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Vertigo is one of the most common complaints in medicine. Despite its high prevalence, patients with vertigo often receive either inappropriate or inadequate treatment. The most important reasons for this deplorable situation are insufficient interdisciplinary cooperation, nonexistent standards in diagnostics and therapy, the relatively rare translations of basic science findings to clinical appli
Medulloblastomas comprise a heterogeneous group of tumours and can be subdivided into four molecular subgroups (WNT, SHH, Group 3 and Group 4) with distinct prognosis, biological behaviour and implications for targeted therapies. Few experimental models exist of the aggressive and poorly characterized Group 3 tumours. In order to establish a reproducible transplantable Group 3 medulloblastoma mode
The desert woodrat complex (Neotoma lepida group) is a set of four closely related species occupying the arid lands of western North America. We have developed 18 polymorphic microsatellite loci to analyse the population structure, mating patterns, and hybridization at points of contact between the contiguously allopatric species in the complex.
Forested countries in the global south that have agreed to engage in REDD+, a policy mechanism for addressing climate change, are receiving support to improve laws, policies, systems and structures. As a mechanism initiated at the global level and seeking to use forests to address a global commons crisis (atmospheric carbon concentration), understanding how REDD+ translates into implementation at
BACKGROUND: Minimally invasive parathyroidectomy (MIP) has been introduced for the treatment of patients with primary hyperparathyroidism (pHPT). Thus far, only one randomized trial has compared video-assisted MIP with conventional bilateral cervical exploration (BCE). The value of open MIP is therefore not known.METHODS: Fifty patients with a solitary parathyroid adenoma localized before surgery
In this study, a tank-connected food waste disposer system with the objective to optimise biogas production and nutrient recovery from food waste in Malmö was evaluated. The project investigated the source-separation ratio of food waste through waste composition analyses, determined the potential biogas production in ground food waste, analysed the organic matter content and the limiting component
The main purpose of this study was to compare two non-invasive optical spectroscopic techniques for assessing peripheral oxygenation saturation in healthy volunteers under specific provocations. The results suggest that the time-resolved technique provides more accurate and robust results.
The integrated urban wastewater system (UWS) consists of different sections that are interconnected. These include: i) catchment; ii) sewer network; iii) wastewater treatment plant (WWTP); and finally, iv) receiving water system. Traditionally, these sections are operated and evaluated individually. However, it is now well-established that all the sections of an UWS should be operated in a holisti
Effective material parameters for diffusion and elastic deformation are calculatedfor porous materials using a continuum theory-based superposition procedure. The theory that is limited to two-dimensional cases, requires that the pores are sufficiently sparse. The methodleads to simple manual calculations that can be performed by, e.g. hospital staff at clinicaldiagnoses of bone deceases that invo
Design and properties are reported for a novel type of multi-channel isothermal microcalorimeter. It is equipped with 48 calorimetric units (channels) and is primarily intended for use as a monitor of the activity of living cells, tissues and small animals. Calorimetric vessels are positioned in a holder with the format of a 48-well microtiter plate. At most, 47 samples can be measured simultaneou
The issue of lag selection in ADF unit root testing is important, even asymptotically, for if the number of lags is not allowed to increase at a certain rate the test might not be correctly sized. However, size control is not the only concern. Indeed, simulations have repeatedly shown how increasing lag lengths tend to be associated with reductions in power, thus adding to the well-known low power
The aim of this paper is to describe, conceptualise and critically discuss how and with what consequences marketing is used to construct a mass market for vegan substitutes. Drawing on the concepts of the marketing device and qualification, it shows how Oatly – a Swedish company making oat-based products – enrols three sets of marketing devices, i.e. digital media, packaging and stores, to simulta
Anomaly detection is the process of identifying unexpected data samples in datasets. Automated anomaly detection is either performed using supervised machine learning models, which require a labelled dataset for their calibration, or unsupervised models, which do not require labels. While academic research has produced a vast array of tools and machine learning models for automated anomaly detecti
Some of the most fundamental chemical building blocks of life on Earth are the metal elements. X-ray absorption spectroscopy (XAS) is an element-specific technique that can analyse the local atomic and electronic structure of, for example, the active sites in catalysts and energy materials and allow the metal sites in biological samples to be identified and understood. A microfluidic device capabl
Objective: To avoid over-treatment of low-risk prostate cancer patients, it is important to identify clinically significant and insignificant cancer for treatment decision-making. However, no accurate test is currently available. Methods: To address this unmet medical need, we developed a novel gene classifier to distinguish clinically significant and insignificant cancer, which were classified ba
Advanced therapies for Parkinson's disease (PD) constitute a broad range of treatments, each presenting specific ethical challenges. Some of these therapies are established and in clinical use, like device-aided therapies, and others, based on advanced therapeutic medicinal products (ATMPs), are still in early stage of clinical trials. This paper focuses on some common ethical issues arising in th
Assignment of the G3m(g) and (b) correlative amino acid residues was performed at the genomic level by direct sequencing of DNA from nine Caucasian individuals. Two oligonucleotide primers were used for subclass-specific enzymatic amplification of a DNA segment comprising a major portion of the second and third constant region domains (CH2 and CH3) fo the human IgG3 heavy chain gene. Comparison of
