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Background Common single-nucleotide polymorphisms (SNPs) that are associated with blood low-density lipoprotein (LDL) or high-density lipoprotein (HDL) cholesterol modestly affect lipid levels. We tested the hypothesis that a combination of such SNPs contributes to the risk of cardiovascular disease. Methods We studied SNPs at nine loci in 5414 subjects from the cardiovascular cohort of the Malmö
dAlcohol intoxication affects the vestibular system and balance control in many ways. We have investigated how acute, moderate (blood alcohol concentrations of 0.06 +/- 0.01%), and high (0.10 +0.02%) alcohol intoxication affects the ability to perceive the visual horizontal and vertical and the visual field dependence measured with the rod and frame tests in 24 healthy participants. Alcohol ingest
Effective treatment of bleeding episodes in hemophilia with high titer inhibitors (HTI) remains a challenge, despite the fact that the therapeutic armamentarium has expanded considerably over the past few years. Treatment safety has improved with the availability of porcine factor VIII (FVIII) and bypassing products such as recombinant factor VIIa (rFVIIa), and plasma-derived activated Prothrombin
Radionuclide therapy is a promising modality for treatment of tumours of haematopoietic origin while the success for treatment of solid tumours so far has been limited. The authors consider radionuclide therapy mainly as a method to eradicate disseminated tumour cells and small metastases while bulky tumours and large metastases have to be treated surgically or by external radiation therapy. The p
Coherent perception of objects in our environment often requires perceptual integration of auditory and visual information. Recent behavioral data suggest that audiovisual integration depends on attention. The current study investigated the neural basis of audiovisual integration using 3-Tesla functional magnetic resonance imaging (fMRI) in 12 healthy volunteers during attention to auditory or vis
Purpose: To compare the outcome of endovascular aneurysm repair (EVAR) versus conventional open repair (OR) in patients with a short, angulated or otherwise challenging proximal neck. Methods: The definition of a challenging proximal neck was based on diameter (>= 28 mm), length (<= 115 mm), angulation (>= 60 degrees), shape (reverse tapered or bulging), and thrombus lining (>50%). Between January
Popular Abstract in Swedish (Populärvetenskaplig sammanfattning) I Skandinavien drabbas 1 av 3 000 människor av en ärftlig näthinnedegeneration som ofta leder till en grav synnedsättning och inte sällan till blindhet. Orsaken är att näthinnans ljuskänsliga celler långsamt förtvinar. Vi kan ännu inte bota dessa sjukdomar. Det finns många olika varianter av ärftlig näthinnedegeneration, vilket gör The purpose of the study was to characterise the phenotype with emphasis on electroretinography in four different types of hereditary retinal degeneration and to correlate it to a genotype when possible. Two methods were used: full-field electroretinography for objective assessment of retinal function and mutation screening of blood samples for detection of gene alterations. Electroretinograms fro
In a world where distributed power generation and deregulation of energy markets are on everyone's agenda, the need for highly efficient power plants with short lead times is greater than ever. Although at present combined cycles provide a solution, development of ever more advanced machines to increase efficiency and lower the environmental impact has led to high maintenance costs and a decrease
This paper proposes Lagrange multiplier (LM) based tests for the null hypothesis of no cointegration in panel data. The tests are general enough to allow for heteroskedastic and serially correlated errors, individual specific time trends, and a single structural break in both the intercept and slope of each regression, which may be located different dates for different individuals. The limiting di
Due to the increasing test data volume needed to test core-based System-on-Chip, several test scheduling techniques minimizing the test application time have been proposed. In contrast to approaches where a fixed test set for each core is assumed, we explore the possibility to use overlapping test patterns from the tests in the system. The overlapping tests serves as alternatives to the original d
This thesis deals primarily with the production of written texts by adults with reading and writing difficulties. Their writing is analysed from three different aspects: error analysis, non-error-oriented text analysis and analysis of the production process. These studies are based on data from on-line recordings of writing. The main question is how the written language production of adults with r
Faster-than-Nyquist (FTN) signaling is a trellis coding method that maintains the error rate while reducing signal bandwidth. The combined effect is to move closer to capacity. We study some basic receiver issues: How to model the signaling efficiently in discrete time, how much the Viterbi receiver can be truncated, and how to combine the method with an outer code. The methods are modeling for mi
