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The present study aimed to increase understanding of how singing activities may be initiated in primary school, and what support and assistance teachers require to conduct singing activities as an integrated part of the school day. Five music teachers participated in a focus group interview. The following main themes were identified: 1) pedagogical and methodological flexibility, 2) the role of ro

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BACKGROUND: This study aimed to evaluate the prevalence of pathogenic/likely pathogenic cardiomyopathy variant carriers in a multiancestry US population and examine the risk of adverse clinical outcomes. METHODS: This retrospective cohort study included multiancestry US adults aged ≥18 years with sequencing data from the All of Us Research Program. Pathogenic/likely pathogenic variants in cardiomy

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(1) Background: Reconditioning of the paraspinal lumbar extensor muscles by isolated lumbar extension resistance exercises (ILEX) has shown good clinical results for patients with chronic unspecific low back pain. However, the clinical value and safety for patients with specific spine pathologies is unclear. In this study, clinical outcome and influencing factors were retrospectively analyzed for

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Purpose: To analyse and compare the number and interval of anti-vascular endothelial growth factor (anti-VEGF) injections in neovascular age-related macular degeneration (nAMD), as well as the visual development in patients followed up for one to three years in clinical practice and during different index periods. Methods: This observational study included treatment-naïve eyes with nAMD from the S

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In the new normality brought by the COVID-19 pandemic, most governments have to adopt containment measures in order to control the spread of the virus. This paper addresses the adequacy and effectiveness of containment measures implemented by the 19 dierent autonomous regions in which Spain is subdivided. The study focuses on the heterogeneity and lack of simultaneity of measures applied by the re

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Apolipoprotein A-I (ApoA-I) is the most predominant protein of high-density lipoprotein (HDL), which is an essential component for reverse cholesterol transport (RCT). ApoA-I has many health-promoting functions, such as anti-atherosclerosis and antioxidant properties; however, carriers of certain rare mutations in the APOA1 gene suffer from a disease called hereditary ApoA-I-related amyloidosis. A

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Subjects with impaired glucose tolerance (IGT) are usually overweight and exhibit insulin resistance with a defective compensation of insulin secretion. In this study, we sought to establish the interrelation between insulin secretion and insulin sensitivity after oral glucose in non-obese subjects with IGT and we also examined this interrelation in relation to the 2 main incretins, glucagon-like

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Asthma is a chronic inflammatory disease of the airways, affecting and disablingapproximately 300 million people worldwide. The inflammatory profile ischaracterized by infiltration of eosinophils, which are a rich source of factors thatare implicated in tissue remodeling. The chronic inflammatory response and theremodeled phenotype create a hospitable environment for secondary bacterialinfections.

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Background: Evidence-based guidelines for assessing pituitary function in children remain limited. Improved understanding of paediatric pituitary diseases may improve clinical management and patient counselling.Aim: This thesis aimed to evaluate diagnostic aspects of paediatric pituitary diseases, focusing on radiological follow-up of pituitary microadenomas and cysts, pituitary refractoriness to

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An integrated framework is introduced and applied to assess the health impact of airborne pollution with greater physiological relevance, moving beyond conventional exposure metrics. Measured particle number size distribution data was integrated with a regional respiratory tract deposition fractions to estimate total and alveolar deposited particle surface area concentrations. Land use regression

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Climate change and its associated extreme events challenge the effectiveness of passive building design strategies. Hybrid passive-active systems emerge as a promising solution; however, their resilience in extreme climate conditions is less studied. This study addresses this gap by investigating the integration of solar chimneys (SC) with variable refrigerant flow (VRF) systems to improve thermal

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Background: Patients with diabetes admitted to emergency care face a higher risk of complications, including prolonged hospital stays, admissions to the intensive care unit and mortality. Aim: To develop a machine learning (ML) model to predict 30-day mortality in patients with diabetes admitted to the emergency department (ED). Design and setting: A cohort study utilizing data from all nine ED’s

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Many studies that use an automated sorption balance to determine a water vapor sorption isotherm for wood collect data until the moisture content change is less than or equal to 0.002% min−1 (20 µg g−1 min−1). This stop criterion has been claimed to give errors in equilibrium moisture content (EMC) predictions of less than 0.001 g g−1 but over the past 10 years, studies have shown that the actual

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Background: Wrist osteoarthritis (OA) is mainly posttraumatic, affects younger individuals than other types of OA, and can lead to significant disability. The first-line treatment is patient education and exercise, but surgery may be considered if symptoms persist. A mini-invasive surgical approach for wrist OA is partial wrist denervation, which,in theory, alleviates pain by resecting sensory ner

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A search for dark mesons originating from strongly-coupled, SU(2) dark flavor symmetry conserving models and decaying gaugephobically to pure Standard Model final states containing top and bottom quarks is presented. The search targets fully hadronic final states and final states with exactly one electron or muon and multiple jets. The analyzed data sample corresponds to an integrated luminosity o

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Objectives To study the prevalence of and interplay between common neuropsychiatric sequelae 3-4 years after onset of first-ever stroke - specifically post-stroke fatigue (PSF), post-stroke depression (PSD) and post-stroke cognitive impairment (PSCI). Design Population-based cohort study. Setting Catchment area of a Swedish University Hospital. Participants We recruited individuals with first-ever

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Sexual and Reproductive Health and Rights (SRHR) is suggested to be solved by policies and action plans. However, post-structural scholars argue that discourses shape policies, and their solutions. The policy discourse on women with disabilities’ SRHR needs has not been given much attention, especially in the context of Africa. Therefore, this study questions how SRHR is represented in relation to

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När är en bild barnpornografisk? Frågan kan utredas rättsdogmatiskt, men också empiriskt genom att domstolarnas prövningar av misstänkt barnpornografiska bilder undersöks. Det är inte självklart att de olika utredningsmetoderna ger samstämmiga svar; domare dömer inte nödvändigtvis på ett sätt som överensstämmer med gällande rätt. I den här undersökningen jämfördes innebörden av barnpornografi enliWhen does an image constitute child pornography? The issue can be investigated with a legal dogmatic method, but also with an empirically method and by examining the courts' trials regarding suspected child pornographic material. It is not obvious that the different methods of investigation provide consistent answers; judges do not necessarily decide in a manner consistent with applicable law.

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The discovery of the Higgs boson h in 2012 further confirmed the remarkable accuracy of the Standard Model (SM). Despite this, some compelling excesses in multi-lepton final states were recorded in both major runs of the Large Hadron Collider (LHC). The excesses can be explained by the introduction of a model where a heavy boson X decays into a SM Higgs boson h and a singlet scalar S with Higgs-li