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Purpose: Preclinical studies using a new treatment modality called FLASH Radiotherapy (FLASH-RT) need a two-phase procedure to ensure minimal uncertainties in the delivered dose. The first phase requires a new investigation of the reference dosimetry lying outside the conventional metrology framework from national metrology institutes but necessary to obtain traceability, repeatability, and stabil
PURPOSE: Paramedial mandibulotomy facilitates access for the resection of tumors in the oral and oropharyngeal space; however, severe complications related to surgical techniques and radiotherapy have been reported for this procedure. This study evaluated whether preservation of the periosteum during a mandibulotomy would decrease postoperative complications owing to the increased healing capacity
Reliable prediction tools are yet to be developed for estimating the accurate acoustic performance of lightweight structures, which are vital especially in the design process. This paper presents a sound insulation prediction model based on artificial Neural Networks (NN) to estimate acoustic performance for airborne and impact sound insulation of floor structures. At an initial stage, the predict
AimIntraoperative rectal washout is performed to eliminate exfoliated intraluminal cancer cells and thereby decrease the risk of local recurrence. Rectal washout in abdominoperineal resection has not been studied. The aim of this study was to assess the oncological outcome after rectal washout in abdominoperineal resection for rectal cancer and to find evidence as to whether rectal washout should
Binge eating disorder (BED) is associated with several psychological and medical problems, such as obesity. Approximately 30% of individuals seeking weight loss treatments present binge eating symptomatology. Moreover, current treatments for BED lack efficacy at follow-up assessments. Developing mindfulness and self-compassion seem to be beneficial in treating BED, although there is still room for
This two-part paper investigates the application of artificial intelligence (AI) and in particular machine learning (ML) to the study of wireless propagation channels. In Part I, we introduced AI and ML as well as provided a comprehensive survey on ML enabled channel characterization and antenna-channel optimization, and in this part (Part II) we review state-of-the-art literature on scenario iden
This paper investigates the wideband channel characteristics obtained in a classroom and a hall indoor scenarios at 2-4, 9-11 and 27-29GHz. A virtual uniform circular array (UCA) based channel sounding system was utilized to capture wideband spatial channel characteristics. The propagation parameters of multipath components (MPCs) were estimated by using a high resolution parameter estimation (HRP
BACKGROUND: Positive margins after breast-conserving surgery (BCS) and subsequent second surgery are associated with increased costs and patient discomfort. The aim of this study was to develop a prediction model for positive margins based on risk factors available before surgery. METHODS: Patients undergoing BCS for in situ or invasive cancer between 2015 and 2016 at site A formed a development c
Importance: Local steroid injection is commonly used in treating patients with idiopathic carpal tunnel syndrome, but evidence regarding long-term efficacy is lacking. Objective: To assess the long-term treatment effects of local steroid injection for carpal tunnel syndrome. Design, Setting, and Participants: This exploratory 5-year extended follow-up of a double-blind, placebo-controlled randomiz
Intrinsic molecular subtypes may explain marked variation between bladder cancer patients in prognosis and response to therapy. Complex testing algorithms and little attention to more prevalent, early-stage (non-muscle invasive) bladder cancers (NMIBCs) have hindered implementation of subtyping in clinical practice. Here, using a three-antibody immunohistochemistry (IHC) algorithm, we identify the
This paper presents the numerical study of soot formation and oxidation processes across different ambient temperatures (900K, 1000K, and 1100K) and oxygen levels (15% and 21% O2) using large eddy simulation coupled with a two-equation soot model. The predicted ignition delay time, lift-off length and soot distribution show good agreements with the corresponding experimental data. A stronger oxida
To limit global warming to 1.5°C, fossil fuel use must rapidly decline, but historical precedents for such large-scale transitions are lacking. Here we identify 147 historical episodes and policy pledges of fossil fuel decline in 105 countries and global regions between 1960 and 2018. We analyze 43 cases in larger systems most relevant to climate scenarios. One-half of 1.5°C-compatible scenarios e
Critical infrastructures (CIs) and the services they provide are imperative for the functioning of societies. CI safety and security have historically been addressed and regulated on a sectoral basis, despite their interdependent nature. These silo-structures potentially hinder achieving resilience from a system-of-systems governance perspective. Cross-sectoral initiatives addressing interdependen
The possibility to investigate complex magnetic profiles throughout an ultrathin magnetic film or an interface by soft x-ray resonant magnetic reflectivity is presented. The determination of in- and out-of-plane magnetic profile is shown to be possible with a subnanometer resolution by measuring the reflectivity over a wide angular range. The technique is applied to a granular magnetic multilayer
We have built a new small furnace to perform high temperature studies up to 1200°C in vacuum or in oxygen atmosphere. This furnace was originally used as a catalytic reactor optimized for the in situ X-ray Absorption Spectroscopy experiments on beamline ID24. It has now been redesigned for use on the ESRF beamline ID01 for in situ Grazing Incidence Small Angle X-ray Scattering experiments. For the
Radiocarbon (14C), as a consequence of its production in the atmosphere and subsequent dispersal through the carbon cycle, is a key tracer for studying the Earth system. Knowledge of past 14C levels improves our understanding of climate processes, the Sun, the geodynamo, and the carbon cycle. Recently updated radiocarbon calibration curves (IntCal20, SHCal20, and Marine20) provide unprecedented ac
As part of the IEA-SHC Task 41 'Solar Energy and Architecture' an international survey was carried out. This paper presents its results for Subtask B which especially focuses on methods and tools for solar design applied by architects. Building professionals, mainly architects, were contacted via email and asked to participate in a web-based questionnaire about their use of methods and tools for s
