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Atrial fibrillation (AF), the most common atria[ arrhythmia, has a complex aetiology and causes relevant morbidity and mortality due to different mechanisms, including but not limited to stroke, heart failure, and tachy- or bradyarrhythmia. Current therapeutic options (rate control, rhythm control, antithrombotic therapy, 'upstream therapy') only prevent a part of this burden of disease. New treat

Background: Pre-hospital electrocardiogram (ECG) transmission to an expert for interpretation and triage reduces time to acute percutaneous coronary intervention (PCI) in patients with ST elevation Myocardial Infarction (STEMI). In order to detect all STEMI patients, the ECG should be transmitted in all cases of suspected acute cardiac ischemia. The aim of this study was to examine the ability of

Objectives: Within the European Prospective Investigation into Cancer and Nutrition (EPIC) study, the performance of 24-h dietary recall (24-HDR) measurements as reference measurements in a linear regression calibration model is evaluated critically at the individual (within-centre) and aggregate (between-centre) levels by using unbiased estimates of urinary measurements of nitrogen and potassium

Sedan 2004, när förordning 1/2003 trädde ikraft, har kommissionen givits en möjlighet att ersätta sitt förfarande för överträdelsebeslut inom tillämpningen av konkurrensrätt, med ett förenklat förfarande där specifika åtaganden görs bindande gentemot företag. Den huvudsakliga skillnaden ligger i att istället för att behöva genomföra en grundlig utredning gällande ett eller flera företags agerandenAs of 2004, with the entry into force of Regulation 1/2003, the Commission has been granted a possibility to substitute its infringement procedure in competition law enforcement, for a simplified commitment procedure. The major difference lies in that instead of having to conduct a thorough investigation into the behaviour of one or more undertakings, and follow this investigation with a finding o

The objectives of this thesis are to find a common ground for business and environmental interests and to evaluate the potential of Environmental Management Systems (EMSs) as transition tools to lead towards a greener economic paradigm. For these purposes it was assessed, which implications EMSs have for the competitiveness of small and medium sized enterprises (SMEs) within the first three years

The modern medical treatment of HIV with antiretroviral therapy (ART) has drastically reduced the morbidity and mortality in patients infected with this virus. ART has also been shown to reduce the transmission risk from individual patients as well as the spread of the infection at the population level. This position statement from the Public Health Agency of Sweden and the Swedish Reference Group

A search has been performed for the experimental signature of an isolated photon with high transverse momentum, at least one jet identified as originating from a bottom quark, and high missing transverse momentum. Such a final state may originate from supersymmetric models with gauge-mediated supersymmetry breaking in events in which one of a pair of higgsino-like neutralinos decays into a photon

Popular Abstract in Swedish Inom forskningsområdet biogeokemi studerar man hur naturens olika grundämnen, såsom kol, kväve, fosfor och kisel ändrar form och transporteras genom landskapet för att via bäckar och vattendrag till slut nå havet. Tillsammans beskriver dessa olika processer, som sker på olika tidsskalor, från sekunder till flera miljoner år, ett grundämnes kretslopp (eller biogeokemiskaSilicon is the next most abundant element in the Earth’s crust and its biogeochemical cycle is linked with that of carbon. Further, silicon is a beneficial nutrient for plants in terrestrial ecosystems and a key nutrient for diatoms in aquatic ecosystems. During the last decade the important role of terrestrial vegetation in controlling Si fluxes downstream aquatic environments, via incorporation

The formation of industry standards for environmental issues and corporate social responsibility is gaining acceptance but the number of successfully implemented programs are few. On an individual level companies have for some time applied company standards or codes of conduct. But on a collective level cooperation seems much more difficult. Although from an economic point of view there are clear

Syfte: Syftet med denna uppsats är att undersöka hur företag inom den industriella sektorn organiserar sig för övergången från att sälja individuella produkter till att sälja integrerade lösningar. Detta exemplifieras genom bl.a. Windahl och Lakemond (2006) liksom Davies et al. (2007) som anser att det finns begränsat med forskning angående utmaningarna som är förknippande med att produkter och tj

Våra jordar är basen för en hållbar matproduktion. Vi har tagit jorden och jordarna för självklara men jordens hälsa är en garanti för framtiden. Jorden vi trampar på är av största vikt för allt levande på land. Med tanke på den alarmerande hastighet med vilken världens jordar håller på att förstöras är det viktigt att fästa uppmärksamheten på jord som en värdefull resurs som måste bevaras och utn

OBJECTIVE To investigate real-world costs of continuous insulin pump therapy compared with multiple daily injection (MDI) therapy for type 1 diabetes. RESEARCH DESIGN AND METHODS Individuals with type 1 diabetes and pump therapy in the Swedish National Diabetes Register (NDR) since 2002 were eligible. Control subjects on MDI were matched 2:

The development of multigene classifiers for cancer prognosis, treatment prediction, molecular subtypes or clinicopathological groups has been a cornerstone in transcriptomic analyses of human malignancies for nearly two decades. However, many reported classifiers are critically limited by different preprocessing needs like normalization and data centering. In response, a new breed of classifiers,

BACKGROUND: At present, selected patients with resectable colorectal peritoneal metastases (CRC-PM) are increasingly treated with a combination therapy of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). The aim of this study was to investigate the current worldwide practice.METHODS: HIPEC experts from 19 countries were invited through the Peritoneal Surface Oncol

This paper reports on a search for electroweak diboson (WW/WZ/ZZ) production in association with a high-mass dijet system, using data from proton-proton collisions at a center-of-mass energy of s=13 TeV. The data, corresponding to an integrated luminosity of 35.5 fb-1, were recorded with the ATLAS detector in 2015 and 2016 at the Large Hadron Collider. The search is performed in final states in wh

BACKGROUND: The effect of a treatment that includes frequent changes of the body position for infants with bronchiolitis has not been evaluated, although it is often used in Swedish hospitals. Because of this, a randomised control trial (RCT) has begun with the aim to evaluate this treatment, comparing the effect of an individualised physiotherapy intervention, a non-individualised intervention, a

Background: Patients have an estimated mortality of 15–20% within the first year following myocardial infarction and one in four patients who survive myocardial infarction will develop heart failure, severely reducing quality of life and increasing the risk of long-term mortality. We aimed to establish the accuracy of an artificial neural network (ANN) algorithm in predicting 1-year mortality and