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Introduction: Obesity is a chronic, progressive, and recurring disease that contributes significantly to multimorbidity across Europe. Despite the publication of numerous clinical practice guidelines (CPGs) for obesity, many chronic disease guidelines for obesity related diseases such as diabetes, MASLD, heart disease, obstructive sleep apnea do not integrate contemporary understandings of obesity
Accessible design enables participation in the digital society for everyone. However, cognitive accessibility is not well established within the field of web design. The International Classification of Functioning, Disability and Health (ICF) provides a descriptive framework that relates health conditions to functioning and participation. ICF Core Sets are purposefully tailored shortlists of ICF c
Background: Rare disease clinical trials are notorious for complexities that frequently result in study-start delays. However, there is limited knowledge about how participants and researchers perceive these delays and what factors shape their experiences. A clinical trial in the rare, progressive disorder Pantothenate Kinase-Associated Neurodegeneration—the PKAN trial—encountered an unexpected de
STUDY QUESTION What are the perspectives of oocyte and sperm donors 14-17 years post-donation on the release of their identity and potential contact with donor-conceived offspring (DCO)? SUMMARY ANSWER Most oocyte and sperm donors wanted to be notified about future releases of their identity and were positive towards contact with DCO, but more than half expressed a need for support in relation to
Since 2002, Swedish higher education institutions have been mandated by the Higher Education Act to actively promote widening participation. However, there is no national definition of widening participation, leaving each institution to define its own objectives. This article investigates how teachers at Lund University in Sweden understand and implement widening participation, examining their perSince 2002, Swedish higher education institutions have been mandated by the Higher Education Act to actively promote widening participation. However, there is no national definition of widening participation, leaving each institution to define its own objectives. This article investigates how teachers at Lund University in Sweden understand and implement widening participation, examining their per
The writings of the Austrian novelist and essayist Robert Musil provide sociology with vital problems and reflections. Indeed, Musil, not least in the novel The Man without qualities, introduces discussions that extend conventional and recurrent understanding of modernity – sociology’s general object of analysis. The paper focuses on three major sets of questions in Musil’s work: 1) the shapelessnThe writings of the Austrian novelist and essayist Robert Musil provide sociologywith vital problems and reflections. Indeed, Musil, not least in the novel The Manwithout qualities, introduces discussions that extend conventional and recurrentunderstanding of modernity – sociology’s general object of analysis. The paperfocuses on three major sets of questions in Musil’s work: 1) the shapelessness
Background: Optimal long-term follow-up (LTFU) care for survivors of childhood, adolescent and young adult (CAYA) cancer can improve or maintain their quality of life by prevention and early treatment of late effects. However, optimal LTFU care is not provided to all CAYA cancer survivors. This systematic review sought to identify associated barriers, facilitators and other factors of LTFU care fo
Urbanization in coastal megacities leads to trade-offs between development and ecology, degrading carbon sinks and disrupting spatial-functional balance. Current models often fail to integrate land use, carbon dynamics, and ecological zoning. This study created a system that brings together Patch-generating Land Use Simulation (PLUS), Integrated Valuation of Ecosystem Services and Trade-offs (InVE
Violent offenders are a heterogeneous group where criminogenic needs often are substantial and violent behaviors persistent. Risk, Need, and Responsivity (RNR)-based treatment has shown effect on reducing the risk for recidivism in violent crime, but the development of novel treatments is crucial in making the change process more effective. Virtual Reality (VR) technology may be a tool to improve
Monitoring toxic elements has a long tradition in Slovenia due to historical mining. More recently, attention has shifted to essential elements, since both deficiencies and excesses can harm health. Regular monitoring of (non-)essential elements supports risk assessment and policymaking. While urine and blood are common biomonitoring matrices, hair offers a non-invasive alternative that reflects e
Background Bacterial vaginosis (BV) is the most common vaginal infection among women of reproductive age worldwide, caused by dysbiosis of the vaginal microbiome. Despite its prevalence, the underlying molecular mechanisms remain poorly understood, making diagnosis and treatment challenging. Although antibiotics are the standard therapy, recurrence rates are high, up to 50% within 1 year, and repe
The exponential rise in atmospheric CO₂ driven by human activities is accelerating climate change and causing ocean acidification (OA). While the effects of elevated CO₂ on a wide range of marine species have been well documented, the implications of OA for bivalve aquaculture have received comparatively little attention. Using a multi-level meta-analytical approach, we evaluated the impacts of tw
The laminar burning velocity (SL) of methane (CH4), the primary constituent of natural gas, is a key combustion property essential for validating combustion kinetic models. The present study focuses on the CH4 SL at the very rich side of flames, where the available experimental data are scarce with highly dispersed measurement conditions, and data projection was carried out to overcome the difficu
Daylight is crucial for the well-being of individuals in indoor environments, providing numerous physiological and psychological benefits. Achieving satisfactory daylight levels can be particularly challenging during adaptive reuse of existing buildings for new purposes. This study determined the feasibility of adapting an office for residential use by assessing interior daylight availability and
Urban planning is increasingly embedded in a neoliberal paradigm, resulting in decentralization and deregulation of planning practice. This affects how compact cities are materialized. However, few studies of the effects of neoliberal planning for density consider the resulting geographies of green space. To address this research gap, this paper explores how the idea of green space is being reconf
The moult of Barred Warblers Sylvia nisoria was studied during three winter seasons in southeastern Kenya at a southward passage site (Ngulia) and a wintering site (Mtito Andei). Most Barred Warblers migrating through Ngulia in November had yet to commence winter moult. These birds probably moulted subsequently in winter in northern Tanzania. In December, birds were found in heavy moult at Mtito A
This article presents a critical appraisal of the European Union’s (EU) policy process that delivered the Critical Raw Materials Act, 2023–2024. We combine Marxist-Gramscian perspectives on regional blocs and social movement theory on transnational contestation to study a framing contest at two points in the policy process. First, we examined environmental justice frames in technical campaigns to
PURPOSE: The predictive value of excision repair cross-complementation group 1 (ERCC1) gene for survival and response to platinum-based chemotherapy in gastric cancer (GC) remains controversial. We performed a meta-analysis to clarify the precise estimation of the prognostic and predictive effect of ERCC1.METHODS: A systematic literature search was conducted using PubMed, ScienceDirect, Wiley and
Introduction: Patients with substantial comorbidity burden are underrepresented in clinical trials on endovascular thrombectomy (EVT), despite being common in clinical routine care. Therefore, analysis of observational data is needed to evaluate how increasing comorbidity burden affects procedural success rate, complication rate, and clinical outcome following EVT. Patients and methods: We conduct
Title: Women experiencing the second stage of labour for the first time: a qualitative free-text analysis within the Oneplus trial. Background: The second stage of labour is the time from full cervical dilation to the birth of the baby. The risks to the woman and the baby are increased during this stage, leading to intensified midwifery care. A positive birth experience is a significant goal of in
