS-related events. Patients and methods: Inclusion criteria were age 18-65 years, pri

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Syftet med denna uppsats är att visa hur staden Lagos har vuxit i storlek och ökat i befolkning mellan åren 1990-2008. Jämförelser över staden för åren 1990, 1999 och 2008 har gjorts så att huvudragen i stadens tillväxt har kunnat visas och analyseras. Baserat på hur staden har vuxit och förändrats under dessa år så har även tre stycken framtidsmodeller för hur Lagos kan tänkas se ut år 2020 produThe aim of this thesis is to show how the city of Lagos has grown in size and population between the years 1990-2008. Comparisons over the city for the years 1990, 1999 and 2008 have been made so that the main characteristics of the city’s growth can be shown and analyzed. Based on this expansion future prospects for the city has been provided through producing three different scenarios on how Lag

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A recent body of empirical studies has given us a reason to expect that an influx of low-skilled workers can increase high skilled female market labour supply. Most of these studies, however, have focused on developed countries and on investigating the impact as it pertains to immigration. Believing that this same effect might hold in the case of internal migration, in this study, I employ a shift-s

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This thesis aims to explore the role a private network of investors can play when addressing and investing in the Sustainable Development Goals. The network explored is the Sida facilitated network Swedish Investors for Sustainable Development. The network was created in 2016 and has since worked to increase the knowledge among the members regarding how they should invest more efficiently in the S

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En reformerad arbetsrätt trädde i kraft den 30 juni 2022, men började gälla först den 1 oktober. Det innebar främst ändringar i LAS, men det tillkom även en ny bestämmelse i uthyrningslagen. Syftet med dessa förändringar i lagstiftningen är att både öka flexibiliteten och rörligheten på arbetsmarknaden, samtidigt som det ska skapa en större trygghet och förutsägbarhet för både arbetsgivare och arbOn June 30, 2022, a reformed labor law came into effect, but it began to apply on October 1. This mainly involved changes to the Employment Protection Act, but also introduced a new provision in the Temporary Agency Work Act. The purpose of these changes in the legislation is to increase both flexibility and mobility in the labor market, while also creating greater security and predictability for

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A growing world population confronts humanity and the planet with several challenges due to its increased demand for food, space and energy, implying changes in land use. While agriculture currently provides enough food, it is destroying biodiversity and hence aggravates the planet ́s vulnerability to climate change. A paradigm shift might therefore be needed. Applying a political ecology lens, co

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Do genetic risk profiles for drug use disorder (DUD), major depression (MD), and attention-deficit hyperactivity disorder (ADHD) differ substantially as a function of sex, age at onset (AAO), recurrence, mode of ascertainment, and treatment? Methods Family genetic risk scores (FGRS) for MD, anxiety disorders, bipolar disorder, schizophrenia, alcohol use disorder, DUD, ADHD, and autism-spectrum dis

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It is frustrating for every reasonable human being to observe scenes of exploitation around the world in respect of children, because of their either naivety or vulnerability. It is unacceptable that still in the 21st century, children do not benefit from the protection, attention and love they deserve. An estimated 300 million children worldwide are subject to violence, exploitation and abuse inc

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Intellectual property is a very important type of asset in today’s business world. Since business in the Western World grows increasingly based and dependent on know-how and technological development, intangible assets such as trademarks, copyrights and patents plausibly represent greater economic value to economic actors here than other, physical, assets do. Although it is comparatively unknown