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Red blood cells may regulate tissue circulation and O-2 delivery by releasing the vasodilator ATP in response to hypoxia. When released extracellularly, ATP is rapidly degraded to ADP in the circulation by ectonucleotidases. In this study, we show that ADP acting on P2Y(13) receptors on red blood cells serves as a negative feedback pathway for the inhibition of ATP release. mRNA of the ADP recepto

Moraxella catarrhalis ubiquitous surface proteins A1 and A2 (UspA1/A2) interfere with the classical pathway of the complement system by binding C4b-binding protein. In this study we demonstrate that M. catarrhalis UspA1 and A2 noncovalently and in a dose-dependent manner bind both the third component of complement (C3) from EDTA-treated serum and methylamine-treated C3. In contrast, related Moraxe

When a swift heavy ion (SHI) penetrates amorphous SiO2, a core/shell (C/S) ion track is formed, which consists of a lower-density core and a higher-density shell. According to the conventional inelastic thermal spike (iTS) model represented by a pair of coupled heat equations, the C/S tracks are believed to form via "vaporization" and melting of the SiO2 induced by SHI (V-M model). However, the mo

BackgroundFor advanced pancreatic cancer, pulmonary metastases (PM) have been considered favorable factors compared to metastases of other sites, but it remains unknown whether the prognosis of patients with synchronous liver and lung metastases is better than that of non-PM.MethodsData was derived from a two-decade cohort and included 932 cases of pancreatic adenocarcinoma with synchronous liver

The ESC diagnostic criteria for infective endocarditis (IE) added spondylodiscitis as minor diagnostic criterion. Of patients with Staphylococcus aureus, streptococcal or Enterococcus faecalis bacteremia, 11 of 1807 episodes were reclassified to definite IE of which nine were not treated as IE. Spondylodiscitis as a minor criterion decreases specificity of the criteria.

LUMES 2018-2020 Thesis Seminar Schedule MAY 2020 2020 LUMES THESIS SCHEDULE – VIA ZOOM CHECK LINK & PASSWORD FOR EACH EXAMINER: CANVAS FRIDAY 22 MAY 2020 MONDAY 25 May 2020 DAY LINK AMANDA WILL SEND OUT ZOOM LINK VIA CANVAS ON FRIDAY 22 MAY 2020 MONDAY Venue Examiner Respondent Thesis Title Discussants Supervisor 8.00-8.45 ZOOM Anne Jerneck Hiroka Ka Ho TAIWAN Will Plastic Ever Go Away? An analysi

https://www.lumes.lu.se/sites/lumes.lu.se/files/2020_lumes_thesis_schedule_25-26_may_version_20_may.pdf - 2026-07-17

This study examines the management of used mobile phones in the United Kingdom between 2005 and 2008. It shows that the replacement cycle for mobile phones got shorter during the period due to heavy handset subsidies given by mobile network operators. The planned obsolescence presented a business opportunity for the exports of used phones to developing countries. However, the collection for re-use

We studied clinical performance of serum TRACP 5b and other bone turnover markers, including S-CTX, U-DPD, S-PINP, S-BALP, and S-OC, for monitoring alendronate treatment. TRACP 5b had higher clinical sensitivity, area under the ROC curve, and signal-to-noise ratio than the other markers. INTRODUCTION: The purpose of this study was to compare the clinical performance of serum TRACP 5b (S-TRACP5b) w

The importance of tyrosine residues in ligand-mediated endocytosis of the platelet-derived growth factor beta-receptor was analyzed using a series of tyrosine residue-mutated beta-receptors, which together cover all of the tyrosine residues in the juxtamembrane segment, the kinase insert, and the carboxyl-terminal tail; also certain of the tyrosine residues within the first and second parts of the

Background Lower-respiratory-tract infection is one of the most common acute illnesses managed in primary care. Few placebo-controlled studies of antibiotics have been done, and overall effectiveness (particularly in subgroups such as older people) is debated. We aimed to compare the benefits and harms of amoxicillin for acute lower-respiratory-tract infection with those of placebo both overall an

Compression anastomotic ring-locking procedure (CARP) is a novel procedure for creating colonic anastomoses. The surgical procedure allows perioperative quantification of the compression pressure between the intestinal ends within the anastomosis and postoperative monitoring of the anastomotic integrity. We have recently shown that CARP is a safe and effective method for colonic anastomoses in pig

Background Low energy availability (EA) in female athletes with or without an eating disorder (ED) increases the risk of oligomenorrhoea/functional hypothalamic amenorrhoea and impaired bone health, a syndrome called the female athlete triad (Triad). There are validated psychometric instruments developed to detect disordered eating behaviour (DE), but no validated screening tool to detect persiste

Although fear of falling (FOF) is common in people with Parkinson's disease (PD), there is a lack of research investigating potential predictors of FOF. This study explored the impact of motor, nonmotor, and demographic factors as well as complications of drug therapy on FOF among people with PD. Postal survey data (including the Falls Efficacy Scale, FES) from 154 nondemented people with PD were

This study explored the role of secreted fibroblast-derived factors in prostate cancer growth. Analyses of matched normal and tumor tissue revealed up-regulation of CXCL14 in cancer-associated fibroblasts of a majority of prostate cancer. Fibroblasts overexpressing CXCL14 promoted the growth of prostate cancer xenografts, and increased tumor angiogenesis and macrophage infiltration. Mechanistic st

https://www.lunduniversity.lu.se/sites/www.lunduniversity.lu.se/files/26bafac79aaf44b128c9b9247e10b78befdc1265_BIOR88_2026_kursanalys.pdf - 2026-07-17

Period 1: Sep. 1 - Oct. 31 Period 2: Nov. 3 - Jan. 16 Period 1: Jan. 19 - Mar. 20 Period 2: Mar. 23 - Jun. 5 Microbiology BIOR18, 15 cr Immunology BIOR85, 15 cr Immunology & Infection Biology BIOR88, 15 cr Antibiotics - Biology & Chemistry BIOR56, 7.5 cr, a Molecular Genetics of Eukaryotes BIOR95, 15 cr Molecular Microbiology BIOR63, 15 cr Molecular Biotechnology & Methods BIOR94, 15 cr Pharmacolo

https://www.biologyeducation.lu.se/sites/biologyeducation.lu.se/files/2025-06/Course%20planning%20list%20for%20Molecular%20Biology%20students%2025-26_0.pdf - 2026-07-17