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In this study we derive analytically the equilibrium melting probabilities for basepairs of a DNA molecule with a defect site. We assume that the defect is characterized by a change in the Watson-Crick basepair energy of the defect basepair, and in the associated two stacking energies for the defect, as compared to the remaining parts of the DNA. The defect site could, for instance, occur due to D

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Purpose: To describe a new time-saving threshold visual field–testing strategy—Swedish Interactive Thresholding Algorithm (SITA) Faster, which is intended to replace SITA Fast—and to report on a clinical evaluation of this new strategy. Design: Description and validity analysis for modifications applied to SITA Fast. Methods: Five centers tested 1 eye of each of 126 glaucoma and glaucoma suspect p

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The aim is to prospectively investigate both the “cohesion” and “network” perspectives of social capital in relation to total, cardiovascular (CVD), cancer and all other causes mortality. The 2008 public health survey in Scania was a postal questionnaire with three letters of reminder, and it was answered in the Autumn by 28,198 respondents (55% participation) aged 18–80 from a stratified random s

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OBJECTIVE Diabetic nephropathy is a serious complication of type 1 diabetes. Recent studies indicate that end-stage renal disease (ESRD) incidence has decreased or that the onset of ESRD has been postponed; therefore, we wanted to analyze the incidence and time trends of ESRD in Sweden. RESEARCH DESIGN AND METHODS In this study, patients with duration of type 1 diabetes >14 years and age at onset

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Objective Polymorphisms in the CYP2R1 gene encoding Vitamin D 25-hydroxylase have been reported to correlate with circulating levels of 25-OH vitamin D3 (25(OH)D). It is unknown whether these variations also affect overall bone metabolism. In order to elucidate the overall associations of polymorphisms in the CYP2R1, we studied haplotype tagging single nucleotide polymorphisms (SNPs) in the gene a

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Corrugated tubes are widely used in a range of applications for heat transfer enhancement. The spirally corrugated tube has a better heat transfer performance than the smooth tube. In this paper, the heat transfer performance of a hybrid smooth and six-start spirally corrugated tube is studied. With a validated numerical model, the effects of the corrugation part length on the vortex in the downst

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In the present study, an electrophoretic deposition method was employed to modify copper surfaces withCu-Zn (100 nm) nanoparticles. Pool boiling heat transfer of HFE-7200 on the modified surfaces was experimentally studied. The results showed that the heat transfer coefficient on the modified surfaces was significantly enhanced compared with that on a smooth surface, e.g., a maximum 100% enhanceme

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In this work, the effects of thermal buoyancy and rotation angle on the hydrodynamics and mixed convection heat transfer characteristics over four heated identical square cylinders placed in a parallel horizontal channel are numerically studied. For the flow field, the Lattice Boltzmann method (LBM) with multiple relaxation time collision operator (MRT) is implemented and the Bhatnagar-Gross-Ktook

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In the present study, the optimal objective effect on the thermal performance of a rectangular duct with pin fins and dimples/protrusions is introduced. Four different optimal objectives are selected (entropy generation, entransy dissipation, enerty, and volume goodness factor). The baseline k-ù turbulence model is applied to solve the governing equations. The multi-island genetic algorithm (MIGA)

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Background: Proton-pump inhibitors (PPIs) have been reported to increase the risk of community-associated Clostridium difficile infection (CDI), but the association remains disputed. Methods: A nationwide cohort study among adults in Denmark, 2010-2013, linking register data on C. difficile testing, filled prescriptions, and patient characteristics. All incident episodes of community-associated CD

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As a classical polymer acceptor material, N2200 has received extensive attention and research in the field of polymer solar cells (PSCs). However, the intrinsic properties of ground- and excited-states in N2200, which are critical for the application of N2200 in PSCs, remain poorly understood. In this work, the ground- and excited-state properties of N2200 solution and film were studied by steady-

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When measuring inequality using conventional inequality measures, ethical assumptions about distributional preferences are often implicitly made. In this paper, we ask whether the ethical assumptions underlying the concentration index for income-related health inequality and the Gini index for income inequality are supported in a representative sample of the Swedish population using an internet-ba

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Background: After a heart failure (HF) hospital discharge, the risk of a cardiovascular (CV) related event is highest in the following 100 days. It is important to identify factors associated with increased risk of readmission. Method: This retrospective, population-based study examined HF patients in Region Halland (RH), Sweden, hospitalized with a HF diagnosis between 2017 and 2019. Data regardi

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Background The genetic background of general obesity and fat distribution is different, pointing to separate underlying physiology. Here, we searched for metabolites and lipoprotein particles associated with fat distribution, measured as waist/hip ratio adjusted for fat mass (WHRadjfatmass), and general adiposity measured as percentage fat mass. Method The sex-stratified association of 791 metabol

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BackgroundEducation is expected to bring about positive behavioral changes which could lead to improved health behaviors. Parental education is a primary determinant of child health and development. However, some evidence showed inverse associations between high parental education and recommended infant and young child feeding (IYCF) in Bangladesh. How the association of parental education differs

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The purpose of this study is to evaluate the safety of people located in discotheques in case of fire. A quantitative fire riskanalysis (QRA) for three different types of discotheques is carried out. The analysis is based on performance based codes from which fire protection alternatives are analysed. The results of the quantitative fire riskanalysis are described as risk profiles and average risk

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This thesis deals with the enforcement of intellectual property rights as an abuse of dominance. In particular after refusal to license a patent, which is essential for a standardized technology. Seeking for injunction relief may in some circumstances violate applicable competition law. The analysis will provide a hint, whereas patent holder who is dominating in particular market can or should be

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When a country liberalizes trade through lowering taxes on imports, it stands before a number of challenges. Recovering lost trade tax revenue is one of them. Cape Verde is one of the countries that are currently negotiating an Economic Partnership Agreement with the EU and studies predict that the tariff reductions resulting from the agreement may have a severe impact on Cape Verde’s government r

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Studien vände sig till personal, olika yrkesgrupper, som arbetar med krigsskadade och torterade i Sverige. Syftet var att beskriva personalgruppens mående och tillväxt i relation till arbetet, inställning till död, ondska och förlåtelse samt bakgrundsvariabler (t.ex eget trauma och arbetssituation) och undersöka samband mellan dessa. 69 traumaarbetare svarade på ett frågeformulär som mätte dessa fThe 69 participants of this study were Swedish personnel of various occupations, working at centers for war and torture survivors. The aim was to describe the personnel’s reactions from their work, their background (e.g. trauma prevalence, work situation), their attitude towards death, evil, and forgiveness and the relationships between these. The results of this study show that the participants h