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OBJECTIVE: Prostate cancer cells secrete the unique protease human glandular kallikrein 2 (hK2) that represents a target for proteolytic activation of cytotoxic prodrugs. The objective of this study was to identify hK2-selective peptide substrates that could be coupled to a cytotoxic analogue of thapsigargin, a potent inhibitor of the sarcoplasmic/endoplasmic reticulum calcium ATPase pump that ind

Asthma-like symptoms, methacholine hyperresponsiveness, and use of asthma medication are prevalent in elite cross-country skiers. We quantitated mucosal inflammatory cell infiltration and tenascin expression in the subepithelial basement membrane in endobronchial biopsy specimens of the proximal airways from 40 elite, competitive skiers (mean: 17.5; range: 16 to 20 yr) without a diagnosis of asthm

Background Type 2 diabetes (T2D) is a multifactorial disease in which environmental triggers interact with genetic variants in the predisposition to the disease. A number of common variants have been associated with T2D but our knowledge of their ability to predict T2D prospectively is limited. Methods and Findings By using a Cox proportional hazard model, common variants in the PPARG (P12A), CAPN

AIMS/HYPOTHESIS: We examined features of the metabolic syndrome to see if they modified the risk of chronic diabetic complications in patients with Type II (non-insulin-dependent) diabetes mellitus. METHODS: A total of 85 randomly selected patients with the metabolic syndrome (WHO definition) were compared with 85 Type II diabetic patients matched for age, sex, duration of diabetes, glycaemic cont

The purpose of this investigation was to evaluate the role of corticotropin releasing factor (CRF) on micturition. CRF is involved in the endocrine and central nervous system responses to stress and is also expressed in sites responsible for the control of micturition. In this investigation, cystometric experiments were performed in awake and unrestrained Wistar rats and on Spontaneous Hypertensiv

In this pilot study, the predictive value of Octreotide scintigraphy (Octreoscan) and/or Chromogranin-A (CgA) was investigated in patients with hormone-refractory prostate cancer treated with Octreotide acetate. In total, 20 patients with progressive disease and bone metastases entered the trial. At baseline Octreoscan, CgA, PSA, alkaline phosphates (ALP) and two self-administered questionnaires (

Background During the last 15 years, high-dose chemotherapy with autologous hematopoietic stem cell transplantation (HSCT) has globally been performed for severe multiple sclerosis (MS). Most patients have been in progressive phase with long disease duration. As a rule, treatment effect has been minor or moderate. Patients Since 2004, we have performed HSCT in nine young patients with "malignant"

Asymmetrical flow field-flow fractionation (AsFIFFF) in combination with multi-angle light scattering (MALS) was applied to cationic potato amylopectin (CPAP) to investigate how molar mass, root-mean-square (r.m.s.) radius and shape was influenced by different conditions of jet-cooking. The effect of different jet-cooking temperatures in the range 110 degrees C - 140 degrees C was studied in an ex

Background & Aims: Preterm birth and formula feeding are key risk factors associated with necrotizing enterocolitis (NEC) in infants, but little is known about intestinal conditions that predispose to disease. Thus, structural, functional, and microbiologic indices were used to investigate the etiology of spontaneous NEC development in preterm pigs. Methods : Piglets were delivered by cesarean

Klassiska professioner tappar mark Gerdahallen väcker känslor Forskarröster i samhällsdebatten Glädjeskutt Lunds universitets magasin | nr 1 | 2015 för nätutbiLdning åt aLLa 2 LUM nr 1 | 2015 LUM nr 1 | 2015 3 3 t Nyinstallerade rektorn vill värna och utveckla studentinflytandet Studenterna, omvärlden och vägen till akademisk framgång! Det var viktiga punkter i Torbjörn von Schantz installationsta

https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-1-2015.pdf - 2026-05-30

Bilaga 1 - Fördelning av ansvar och beslutsbefogenheter samt delegationer inom CEC, beslut 2018-04-09, STYR 2018/495 Fördelning av ansvar och beslutsbefogenheter samt delegationer inom CEC från och med 2018-04-16 Föreståndare Motsvarar prefekt, se gällande chefskontrakt och arbetsordning vid naturvetenskapliga fakulteten. Övergripande formellt ansvar och övergripande verksamhetsansvar. Ekonomi: ob

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/delegationsordning_cec_2018-04-16.pdf - 2026-05-30

Brevmall Postadress Box 114,221 00 Lund Besöksadress Paradisgatan 5, hus G Telefon växel 046-222 00 00 Fax 046-222 41 00 Webbadress http://www.soc.lu.se Soc io log iska ins t i tu t ionen Schema Delkurs 1 (period 1-2) Kriminologisk teori och forskning 15 hp *Se adresser till lokaler på sista sidan Datum Tid Rum Lära re Aktivitet Innehåll 2/9 13-16 Stadshallens sessionssal* KG Kurs-information Obli

https://www.soclaw.lu.se/sites/soclaw.lu.se/files/schema_soca73.pdf - 2026-05-30

https://www.cfe.lu.se/en/sites/cfe.lu.se.en/files/2024-01/Europeiska%20uppta%CC%88ckter.pdf - 2026-05-30

https://www.cfe.lu.se/en/sites/cfe.lu.se.en/files/2024-01/Olof%20B%C3%A4rt%C3%A5s%20(1).pdf - 2026-05-30

Utvecklingsplan för psykologprogrammet Sida 1 av 19 Fakultetsstyrelsen UTVECKLINGSPLAN Diarienummer STYR 2021/2460 Datum 2023-03-16 Utvecklingsplan psykologprogrammet Inledning Under våren 2022 har Psykologprogrammet (PSP) genomgått en utvärderingsprocess som inbegripit en självvärdering och återkoppling från en extern sakkunniggrupp. Utvärderingsprocessen följer de gemensamma kriterierna för kval

https://www.sam.lu.se/internt/sites/sam.lu.se.internt/files/2023-07/Utvecklingsplan_Psykologprogrammet_beslut.pdf - 2026-05-30

Nytt ljus över istiden Stor EU-satsning mot barnlöshet MAX IV på rätt väg Utsatt LUNDS UNIVERSITETS MAGASIN | NR 2 | 2019 HAT OCH HOT MOT FORSKARE ÖKAR 2 LUM NR 2 | 2019 LUM NR 2 | 2019 3 Tidningar, tidningar, tidningar…. Just nu flyttas runt 7000 pallar med dagstidningar från ett nedgånget magasin i Hög. Silverfiskar och an- nan ohyra ska frysas bort från sköra tidningssidor som vittnar om allt f

https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-2-2019.pdf - 2026-05-30

Mental illness has increasingly become a problem throughout the world and is believed to cost the global economy $16 trillion by 2030. Consequently, a growing body of literature investigates the possible causes of mental illness and more specifically, possible early life circumstances which may affect adult mental health. Limited research exists though in terms of exposure to recessions in utero a

With the use of electrogoniometers wrist positions and movements were measured in 13 milkers while working in a modern rotary milking system. The rotary system put considerable demands on the wrists and hands regarding both velocities and repetitiveness. Values were found close to those described in other repetitive industrial work with high risk of wrist and hand disorders. For the right hand the

The aspartic protease cathepsin D, a poor prognostic indicator of breast cancer, is abundantly secreted as procathepsin D by human breast cancer cells and self-activates at low pH in vitro, giving rise to catalytically active cathepsin D. Due to a lower extracellular pH in tumor microenvironments compared to normal tissues, cathepsin D may cleave pathophysiological substrates contributing to cance