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ICOS-ligand triggering impairs osteoclast differentiation and function in vitro and in vivo
Osteoblasts, osteocytes, and osteoclasts (OCs) are involved in the bone production and resorption, which are crucial in bone homeostasis. OC hyperactivation plays a role in the exaggerated bone resorption of diseases such as osteoporosis, rheumatoid arthritis, and osteolytic tumor metastases. This work stems from the finding that OCs can express B7h (ICOS-Ligand), which is the ligand of the ICOS T
S3P vs Arc Vapour deposition coating performance in machining 316L and Ti-6Al-4V
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Oxidation of Ketones: A (Chemo-) Enzymatic Approach Using Oxygenases and Hydrolases
Popular Abstract in English The thesis that you are reading at this moment was printed using climate compensated paper, a sign that consciously or not you are contributing somehow to control the current environmental issues in our planet. It would not be nice if every single article used in your daily life contains information about how environmentally friendly that product is? We have to think “bOxidation reactions are important in organic chemistry as well as in nature. In industry, oxidations are commonly used for the synthesis of chemicals and pharmaceuticals, however such processes have a number of limitations, they use chlorinated solvents, stoichiometric oxidation reagents, and in some cases the reagents that have risks of explosion during transportation and storage. This has called
Stjärnornas fred - En analys av samtiden och hur gällande rätt kan utvecklas
Det går att konstatera att regleringen av rymden befinner sig i en form av rättsligt vakuum. Det saknas idag en tydliga normer för användningen av rymden. Tolkningar av de få traktat som ratificerats av majoritetens av världens länder är vaga och ofta intetsägande. Samtidigt håller en ny rymdkapplöpning på att växa fram. Den här gången har kommersiella aktörer lagt sig i framkant i väst medan glob
Systemic sclerosis. Novel molecular and epidemiological features of disease.
Popular Abstract in Swedish Systemisk skleros (SSc) är en relativt ovanlig reumatologisk sjukdom som kan engagera många av kroppens organ. Sjukdomen kallas ibland också för sklerodermi. Typiskt för sjukdomen är att huden omvandlas till fibros och blir hård och stram över olika delar av kroppen. Typiskt för sjukdomen är också att drabbade patienter har försämrad funktion i sina blodkärl, framförallSystemic sclerosis (SSc) is a systemic rheumatic disease with significant mortality and morbidity. Different estimations of disease prevalence and incidence have been presented from various parts of the world. While lung involvement is a common cause of SSc-related death, a majority of SSc patients suffer from symptoms originating in the gastrointestinal (GI) tract. By combining data from a popu
