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Background: It is not known to what extent biologic treatment for IBD is captured in the Swedish Prescribed Drug Register (PDR) and the National Patient Register (NPR). Methods: A cross-sectional study from July 2005 until 2017, comparing data on biologic treatment in the PDR and the NPR with medical records. We assessed the proportion of started treatment episodes in the medical records that were

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Recent neuroscientific and technical developments of brain machine interfaces have put increasing demands on neuroinformatic databases and data handling software, especially when managing data in real time from large numbers of neurons. Extrapolating these developments we here set out to construct a scalable software architecture that would enable near-future massive parallel recording, organizati

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Objective: The aim of this investigation was to study differences between male and female patients with stage T1 urinary bladder cancer (UBC) regarding intravesical instillation therapy, second resection and survival. Materials and methods: This study included all patients with non-metastatic primary T1 UBC reported to the Swedish National Register of Urinary Bladder Cancer (SNRUBC) from 1997 to 2

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Background: In neonates with critical pulmonary stenosis (CPS) or pulmonary atresia with intact ventricular septum (PAIVS), a nonrestrictive atrial septal defect (ASD) has been speculated to improve the initial clinical course after pulmonary valvotomy (PV) but some concerns exist in terms of its potentially longterm adverse effect on the right ventricle`s (RV) growth and persistent desaturation d

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The objective of this paper is to optimize the passive design of newly-built residential buildings in hot summer and cold winter region of China for improving indoor thermal comfort while reducing building energy demand. In this respect, this paper investigates the performance of a representative apartment building in the city of Shanghai and evaluates the optimum solutions by using a developed op

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The ATLAS experiment has performed extensive searches for the electroweak production of charginos, neutralinos, and staus. This article summarizes and extends the search for electroweak supersymmetry with new analyses targeting scenarios not covered by previously published searches. New searches use vector-boson fusion production, initial-state radiation jets, and low-momentum lepton final states,

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Abstract: A search is performed for the production of high-mass resonances decaying into a photon and a jet in 3.2 fb−1of proton-proton collisions at a centre-of-mass energy of (Formula presented.) TeV collected by the ATLAS detector at the Large Hadron Collider. Selected events have an isolated photon and a jet, each with transverse momentum above 150 GeV. No significant deviation of the γ+jet in

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Co-creation (or co-production, Voorberg et al., 2015) of public services together with individual service users is based on the assumption that the individual can define her or his own value to be co-created. However, in the case of children, this can be put into doubt, as children do not have the same cognitive perspectives and abilities as adults, and a weaker voice as agents. This results in thCo-creation (or co-production, Voorberg et al., 2015) of public services together with individual service users is based on the assumption that the individual can define her or his own value to be co-created. However, in the case of children, this can be put into doubt, as children do not have the same cognitive perspectives and abilities as adults, and a weaker voice as agents. This results in th

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Hydropower makes up nearly half of Sweden's electrical energy production. However, the distribution of the water resources is not aligned with demand, as most of the inflows to the reservoirs occur during the spring flood period. This means that carefully planned reservoir management is required to help redistribute water resources to ensure optimal production and accurate forecasts of the spring

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Optimisation of radiological protection for operators working with fluoroscopically guided procedures has to be performed during the procedure, under varying and difficult conditions. The aim of the present study was to evaluate the impact of a system for real-time visualisation of radiation dose rate on optimisation of occupational radiological protection in fluoroscopically guided procedures. In

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Three-dimensional (3D) solar maps based on Radiance simulations are presented for a future city district in southern Norway. The surface mapping method provides the commercial developer with a practical tool to evaluate the potential for building integrated photovoltaics (BIPV). The solar maps identify the optimum roof and facade areas available for solar energy utilization. The importance of BIPV

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Longitudinal studies of caregiver burden when caring for persons with dementia living at home are sparse. The aim of the study was to identify factors associated with caregiver burden and predicting increased burden related to caregivers, persons with dementia and formal care. Data were collected through interviews with 1223 caregivers in eight European countries. Bivariate and multivariate regres

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A search is conducted for a beyond-the-Standard-Model boson using events where a Higgs boson with mass 125 GeV decays to four leptons (ℓ = e or μ). This decay is presumed to occur via an intermediate state which contains one or two on-shell, promptly decaying bosons: H → ZX/XX → 4ℓ, where X is a new vector boson Zd or pseudoscalar a with mass between 1 and 60 GeV. The search uses pp collision data

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In the process of object-based change detection (OBCD), scale is a significant factor related to extraction and analyses of subsequent change data. To address this problem, this paper describes an object-based approach to urban area change detection (CD) using rotation forest (RoF) and coarse-to-fine uncertainty analyses of multi-temporal high-resolution remote sensing images. First, highly homoge

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Neuroblastoma is a neural crest-derived childhood tumor of the peripheral nervous system in which MycN amplification is a hallmark of poor prognosis. Here we show that MycN is expressed together with phosphorylation-stabilizing factor CIP2A in regions of the neural plate destined to form the CNS, but MycN is excluded from the neighboring neural crest stem cell domain. Interestingly, ectopic expres

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A palliative cancer diagnosis in a parent has a major impact on many aspects of patients’ children. This article aims to explore how doctors and social workers met children as relatives of a parent with cancer in order to understand the possibilities and difficulties in supporting children in specialised palliative homecare in Sweden. Qualitative, semi-structured interviews of doctors and social w