Filtyp
PURPOSE: There is a lack of validated imaging biomarkers for prediction of response to peptide receptor radionuclide therapy (PRRT). The primary objective was to evaluate if tumour burden at baseline PET/CT could predict treatment outcomes to PRRT with [ 177Lu]Lu-DOTA-TATE. Secondary objectives were to evaluate if there was a correlation between tumour burden and mean tumour absorbed dose (AD) dur
Objective A low expression of club cell secretory protein (CC16) and high levels of proinflammatory cytokines at preterm birth are associated with airway inflammation and more severe neonatal lung disease. The present study aimed to investigate if low levels of CC16, proinflammatory cytokines and vascular endothelial growth factors (VEGF) in tracheal aspirate early after birth were associated with
To examine whether the level of genetic risk in psychiatric disorders impacts the social functioning of affected individuals, we examine the relationship between genetic risk factors for major depression (MD), anxiety disorders (AD), bipolar disorder (BD), non-affective psychosis (NAP), alcohol use disorder (AUD), and drug use disorder (DUD) in disordered individuals and five adverse social outcom
A search is presented for flavour-changing neutral-current interactions involving the top quark, the Higgs boson and an up-type quark (q=u,c) with the ATLAS detector at the Large Hadron Collider. The analysis considers leptonic decays of the top quark along with Higgs boson decays into two W bosons, two Z bosons or a τ+τ- pair. It focuses on final states containing either two leptons (electrons or
Background: Many patients with psychotic disorders have persistent paranoid ideation and avoid social situations because of suspiciousness and anxiety. We investigated the effects of virtual-reality-based cognitive behavioural therapy (VR-CBT) on paranoid thoughts and social participation. Methods: In this randomised controlled trial at seven Dutch mental health centres, outpatients aged 18–65 yea
In the Swedish Instrument of Government from 1809, there was a balance of power between the King and the Parliament. From these two basic spheres of power (con-stituent powers), power was further divided into five parts (constituted powers). Through the introduction of parliamentarianism in the early 20th century, a redistri-bution of power took place in practice, but on paper the balance of power
Results from a wide range of searches targeting different experimental signatures with and without missing transverse momentum (ETmiss) are used to constrain a Two-Higgs-Doublet Model (2HDM) with an additional pseudo-scalar mediating the interaction between ordinary and dark matter (2HDM+a). The analyses use up to 139 fb−1 of proton–proton collision data at a centre-of-mass energy s=13 TeV recorde
Oxyanion holes play a major role in catalyzing enzymatic reactions, yet the corresponding energetics is frequently misunderstood. The main problem may be associated with the nontrivial nature of the electrostatic preorganization effect, without following the relevant formulation. That is, although the energetics of oxyanion holes have been fully quantified in early studies (which include both the
Purpose: Complications from diabetes mellitus can occur over time and although glycosylated hemoglobin (HbA1c) is a good biomarker for glycaemic control, other factors also contribute to the development of complications in type 1 diabetes. More markers able to identify the risk of complications are needed. This study aimed to investigate plasma levels of FGF21, Cystatin C, lipocalin-2, and MMP-9 i
Background: The water supply in the Gaza Strip, Palestine, has been unstable and under strain for decades, resulting in major issues with drinking water quality, reliability, and acceptability. In 2018, between 25% and 30% of Gazans did not have regular access to running water. The progressive deterioration of water infrastructure and concerns over the quality of piped water have resulted in a com
The purpose of the work that forms the basis of this thesis has been to investigate fundamental properties of amyloid β and tau self-assembly and their solubility. The results of this research are presented as five research articles. In Paper I, a solubility assay for determining the solubility of amyloid proteins is developed and its use demonstrated for the Aβ40 peptide. Paper II finds that tau
Background: Interferon-γ release assays (IGRAs) for tuberculosis infection (TBI) cannot distinguish different stages of the TBI spectrum (including spontaneously cleared infection). We investigated patterns of Mtb-specific blood mediators in people with and without TBI during tuberculosis preventive therapy (TPT). Methods: Individuals with likelihood of recent Mtb exposure, aged 15–25 years, with
The electroweak production of Z(νν¯) γ in association with two jets is studied in a regime with a photon of high transverse momentum above 150 GeV using proton–proton collisions at a centre-of-mass energy of 13 TeV at the Large Hadron Collider. The analysis uses a data sample with an integrated luminosity of 139 fb−1 collected by the ATLAS detector during the 2015–2018 LHC data-taking period. This
Average nucleotide identity analysis, based on whole genome sequences of 115 strains previously identified as Aerococcus urinae, an emerging uropathogen, discriminates at least six unique genomic taxa. The whole genome analysis affords clearer species boundaries over 16S rRNA gene sequencing and traditional phenotypic approaches for the identification and phylogenetic organization of Aerococcus sp
Background: Several studies have shown associations between cadmium (Cd) exposure and an increased risk of fractures. However, the size of the risk is still unclear and proper adjustment for smoking is a challenge. The aim of this study was to quantify the association between dietary cadmium measured in blood and fracture risk in the general Swedish population through a large population-based case
This thesis project aims to research the opportunities and challenges of development projects that integrate climate change adaptation (CCA) with youth empowerment in the rural community of Rangtse, Haa Dzongkhag in Bhutan. A vulnerability assessment was conducted by analyzing the exposure, sensitivity, and resilience of the Rangtse area to climate change through the dimensions of Gross National H
German forests are in a deteriorating state. The effects of climate change are increasingly showing and presenting society, and also forest owners, with the challenge of restructuring forests to become more climate resilient. At the same time there is a need to halt forest biodiversity loss and to further provide renewable resources that can be used to decarbonise its economy. At present forests’
Conference abstracts Knowledge for Sustainable Development – Lund University Research Conference 2 May 2022 | Sustainability Week in Lund 2022 Content Summary of research abstracts presented during the conference. 1. Theme I: Understanding and measuring processes in sustainable development 2. Theme II: Research for sustainability and change 3. Theme III: Implementation – obstacles, challenges, and
Øresundsnätverket februar 2021 S I D E 1 F E B R U A R 2 0 2 1 N Y H E D S B R E V N U M M E R 1 NÄTVERKET ØR E S UND SNÄ T V E R K E T F Ö R KØN SH I S T O R I S K F O R S KN I N G OM ØRESUNDNÄTVERKET Øresundsnätverket för kønshistorisk forskning samler forskere, formidlere, undervisere og andre med kønshistorisk interesse, med henblik på att udvikle og styrke kønshistorisk forskning og viden - p
https://www.cors.lu.se/sites/cors.lu.se/files/2021-03/%C3%98reundsna%CC%88tverket%20feb%202021_tillg.pdf - 2026-07-04
