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BACKGROUND: The increasing number of survivors after childhood cancer requires characterization of the late complications of these diseases and their treatment. We examined a large number of possible socio-economic late effects following treatment for acute lymphoblastic leukemia (ALL) in order to identify factors leading to a poor outcome. PROCEDURE: All individuals who had been diagnosed with AL
Screening for abdominal aortic aneurysm (AAA) among 65 year old men has been proven cost-effective, but nowadays is conducted partly under new conditions. The prevalence of AAA has decreased, and endovascular aneurysm repair (EVAR) has become the predominant surgical method for AAA repair in many centers. At the Malmö Vascular Center pharmacological secondary prevention with statins, antiplatelet
The conceptual shift in expectations of wireless users from voice towards multimedia, from availability towards acceptable quality, and from stand-alone towards group-oriented computing has a big impact on the needs of today's networks in terms of mobility, quality of service (QoS) support, and multicasting. Ad hoc networks can provide users with these features. However, it is necessary to develop
Popular Abstract in Swedish Att mäta kroppsställningar och rörelser under arbete Belastningsskador är vanliga och medför höga kostnader, både för de drabbade och för samhället. Kvinnor som arbetar med repetitivt arbete, t.ex. monteringsarbete och livsmedelshantering (fiskberedning och kycklingslakt), drabbas ofta, särskilt i nacke, axlar, armar och händer. De åtgärder som genomförts på arbetsplatWork-related musculoskeletal disorders of the neck and upper limb are a major problem. Women in repetitive manual work is one large affected group. Preventive actions are hampered by the lack of knowledge regarding quantitative exposure-response relations for physical workload. The present work shows, that available electrogoniometers are, with a sampling frequency of 20 Hz, feasible for measurin
I bokens första studie, "Samhällsbyggarnas tv-undervisning. Estetik och ideologi i utbildningsprogram för televisionen" författad av Ann-Kristin Wallengren, ställs frågan om hur ett programs form och estetik är kopplat till samtidens samhällsbild och ideologier. Genom analyser av ett antal samhällskunskapsprogram för skolbarn visas hur utbildningsprogrammen från 1960-talet och framåt har förändrat
Popular Abstract in Swedish Syftet med denna avhandling är att förstå och förklara frivården, som organisation och som praktik samt att få en fördjupad förståelse av förhållandet mellan stöd och kontroll. Avhandlingen bygger på två empiriska material. En studie av arkivhandlingar och publicerade texter från 1820-2000. En intervjustudie där tjugo frivårdsklienter, tjugo handläggare och tio lekmannaThe purpose of this thesis is to gain a deeper understanding of the relationship between support and control. The purpose is reached by a study of the probation service as an organization and the practical side of its work The thesis is based on two empirical studies. One is a study of records and published texts from the period 1820-2000. The second is an interview study, in which twenty probatio
Research evaluation practices linked to social impact have important systemic effects on the prioritization and organization of research while at the same time leading to the delivery of higher social value. Amidst growing criticisms, global research evaluation has evolved in a different direction, characterized by quantitative metrics and mimetic behavior. The article deals with the forces that sResearch evaluation practices linked to social impact have important systemic effects on the prioritization and organization of research while at the same time leading to the delivery of higher social value. Amidst growing criticisms, global research evaluation has evolved in a different direction, characterized by quantitative metrics and mimetic behavior. The article deals with the forces that s
The need for digital building information is increasing, both in the form of 3D city models (as geodata) and of more detailed building information models (BIM). BIM models are mainly used in the architecture, engineering and construction industry, but have recently become interesting also for municipalities. The overall aim of this paper is to study one way of dividing a building, namely the divis
In mammals, primordial germ cells (PGCs) are the embryonic cell population that serve as germ cell precursors in both females and males. During mouse embryonic development, the majority of PGCs are arrested at the G2 phase when they migrate into the hindgut at 7.75-8.75 dpc (days post coitum). It is after 9.5 dpc that the PGCs undergo proliferation with a doubling time of 12.6 h. The molecular mec
OBJECTIVE: The mechanisms underlying the association between diabetes and inner ear dysfunction are not known yet. The aim of the present study is to evaluate the impact of obesity/insulin resistance on inner ear fluid homeostasis in vivo, and to investigate whether the organ of Corti could be a target tissue for insulin signaling using auditory House Ear Institute-Organ of Corti 1 (HEI-OC1) cells
Monoterpenoid indole alkaloids (MIAs) are produced as plant defence compounds. In the medicinal plant Catharanthus roseus, they comprise the anticancer compounds vinblastine and vincristine. The iridoid (monoterpenoid) pathway forms one of the two branches that feed MIA biosynthesis and its activation is regulated by the transcription factor (TF) basic helix-loop-helix (bHLH) iridoid synthesis 1 (
The Wilms' tumor gene 1 (WT1) is recurrently mutated in acute myeloid leukemia. Mutations and high expression of WT1 associate with a poor prognosis. In mice, WT1 cooperates with the RUNX1/RUNX1T1 (AML1/ETO) fusion gene in the induction of acute leukemia, further emphasizing a role for WT1 in leukemia development. Molecular mechanisms for WT1 are, however, incompletely understood. Here, we identif
Narrow resonances decaying into WW, WZ or ZZ boson pairs are searched for in 36.7 fb−1 of proton–proton collision data at a centre-of-mass energy of s=13 TeV recorded with the ATLAS detector at the Large Hadron Collider in 2015 and 2016. The diboson system is reconstructed using pairs of large-radius jets with high transverse momentum and tagged as compatible with the hadronic decay of high-moment
This thesis deals with the design and synthesis of rhodium and iridium bis-η2 diolefin catalysts and their applications in C–C bond formation and asymmetric catalysis.More specifically, the second chapter describes the development of inter- and intramolecular (5+2) cycloadditions catalyzed by cationic iridium(I) complexes that lead to the formation of seven-membered rings in a single step. DFT was
Many automated gating algorithms for flow cytometry data are based on the concept of unimodal cell populations. However, in this article, we show that criteria previously used to make decisions on unimodality cannot adequately distinguish unimodal from bimodal densities. We show that dip and bandwidth tests for unimodality, taken from the statistics literature, can do this with consistent and low
