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Background: Breast cancer is the most common female malignancy and the leading cause of cancer-related deaths worldwide. Targeted therapy against the main biomarkers estrogen receptor alpha (ER) and human epidermal growth factor receptor 2 (HER2/ERBB2) have greatly improved mortality rates, but ab initio or acquired therapy resistance is common. It is imperative to identify patients who will benef
Popular Abstract in Swedish I Sverige finns cirka 350 000 personer med diabetes. Motsvarande siffra i hela världen är cirka 350 miljoner människor och forskning talar för att antalet personer med diabetes kommer att öka dramatiskt under de närmsta decennierna. Den största ökningen sker i utvecklingsländer i urbana områden, till stor del beroende på livsstilsförändringar och förändringar i diet. UtSpecific aims: To examine whether the sociodemographic characteristics of patients with type 2 diabetes affect the odds of reaching the recommended treatment goals for HbA1c and blood lipids (study 1). To investigate whether the odds of coronary heart disease are higher in patients with diabetes living in deprived neighborhoods than in those living in wealthy neighborhoods (Study 2). To examine th
BACKGROUND: Serum creatinine is the most commonly used marker for estimation of glomerular filtration rate (GFR). To compensate for its drawbacks as a GFR marker, several prediction equations including several parameters are being used, with the Modification of Diet in Renal Disease (MDRD), Schwartz, and Counahan-Barratt equations being the ones most widely accepted for estimation of relative GFR
The co-administration of the tetravalent meningococcal conjugate vaccine, MenACWY-TT, with a licensed hepatitis A and B vaccine, HepA/B (Twinrix (R)), was compared to their separate administration in this open, randomised, controlled study. Healthy subjects 11-17 years of age (n = 611) were randomised (3:1:1) to receive both vaccines, MenACWY-TT alone or HepA/B alone. The co-administration of both
The authors investigated the role of known risk factors in educational differences in breast cancer incidence. Analyses were based on the European Prospective Investigation Into Cancer and Nutrition and included 242,095 women, 433 cases of in situ breast cancer, and 4,469 cases of invasive breast cancer. Reproductive history (age at first full-term pregnancy and parity), exposure to endogenous and
The synthesis and structural characterization of five Cu(II)-Ln(III) heteronuclear metal-organic frameworks of formula {[Ln(4)Cu(4)(H2O)(26)(bta)(5)]center dot mH(2)O} and {[Ln(4)Cu(4)(H2O)(24)(bta)(5)]center dot pH(2)O} [Ln = La-III (1A/1B), Ce-III (2A/2B), Pr-III (3A/3B), Nd-III (4A/4B) and Sm-III (5A/5B) with m/p = 20 (1A)/16 (1B), 18 (2A)/16 (2B), 14 (3016 (3B), 22 (4A)/16 (4B) and 21 (5A)/14
Background: Type 1 von Willebrand disease (VWD) is a congenital bleeding disorder characterized by a partial quantitative deficiency of plasma von Willebrand factor (VWF) in the absence of structural and/or functional VWF defects. Accurate assessment of the quantity and quality of plasma VWF is difficult but is a prerequisite for correct classification. Objective: To evaluate the proportion of mis
Popular Abstract in English Living organisms are composed of mainly carbohydrate, protein and lipid molecules. Protein molecules are responsible for many biological functions in cells. In order to fulfill their various biological roles, these chain-like molecules must fold into precise three-dimensional shapes. The knowledge of accurate molecular structures is a prerequisite for rational drug desiProtein molecules are responsible for many biological functions in cells. In order to fulfill their various biological roles, these chain-like molecules must fold into precise three-dimensional shapes. The knowledge of accurate molecular structures is a prerequisite for rational drug design and for structure based functional studies. Getting structural information of proteins can be a very difficu
Objectives: NEAT001/ANRS143 demonstrated non-inferiority of once-daily darunavir/ritonavir (800/100 mg) + twice-daily raltegravir (400 mg) versus darunavir/ritonavir + tenofovir disoproxil fumarate/emtricitabine (245/200 mg once daily) in treatment-naive patients. We investigated the population pharmacokinetics of darunavir, ritonavir, tenofovir and emtricitabine and relationships with demographic
On-line supported liquid membrane (SLM) extraction and microporous membrane liquid-liquid extraction (MMLLE) techniques for sample preparation of natural water samples have been developed for the determination of thiophanate-methyl (TM), carbendazim (MBC) and 2-aminobenzimidazole (2-AB) using reversed-phase HPLC. The combination of SLM extraction and MMLLE offers extraction conditions that makes i
OBJECTIVE: To investigate the impact of exercise therapy on molecular biomarkers related to cartilage and inflammation in people at risk of, or with established, knee osteoarthritis by conducting a systematic review of randomized controlled trials (RCTs).METHODS: Literature search up to September 2017 in five major databases with no restriction on publication year or language. Data were extracted
Microsoft Word - LITTERATURLISTA ABMM 51 VT 16.docx LITTERATURLISTA ABMM31 VT 2021 Institutionen för kulturvetenskaper Avdelningen för ABM Godkänd av institutionsstyrelsen, senast reviderad via kursplanegruppen den 2020-12-02 VT 2021 Kurslitteratur ABMM31: Arkivvetenskap: Att samla och organisera kunskap (15 hp) Acker, Amelia. (2018). Data Craft. The Manipulation of Social Media Metadata. Data & S
https://www.ht.lu.se/media/utbildning/dokument/kurser/ABMM31/20211/ABMM31_VT2021.docx - 2026-06-22
Background: Factor V-Short (FV756-1458) is a natural splice variant in which 702 residues are deleted from the B domain. It exposes an acid region (AR2; 1493–1537) that binds tissue factor pathway inhibitor alpha (TFPIα). Protein S also interacts with TFPIα and serves as TFPIα-cofactor in factor Xa (FXa) inhibition. FV-Short and protein S function as synergistic TFPIα-cofactors in inhibition of FX
Background: Optimisation of dopaminergic therapy may alleviate fluctuation-related pain in Parkinson’s disease (PD). Opicapone (OPC) is a third-generation, once-daily catechol-O-methyltransferase inhibitor shown to be generally well tolerated and efficacious in reducing OFF-time in two pivotal trials in patients with PD and end-of-dose motor fluctuations. The OpiCapone Effect on motor fluctuations
The historical turn in human rights studies is characterized by a deepcleavage between scholars who locate the origins of human rights inthe Atlantic Revolutions of the late 18th century, and scholars whoinstead focus on the post-WWII period in general, and on the 1970sin particular as a breakthrough decade for international humanrights. Against the background of what has been described as thethreThe historical turn in human rights studies is characterized by a deep cleavage between scholars who locate the origins of human rights in the Atlantic Revolutions of the late 18th century, and scholars who instead focus on the post-WWII period in general, and on the 1970s in particular as a breakthrough decade for international human rights. Against the background of what has been described as th
Objective Real-life management of patients with hypertension and chronic kidney disease (CKD) among European Society of Hypertension Excellence Centres (ESH-ECs) is unclear : we aimed to investigate it. Methods A survey was conducted in 2023. The questionnaire contained 64 questions asking ESH-ECs representatives to estimate how patients with CKD are managed. Results Overall, 88 ESH-ECS representa
Meddelanden från HT-biblioteken | januari 2024 Meddelanden från HT-biblioteken | januari 2024 Publicerad den 15 januari 2024 Foto: Anja Hoppe. God fortsättning! Här kommer årets första nyhetsbrev från HT-biblioteken. Som vanligt tipsar vi om månadens e-resurs, öppna workshoppar för studenter och för forskare, samt våra senaste nyförvärv. For information in English, please contact us. Innehållsfö
https://www.htbibl.lu.se/article/meddelanden-fraan-ht-biblioteken-januari-2024/ - 2026-06-22
