Filtyp
The development of lipid nanoparticle (LNP) based therapeutics for delivery of RNA has triggered the advance of new strategies for formulation, such as high throughput microfluidics for precise mixing of components into well-defined particles. In this study, we have characterised the structure of LNPs throughout the formulation process using in situ small angle x-ray scattering in the microfluidic
BACKGROUND: To clarify, in a national sample, associations between risk for seven psychiatric and substance use disorders and five key transitions in Sweden's public educational system. METHODS: Swedish-born individuals (1972-1995, N = 1 997 910) were followed through 12-31-2018, at mean age 34.9. We predicted, from these educational transitions, risk for major depression (MD), obsessive-compulsiv
During the last decades, there has been continuous development of nationwide quality registries to assess healthcare and to do research in Sweden. An important background motive is the demographic transition resulting from an increasingly ageing population as one of the most important challenges of our time and a growing concern in many European countries and elsewhere. One condition for meeting t
OBJECTIVE: Genome-wide association studies have begun to elucidate the genetic architecture of type 2 diabetes. We examined whether single nucleotide polymorphisms (SNPs) identified through targeted complementary approaches affect diabetes incidence in the at-risk population of the Diabetes Prevention Program (DPP) and whether they influence a response to preventive interventions. RESEARCH DESIGN
I en tid då företag avkrävs mer ansvar och deras hållbarhetsinitiativ (socialt, ekonomiskt och miljömässigt) granskas i större utsträckning undersöker denna uppsats hur FN:s nya globala mål för hållbar utveckling påverkar företagens arbete. Uppsatsen består huvudsak-ligen av en studie där Telia Company och deras arbete för Förenta Nationernas (FN) 17 globala mål för hållbar utveckling studeras. St
Title: Mapping the usage of returnable packaging material and a proposal for improvements - a Case Study at Haldex AB in Landskrona Author: Annika Jönsson Supervisor: Enes Hasic & Anders Pålsson, Haldex AB, Landskrona Eva Berg, Department of Industrial Management and Logistics, Division of Engineering Logistics, Faculty of Engineering, Lund University Examiner: Jan Olhager, Department of Indus
Syftet med denna studie var att undersöka om rekryterares personlighet, baserat på de personlighetsdimensionerna från Big Five, men även social önskvärdhet, är relaterat till preferens för särskilda rekryteringsmetoder i en rekryteringsprocess. Social önskvärdhet mättes genom den evaluativa faktorn, som kan beskrivas som en preferens för evaluativ information och en tendens att beskriva sig själv
The technological development and above all the internet has had a major impact on international trade. The ability to transfer data within companies, but also between companies and countries is an essential part of this development and the ability to transfer data today is a central component of companies’ everyday activities. In practice, a company cannot do business, or engage in trade, without
Förändring av individens anknytning till sociala nätverk kan vara ett sätt att få en tidigare kriminell och/eller missbrukare att värdera ett konformt liv. Detta med en förhoppning om att ersätta individens kriminella värden och attityder till konforma sådana, genom att individen associerar och identifierar sig med gruppen (det sociala nätverket). Med utgångspunkt i denna idé är därför vårt syfte
Sammanfattning I denna studie utreds vad som gäller för att ett äganderättsförbehåll skall vara sakrättsligt giltigt enligt den svenska rättsordningen, och om det bör införas äganderättsförbehåll som ger den som säkerställt egendomen ett sakrättsligt starkare skydd än idag, dvs. om den som sålt en vara på kredit bör ges större möjlighet att ta tillbaka de levererade varorna till följd av köparens Summary This study investigates the requirements for when the retention of title clause is under indefeasible protection in the Swedish legal system, and if the legal effect of the Swedish retention of title clause should be amended to give the person who sold goods on credit a greater opportunity to take back the goods that has been delivered, as a result of the buyer's non-payment. The curre
Some markets represent companies that offer similar products in terms of design, quality and price. In this reality competitive advantages have to be created and developed in other ways. Many companies have therefore chosen a market oriented strategy that focuses on the client and their needs. According to studies within the field of Service management the interaction between the company and the c
The field of hybrid human-artificial intelligence (HHAI), although primarily driven by developments in AI, also requires fundamentally new approaches and solutions. Multidisciplinary in nature, it calls for collaboration across various research domains, such as AI, HCI, the cognitive and social sciences, philosophy and ethics, and complex systems, to name but a few. This book presents the proceedi
Increasing recognition of germline DDX41 variants in patients with hematological malignancies prompted us to provide DDX41-specific recommendations for diagnosis, surveillance, and treatment. Causative germline variants in the DDX41 predispose to the development of myeloid neoplasms (MNs), especially myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). Almost 3%–5% of all patients with
Background and aims: Normative values are lacking regarding intraepidermal nerve fiber density (IENFD) in thin sections of 5 µm. Thus, we aimed to assess IENFD in thin sections in a healthy adult population as well as to investigate whether IENFD is related to age, sex, and site of excision.Methods: Archival skin biopsies or excisions at the Department of Pathology, Lund, Sweden, from arm and leg
The spread of global multistakeholder partnerships (MSPs) for the2030 Agenda for sustainable development has generatedsignificant expectations on policy synergies and transformativegovernance. This article contributes to the study of the currentgeneration of MSPs by focusing on the self-legitimation attemptsthat MSPs undertake to justify their authority. We compare theself-legitimation claims of a
Background and objective: Biparametric magnetic resonance imaging (bpMRI), excluding dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI), is a potential replacement for multiparametric MRI (mpMRI) in diagnosing clinically significant prostate cancer (csPCa). An extensive international multireader multicase observer study was conducted to assess the noninferiority of bpMRI to mpMRI in
Objectives Peak exercise systolic blood pressure (SBP) is associated with future cardiovascular disease (CVD) and mortality. We aimed to evaluate the predictive value of different SBP patterns at the end of exercise with these outcomes. Methods We studied 6329 adults (45% women) referred for exercise testing, with test duration of 6-14 min, maximal effort and valid SBP measurements at the end of e
Nationella prov i låg- och mellanstadiet infördes i Sverige 2011 i samband med den nya läroplanen Lgr11. Syftet med proven var, framför allt i årskurs 3, att agera diagnostiserande och lokalisera elever i behov av extra stöd med målet att öka måluppfyllelsen och stärka likvärdigheten. Denna studie undersöker huruvida införandet av nationella prov i lägre åldrar har uppnått de syftena. Aggregerade
