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Chemokines are important in the development and progression of tumors. We investigated the expression of CXCL14 and CXCL16 in colon cancer. Expression of mRNA was assessed in primary tumors and lymph nodes and CXCL16 mRNA levels were correlated to patient’s survival. Protein expression was investigated by two-color immunofluorescence and immunomorphometry. CXCL14 and CXCL16 mRNA levels and protein
OBJECTIVES:: Vitamin K deficiency (VKD) may cause life-threatening haemorrhages, especially in breast-fed infants with unrecognised cholestasis. Interestingly, hypoallergenic formulas appear overrepresented in reported cases of VKD bleeding (VKDB) in formula-fed infants. We therefore assessed whether the risk of VKD in formula-fed infants with cholestasis is associated with hypoallergenic formulas
Purpose: The FANCM c.5101C>T nonsense mutation was previously found to associate with breast cancer in the Finnish population, especially among triple-negative cases. Here, we studied the prevalence of three other FANCM variants: c.5791C>T, which has been reported to predispose to familial breast cancer, and the c.4025_4026delCT and c.5293dupA variants recently identified in Finnish cancer patient
An arabinose specific xylanase from glycoside hydrolase family 5 (GH5) was used to hydrolyse wheat and rye arabinoxylan, and the product profile showed that it produced arabinose substituted oligosaccharides (AXOS) having 2-10 xylose residues in the main chain but no unsubstituted xylooligosaccharides (XOS). Molecular modelling showed that the active site has an open structure and that the hydroxy
Ozone oxidation of organic micropollutants in biologically treated wastewater was investigated in pilot-scale after a high- and a low loaded activated sludge process. Higher ozone doses were required to remove organic micropollutants in the effluent wastewater from the high loaded activated sludge process. Further comparison of the micropollutant removal was based on normalized ozone doses, expres
Aims: The NAB2-STAT6 fusion was recently identified as a consistent finding in solitary fibrous tumour (SFT), resulting in nuclear expression of the C-terminal part of STAT6. Gene expression studies of SFT revealed high expression of the GRIA2 gene. The aim of this study was to examine GRIA2 expression in SFTs and other soft tissue tumours to evaluate its diagnostic utility. Methods and results: I
Schema Riskanalys inom natur, miljö och hälsa MVEC12 15 högskolepoäng, HT 2014 PRELIMINÄRT version 20140825 VECKA DATUM DAG TID TITEL Form Lärare Läs SAL HUS BLOCK V. 36 01-sep må 13.00-14 Upprop, Kursintroduktion S MH Receptorn Biologihuset INTRODUKTION KURS 02-sep ti 10-12 Risker med nanopartiklar F MHE+MOK Ängen Ekologihuset HÄLSA 03-sep on 9-12 Introduktion om biomarkörer och hälsostudier F CL
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mvec12_schema.pdf - 2026-07-10
MVEN03_Preliminar_Planering_Schema_HT_2020_v9.xlsx MILJÖVETENSKAP Preliminär planering/schema 200826 Kurs: MVEN03 ‐ Miljövetenskap: Analys och metodik, 15 hp HT 2020 Kursansvarig: Nina Reistad NR nina.reistad@fysik.lth.se Lärare: Charlotta Turner CT charlotta.turner@chem.lu.se Per Erik Isberg PEI per‐erik.isberg@stat.lu.se Pål Axel Olsson PAO pal_axel.olsson@biol.lu.se Martijn van Praagh MVP m
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mven03_preliminar_planering_schema_ht_2020_v9.pdf - 2026-07-10
This paper reports on research on the engagement of ISO 14001 certified companies in environmental supply chain management, the drivers and barriers that influence their involvement, and how these forces correspond to the internal environmental management activities. In parallel, the issues of internal capabilities of companies, crucial for companies to respond to such driving forces, are highligh
When constructivism gives up reality as a way of accounting for representations it looses a powerful tool of explanation. Why do we have the representations we have? How are they interrelated? This article attempts to investigate what possible means a constructivistic theory has to maintain the distinction between representations and experience, between memory and imagination, and between correct
Altered renal function is an essential component of the pathophysiological process in preeclampsia. The kidneys play a significant part in the turnover of most low molecular weight substances such as creatinine, urate and cystatin C. The present work was undertaken to investigate if the serum levels of these components are altered in characteristic ways in preeclampsia, and can be used to assist i
Abstract Introduction Carpal tunnel syndrome (CTS) is thought to be due to compression of the median nerve in the carpal tunnel. It is known that carpal tunnel pressures are elevated in wrist postures of flexion and extension and in those patients with CTS. Classic symptoms of CTS include night waking with pain, tingling, and numbness. These classic symptoms stimulated our interest in the relation
Very-low-density lipoprotein (VLDL) from 10 hemodialysis patients and 10 healthy controls was studied with respect to the substrate characteristics for bovine milk lipoprotein lipase (LPL). Compared with the control subjects, the hemodialysis patients had significantly higher serum triglyceride and apolipoprotein B-associated apolipoprotein CIII concentrations (1.03 +/- 0.31 v 1.98 +/- 0.86 mmol/L
OBJECTIVE: The validity of the Ross operation as freestanding root replacement in adult patients with bicuspid aortic valve disease has lately been questioned. We have analyzed retrospectively our results in 23 adult patients (19 males) operated for bicuspid aortic valve disease ad modum "Ross" employing a freestanding root replacement technique. DESIGN: In 9 patients the dominant aortic valve les
Background/Aims: This study was designed to examine the role of selectins and CD18 in leukocyte recruitment in hepatic injury induced by tumor necrosis factor-alpha (TNF-alpha) and galactosamine (Gal) in vivo.Methods: Intravital fluorescence microscopy of the hepatic microcirculation was used to quantify leukocyte-endothelium interactions provoked by 24 h of systemic TNF-alpha/Gal challenge in rat
In the present study, the involvement of cytochrome P450 enzyme( s) in the primary metabolism of laquinimod, a new orally active immunomodulator, has been investigated in human liver microsomes. Hydroxylated and dealkylated metabolites were formed. The metabolite formation exhibited single enzyme Michaelis-Menten kinetics with apparent K-M in the range of 0.09 to 1.9 mM and V-max from 22 to 120 pm
Background. Previous studies have shown high rates of psychosis among Afro-Caribbean immigrants to the UK and immigrants to the Netherlands. Rates of schizophrenia-like psychoses (SLP), i.e. schizophrenia or other non-affective psychosis, among the native-born and immigrant populations were assessed in Malm, the city in Sweden with the highest proportion of immigrants.Methods. All adult patients a
