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Although drug abuse (DA) is strongly familial, with important genetic influences, we need to know more about the role of rearing environment in the risk for DA. To address this question, we utilized a high-risk adopted and non-adopted co-sibling control design.

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Satisfaction with the outcome of treatment is a widely used outcome measure but information about the determinants of patient satisfaction after surgery for central spinal stenosis (CSS) are lacking. The aim of the study was to analyze determinants of patient satisfaction 1 year after surgery for CSS without degenerative spondylolisthesis (DS).

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OBJECTIVES: The soluble epoxide hydrolase (gene name EPHX2) is responsible for metabolism of 8,9 11,12 and 14,15-epoxyeicosatrienoic acids, vasodilator and anti-inflammatory substances. There are several functional polymorphisms in the EPHX2 gene: two of them, the K55R and R287Q, showing an altered metabolic activity in vitro, were associated with coronary heart disease and ischemic stroke in prev

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The purpose of this study was to evaluate an abdominal CT protocol in which radiation dose was reduced and IV contrast dose increased for young patients and radiation dose was increased and IV medium dose decreased for elderly patients. The hypothesis was that these adjustments would result in constant image quality and a reduction in age-specific risk.

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The αE integrin chain CD103 identifies a subset of migratory dendritic cells (DCs) in the gut, lung, and skin. To gain further understanding of the function of CD103(+) DCs in regulating adaptive immunity in vivo, we coupled ovalbumin (OVA) to the CD103 antibody M290 (M290.OVA). Intraperitoneal injection of M290.OVA induced OVA-specific CD8(+) and CD4(+) T-cell proliferation in lymph nodes (LNs) o

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OBJECTIVE : To identify predictors of later study withdrawal among participants active in The Environmental Determinants of Diabetes in the Young (TEDDY) for 1 year. METHODS : Multiple logistic regression was used to discriminate 3,042 children active in TEDDY for the first 3 years from 432 children who withdrew in Years 2 or 3. Predictor variables were tested in blocks-demographic, maternal lifes

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Climate-related security risks (CRSR) have risen on the foreign policy agenda of the European Union (EU). As climate change accelerates, its impacts exacerbate existing social, economic, and environmental challenges within and between communities and increase the likelihood of states experiencing humanitarian crises and conflict. These so-called climate-related security risks (CRSR), or climate-se

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The relevance of M&E insights being utilized for reporting, contra planning purposes, for predicting level of outcome implementation have been neglected in previous literature. However, this study can show that when measurements and evaluations is used for future planning of communication activities, level of outcome implementation increase largely. This study can also predict the level of wh

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For many years, indigeneity has been conceptualized as rural, making Indigenous communities and people in cities invisible globally. For the Sámi people, Europe’s only indigenous people, security is mainly understood as physical-centering extraction and environmental degradation. Focusing on the urban Sámi community in Umeå in Sweden, cultural and political belonging in the city arises as vital in

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Buildings are a are a major consumer of energy in urban areas. The use of solar energy in buildings can help reduce CO2 emitting energy consumption in these urban areas. One way to use solar energy is through passive solar energy systems. Passive solar energy systems allow a building to use daylight as an energy source. The use of daylight as passive solar energy in Sweden could reduce the energy

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The release of anthropogenic greenhouse gases (GHGs) has substantially increased the global mean surface air temperature. Increases in global mean surface air temperature will lead to warmer and drier conditions, promoting more frequent, long-lasting, intense forest wildfires. The usage of remote sensing (RS) can aid in quantifying forest characteristics and large-scale changes in forest ecosystem

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Incorporating a multi-year grass ley into an arable crop rotation can increase soil organic carbon stocks, reduce carbon emissions and provide feedstock for biogas. This thesis set out to study how a policy promoting agricultural biomass for biogas impacts GHG emissions and carbon sequestration on a regional level over a temporal scale of 20 years. This was done in the specific case of policy prom

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Human-induced climate change has emerged as one of the greatest sustainability challenges of our time, with significant risks for human health, livelihoods and security. However, technological solutions to phase out the use of fossil fuels in industrialized countries are politically contested. Their adoption depends on disrupting the institutions and behaviours that perpetuate the dependence on fo

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The goal of this thesis work is to implement a convolutional neural network on an FPGA device with the capability of recognising human sign language. The set of gestures that the neural network can identify has been taken from the Swedish sign language, and it consists of the signs used for representing the letters of the Swedish alphabet (a.k.a. fingerspelling). The motivation driving this projec

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This thesis evaluates the performance of an EPR programme for post-consumer PET waste management by PET recycling company (PETCO) in South Africa. It analyses waste management policies of South Africa that are relevant to EPR. Using a set of evaluative tools, the thesis reveals areas for improvement in the EPR scheme. It also identifies areas in informal sector interventions where EPR can contribu

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Today, Swedish police authorities nationwide collect data of traffic accidents. The information is stored in a national database managed by the Swedish Transport Agency and is an important resource in the process of analysing and improving road safety. Literature studies in this thesis, together with earlier work by the author have suggested that the data collection process is in need of an upda

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Nature-based Solutions (NBS) are one of the approaches to the regeneration of urban areas. These solutions are copied from, inspired by, or supported by nature. The solutions, ideally, result in multiple benefits to the society and environment. The examples of NBS measures for stormwater management are, including but not limited to, natural swale, retention ponds, and green roofs. Such measures ha

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This thesis examines whether the general principle of the right to good, as enshrined in Article 41 of the Charter of Fundamental Rights of the European Union (CFR), can be considered an independent justiciable right for individuals. The analysis focuses in particular on recent concerns about rule of law backsliding in certain Member States and the resulting limitations on effective judicial prote

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Concerto for Double Bass and Orchestra by Eduard Tubin is considered to be one of the most challenging pieces of the double bass repertoire as it is known to be a physically demanding work. It was written for double bass player Ludvig Juht who was a physically big built man and welcomed the technical challenges. This thesis aims to analyze these challenges of the piece for a player with smaller ph

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With his notion of original affirmation, Paul Ricoeur wishes to reinstate the primacy of being over nothingness, joy over anguish, and affirmation over negation. Having adopted the term from Jean Nabert, he draws from the tradition of French reflective philosophy to formulate his conception of the originally affirmative nature of existence. Ricoeur argues that positive values can be found in and t