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Lignin is the most abundant aromatic biopolymer on Earth, and its aromatic structure makes it a promising platform for the production of biobased chemicals and other valuable building blocks. The valorization of lignin into chemicals currently presents a challenge, and its facilitation is key in the development of viable lignocellulosic biorefinery processes. This study presents a conceptual desig
Background: It is unclear which radiotherapy technique and dose fractionation scheme is most effective in decreasing the risk of prostate cancer death. Methods: We conducted a population-based cohort study among 15 164 men in the Prostate Cancer database Sweden (version 4.0) treated with primary radical radiotherapy for prostate cancer in Sweden from 1998 to 2016. We calculated hazard ratios with
Apart from microhardness and elastic modulus, the stress-strain relation is another important characteristic that more and more scholars have been trying to extract from nanoindentation. With the development of artificial intelligence and computer technology, a machine learning based method is proposed in this paper to extract stress-strain curve of grey cast iron using sharp nanoindentation. Firs
The aim of this study was to establish creatinine growth curves separately for males and females that can be used to adjust childhood levels of serum creatinine to corresponding adult levels. Linear regression with fractional polynomials of age as independent variable was used to construct creatinine growth curves for a reference cohort (n = 83,157 samples from Belgium and Sweden, age 2–40 years).
Individuals with severe self-harm and experiences of lengthy psychiatric admissions often have complex mental health conditions and are at risk of suicide. In this qualitative study, self-harming individuals with >180 days of psychiatric admission over 12 months shared their experiences of Brief Admission (BA), a standardized crisis-management intervention encouraging self-admission and autonomy.
Fire smoke in a tunnel fire is a key factor causing casualties, thus the critical longitudinal ventilation velocity is a key parameter in tunnel fire safety ventilation design. The correlation of critical longitudinal ventilation velocity for smoke control in a tunnel induced by two nearby fires has rarely been studied experimentally and quantified before, despite the fact that this scenario exist
BACKGROUND: Hospitalized newborn infants may require analgesia and sedation either for the management of procedural pain, during or after surgery, and other painful conditions. The benefits and harms of opioids administered at different doses and routes of administration have been reported in numerous trials and systematic reviews. The use of alpha-2-agonists such as clonidine and dexmedetomidine
Deoxyribonucleoside triphosphates (dNTPs) are vital for the biosynthesis and repair of DNA. Their cellular concentration peaks during the S phase of the cell cycle. In non-proliferating cells, dNTP concentrations are low, making their reliable quantification from tissue samples of heterogeneous cellular composition challenging. Partly because of this, the current knowledge related to the regulatio
The transitions to a low carbon and sustainable society are urgent, but at the current level and pace of action there is a significant risk we will escalate and exceed the goals of the Paris Climate Agreement and fail to achieve the Sustainable Development Goals. By engaging cities, we can build momentum around bottom-up interconnected actions and accelerate societal and technological transitions.
The robust engineering seeks for design of products and processes insensitive to changes in the work environment and to the variation of the components. The robust process has built-in mechanisms to detect potential errors on time, to eliminate them and to initiate all the necessary measures to ensure the same error does not occur again. One-of-a-kind production is characterised by unique products
Purpose: The use of optical surface systems (OSSs) for patient setup verification in external radiation therapy is increasing. To manage potential deformations in a patient’s anatomy, a novel deformable image registration (DIR) tool has been applied in a commercial OSS. In this study we investigate the accuracy of the DIR as compared to rigid image registration (RR). Methods and Materials: The pos
Forestry is raising concern about the outbreaks of European spruce bark beetle, Ips typographus, causing extensive damage to the spruce forest and timber values. Precise monitoring of these beetles is a necessary step towards preventing outbreaks. Current commercial monitoring methods are catch‐based and lack in both temporal and spatial resolution. In this work, light scattering from beetles is c
Whole exome and whole genome sequencing are increasingly being offered to patients in the clinical setting. Yet, the question of whether, and to what extent, unsolicited findings (UF) and/or secondary findings (SF) should be returned to patients remains open and little is known about how diagnostic consent forms address this issue. We systematically identified consent forms for diagnostic genomic
Children's early engagement in design of outdoor spaces can form the basis of later attitudes and responsible action for sustainability. The present study is part of a participatory action research project in an urban multi-ethnic preschool in Sweden, involving children, parents, preschool staff and management with a focus on improving the preschool playground. The methodology involved children ta
This paper provides an answer to the requests that has been made for witness confrontations to become an accurate and reliable tool in the court. This was achieved by the development and testing of the Guilty Face Test (GFT). Facial stimuli was used in a Target Present lineup were the enhanced elicitation of the Even-Related Potential component P300 confirmed recognition of the culprit. The partic
This essay is a presentation of the elegy for cities in Andalusí-Arabic poetry. In this essay, which is a presentation, the reader is presented with three full poems of Andalusi-Arabic Elegy for lost cities, brief analyses of the poems in terms of content and style, background information concerning the poems, short biographies of the poets. Different aspects of the Andalusí-Arabic elegy for citie
The purpose of this study was to investigate three aspects of asexuality. This was achieved through conducting six interviews with self identified asexuals, an observation on a meeting for asexuals, an analysis of what functions the two organisations for asexuals, Nätverket Asexuell and AVEN have, and a content analysis concerning how people talk about a lack of sexual lust on the internet. The co
In spite of the modernization of obstetrics in Tamil Nadu, the rural women still adhere to several traditional beliefs and practices, in regard to childbearing and postpartum. The varieties of non-biomedical practices were used in attempt to ensure a risk-free delivery and the birth of a healthy baby, although the collected data shows that some of them are harmful. To understand why the rural wome
The combination of graphical models with Aalen's additive hazards model, resulting in a model known as dynamical path analysis, permits assessing the effects of different variables on times until an event and decomposing these total effects into direct and indirect effects. This thesis proposes novel bootstrapping methods designed for left-truncated right-censored data, conditional on covariat
