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Biofuels are still too costly to compete in the energy market and it has been suggested that low-value feedstocks could provide an opportunity for the production of low-cost biofuels; however, the lower quality of these feedstocks requires the introduction of a conditioning step in the biorefinery process. The aim of this study was to evaluate whether feedstock savings cover the cost of conditioni
Difficulty in obtaining bone tissue is an obstacle to studying epigenetics to understand gene–environment interactions, and their role in disease pathogenesis. Blood is an obvious alternative and in this proof of principle study, our aim was to systematically investigate whether blood is a viable surrogate for bone. We measured epigenome-wide DNA methylation at 850 K CpG sites in matched trabecula
A green route for the production of 6-carbon polymer building blocks 6-hydroxyhexanoic acid, adipic acid and ϵ-caprolactone from 1,6-hexanediol, a hydrogenation product of biobased 5-hydroxymethylfurfural is reported. Gluconobacter oxydans oxidized 1,6-hexanediol completely to adipic acid, and selectively at pH 6-7 to 6-hydroxyhexanoic acid, which was converted to ϵ-caprolactone by catalytic cycli
Abstract: A popular belief is that the process whereby search engines tailor their search results to individual users, so-called personalization, leads to filter bubbles in the sense of ideologically segregated search results that would tend to reinforce the user’s prior view (filter bubble hypothesis). Since filter bubbles are thought to be detrimental to society, there have been calls for furthe
OBJECTIVE The authors aimed to develop the first clinical grading scale for patients with surgically treated spontaneous supratentorial intracerebral hemorrhage (ICH). METHODS A nationwide multicenter study including 401 ICH patients surgically treated by craniotomy and evacuation of a spontaneous supratentorial ICH was conducted between January 1, 2011, and December 31, 2015. All neurosurgical ce
Smart cyber-physical systems (S-CPSs) are complex engineered systems empowered by cyber-physical computing and equipped with the capability of reasoning, learning, adapting, and evolving. As an outcome of data-driven dynamic computing, reasoning capabilities, and the run-time obtained own knowledge, nonlinear and emergent behavior of S-CPSs whilst in operation is an open issue, not experienced in
Objectives This study aimed to evaluate the image quality of 7 iterative reconstruction (IR) algorithms in comparison to filtered back-projection (FBP) algorithm. Methods An anthropomorphic chest phantom was scanned on 4 computed tomography scanners and reconstructed with FBP and IR algorithms. Image quality of anatomical details - large/medium-sized pulmonary vessels, small pulmonary vessels, tho
Introduction: Post-traumatic stress disorder (PTSD) and substance use disorder frequently co-occur and tend to have their onset during adolescence. Although research has highlighted the importance of treating these disorders in an integrated fashion, there is a dearth of empirically validated integrated treatment options for adolescents with this comorbidity. This paper describes the study protoco
Background: Targeted surveillance of at-risk individuals in families with increased risk of hereditary cancer is an effective prevention strategy if relatives are identified, informed and enrolled in screening programs. Despite the potential benefits, many eligible at-risk relatives remain uninformed of their cancer risk. This study describes the general public's opinion on disclosure of hereditar
Background and purpose — Hallux rigidus (HR) may cause decreased range of motion, joint pain, and gait disturbances. There is a lack of evidence regarding the outcome of different surgical procedures for moderate HR. We report patient-reported outcomes after joint-preserving surgical procedures for moderate HR. Patients and methods — We included 296 patients registered in Swefoot (Swedish national
Context. NGC 2264 is a young cluster whose accretion properties can be investigated in detail by taking advantage of the FLAMES data in the context of the Gaia-ESO Survey. In fact, the analysis of the Hα emission line profile can provide us with information about the accretion and ejection activity of young stars. However, a strong nebular emission that contributes to the Hα emission can alter the
Purpose of Study: To gain Swedish norm value for the Life Satisfaction Index-A (LSI-A) in a population 60–93+ years old stratified for sex and age and to relate these norm values with respect to number of chronic diseases and functional impairment. Materials and Methods: The study population included a random sample of 2656 men (45.7%) and 3159 (54.3%) women from the longitudinal national studies’
BACKGROUND: The area of hospital readmission in older adults within 30 days of discharge is extensively researched but few studies look at the whole process. In this study we investigated risk factors related, not only to patient characteristics prior to and events during initial hospitalisation, but also to the processes of discharge, transition of care and follow-up. We aimed to identify patient
This thesis examines the evolution of Policy Coherence for Development (PCD) in the EU. The overarching purpose is to give an example of ideational causation in the EU, and concretely, to illustrate how a norm can cause changes to policy and to policymaking. It is argued that the PCD concept is essentially a norm, because it provides a guideline for how to prioritize between differing and often co
This is a case study that aims to explain the adoption of the Victims’ Law by investigating the transnational advocacy networks’ work for the rights of the victims of the armed conflict in Colombia. Theories of transnational advocacy networks and opportunity structures are applied in order to understand the long term advocacy work for the victims’ rights, but also to explain their influence on the
The question of the Palestine refugees has been an issue to the United Nations’ General Assembly (UNGA) ever since its creation in 1948, and it has played an immense role in the Israeli-Palestine conflict. Everyone involved wants to find a solution to the problem, but 65 years on, the issue is as complex as it has ever been. The question of which actor have the main human rights responsibility for
Purpose: The purpose of this research is to explore possible cost effective strategies for increasing brand awareness amongst certain stakeholder groups of an acquired, previously well known brand operating in a high tech B2B industry. Methodology: A qualitative, exploratory case study of RUAG Space AB, an acquired company previously holding high brand awareness in Sweden, was conducted. This was
Gaming disorder (GD) is an addictive disorder with health and social impacts recognized by the World Health Organization. Although the GD treatment evidence base appear to favor cognitive behavioral therapy (CBT), knowledge of its common practice elements is limited. This systematic review critically evaluates CBT interventions for GD, encompassing individual, group, and mixed approaches, to ident
