Implications of AMBRA1 in phenotype switching & MAPK inhibitors response in melanoma
Advanced melanoma has for long been associated with poor prognosis. Recent advance- ments have improved outcomes; however, many challenges are yet to be overcome. Targeted therapy has in recent years been a good option for patients. Despite positive early responses to the treatment, tumours often grow resistant to these therapies over time rendering them ineffective. The development of resistance
